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L-Pyroglutamic acid pentachlorophenyl ester

Supplier: Bachem Americas
Description: Sequence: Pyr-OPcp

Image Unavailable-TCM2803-25G

Boc-L-pyroglutamic acid methyl ester ≥98.0% (by GC)

Supplier: TCI America
Description: Methyl N-(tert-Butoxycarbonyl)-L-pyroglutamate, Purity: >98.0%(GC), CAS number: 108963-96-8, MF: C11H17NO5, Molecular Weight: 243.26, Synonym: (S)-1-Boc-5-oxopyrrolidine-2-carboxylic Acid Methyl Ester, Methyl N-Boc-L-pyroglutamate, Size: 5 G

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Methyl-DL-pyroglutamate ≥98.0% (by GC)

Supplier: TCI America
Description: Methyl DL-Pyroglutamate, Purity: >98.0%(GC), CAS number: 54571-66-3, Molecular Formula: C6H9NO3, MW: 143.14, Synonym: Methyl 5-Oxopyrrolidine-2-carboxylate, 5-Oxopyrrolidine-2-carboxylic Acid Methyl Ester, DL-Pyroglutamic Acid Methyl Ester, Size: 1G

Image Unavailable-TCE1135-1G

(S)-Ethyl-N-boc-pyroglutamate ≥97.0% (by HPLC, total nitrogen)

Supplier: TCI America
Description: Ethyl N-(tert-Butoxycarbonyl)-L-pyroglutamate, Purity: >97%(HPLC)N, CAS Number: 144978-12-1, MF: C12H19NO5, Synonym: N-(tert-Butoxycarbonyl)-L-pyroglutamic Acid Ethyl Ester, Ethyl (S)-1-(tert-Butoxycarbonyl)-5-oxopyrrolidine-2-carboxylate, Size: 5G

SDS

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(S)-Di-tert-butyl-5-oxopyrrolidine-1,2-dicarboxylate ≥98.0% (by HPLC, total nitrogen)

Supplier: TCI America
Description: Tert-Butyl N-(Tert-Butoxycarbonyl)-L-Pyroglutamate, Purity: >98.0%(HPLC)(N), Cas no: 91229-91-3, Molecular formula : C14H23NO5, Molecular weight : 285.34, Synonyms: Boc-Pyr-OtBu, tert-Butyl N-Boc-L-pyroglutamate, Size: 5G

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Benzyl (S)-1-Boc-5-oxopyrrolidine-2-carboxylate 98%

Supplier: Thermo Scientific Chemicals
Description: Benzyl (S)-1-Boc-5-oxopyrrolidine-2-carboxylate, 98%

SDS Certificates

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Z-Pyr-OH ≥98.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: N-Carbobenzoxy-L-pyroglutamic Acid, CAS Number: 32159-21-0, Purity: 98.0%, Molecular Formula: C13H13NO5, Molecular Weight: 263.25 g/mol, Synonyms: (S)-1-Cbz-5-oxopyrrolidine-2-carboxylic Acid, N-Cbz-L-pyroglutamic Acid, Z-Pyr-OH, Size: 25G

SDS

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N-(tert-Butoxycarbonyl)-L-pyroglutamic acid ≥98.0% (by HPLC, titration analysis)

Catalog Number: (TCB4083-5G)
Supplier: TCI America
Description: CAS Number: 53100-44-0
MDL Number: MFCD00672316
Molecular Formula: C10H15NO5
Molecular Weight: 229.23
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 119
Specific rotation [a]20/D: -34 deg (C=1, CHCl3)
Storage Temperature: 0-10°C

SDS


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N-(tert-Butoxycarbonyl)-L-pyroglutamic acid

Supplier: Bachem Americas
Description: Sequence: Boc-Pyr-OH

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(±)-2-Pyrrolidinone-5-carboxylic acid ≥99.0% (by titrimetric analysis)

Supplier: TCI America
Description: CAS Number: 149-87-1
MDL Number: MFCD00064322
Molecular Formula: C5H7NO3
Molecular Weight: 129.12
Purity/Analysis Method: >99.0% (T)
Form: Crystal
Melting point (°C): 184

SDS Certificates

Image Unavailable-TCP0573-100G

(S)-(-)-2-Pyrrolidinone-5-carboxylic acid ≥97.0% (by titrimetric analysis)

Catalog Number: (TCP0573-100G)
Supplier: TCI America
Description: CAS Number: 98-79-3
MDL Number: MFCD00005272
Molecular Formula: C5H7NO3
Molecular Weight: 129.12
Purity/Analysis Method: >97.0% (T)
Form: Crystal
Melting point (°C): 160
Specific rotation [a]20/D: -10 deg (C=5, H2O)

SDS Certificates


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Z-Pyr-OH

Supplier: Bachem Americas
Description: Sequence: Z-Pyr-OH

Product Image-10068-234

Anti-APP Rabbit Polyclonal Antibody

Catalog Number: (10068-234)
Supplier: Prosci
Description: Pyroglutamic acid truncated amyloid beta 11-40/42 may have a greater propensity to aggregate under physiological conditions. In addition, this pyrE modification has been implicated as the molecular species responsible for seeding larger oligomers of amyloid-beta. Pyroglutamic acid truncated amyloid beta 11-40/42’s exact involvement in the pathophysiology of Alzheimer’s disease has not been established
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(S)-(-)-2-Pyrrolidinone-5-carboxylic acid

Supplier: Bachem Americas
Description: Sequence: Pyr-OH

Product Image-10103-506

Anti-QPCT Rabbit Polyclonal Antibody

Catalog Number: (10103-506)
Supplier: Prosci
Description: QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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Human [Pyr11]-beta-Amyloid (11-42)

Supplier: Anaspec Inc
Description: This is a pyroglutamic acid modified beta-amyloid 11-42 peptide. Pyroglutamic acid modified isoforms form the major isoforms with up to 20% of the total beta-amyloid species.
Sequence: Pyr-VHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Molecular Weight: 3317.9 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

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