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Description: Zinc is an essential cofactor that is involved in cell growth and development, as well as in protein, nucleic acid and lipid metabolism. The transport of zinc across the cell membrane is crucial for correct enzyme and overall cell function. SLC39A11 (solute carrier family 39 (metal ion transporter), member 11), also known as ZIP11 (Zrt- and Irt-like protein 11), is a 342 amino acid multi-pass membrane protein belonging to the ZIP transporter family. Expressed as multiple alternatively spliced isoforms, SLC39A11 acts as a zinc-influx transporter and is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Catalog Number: 10493-722
Supplier: Bioss


Description: Zinc is an essential cofactor that is involved in cell growth and development, as well as in protein, nucleic acid and lipid metabolism. The transport of zinc across the cell membrane is crucial for correct enzyme and overall cell function. SLC39A11 (solute carrier family 39 (metal ion transporter), member 11), also known as ZIP11 (Zrt- and Irt-like protein 11), is a 342 amino acid multi-pass membrane protein belonging to the ZIP transporter family. Expressed as multiple alternatively spliced isoforms, SLC39A11 acts as a zinc-influx transporter and is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Catalog Number: 10493-718
Supplier: Bioss


Description: Transcriptional Repressor CTCF (CTCF) belongs to the CTCF Zinc-Finger Protein family. CTCF contains twelve C2H2-type zinc fingers and interacts with CHD8. CTCF is widely expressed in many tissues, and it is absent in primary spermatocytes. CTCF is involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. CTCF plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. In addition, CTCF is also indispensable in the epigenetic regulation and chromatin remodeling.
Catalog Number: 75790-748
Supplier: Prosci


Description: The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. TSHZ3 (teashirt zinc finger homeobox 3), also known as KIAA1474, TSH3 or ZNF537, is a 1,081 amino acid protein that contains one homeobox DNA-binding domain and five C2H2-type zinc fingers. Localized to the nucleus, TSHZ3 functions as a transcriptional regulator that is involved in developmental processes throughout the body. The gene encoding TSHZ3 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.
Catalog Number: 10662-718
Supplier: Bioss


Description: ZFP91 is a member of the zinc finger family of proteins. The gene product contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. In addition to the monocistronic transcript originating from this locus, a co-transcribed variant composed of ZFP91 and CNTF sequence has been identified. The monocistronic and co-transcribed variants encode distinct isoforms. The co-transcription of ZFP91 and CNTF has also been observed in mouse.
Catalog Number: 10106-338
Supplier: Prosci


Description: The ZNF654 gene, located on chromosome 17, encodes a protein that is part of the zinc finger family.
Catalog Number: 10105-502
Supplier: Prosci


Description: KLF3 is a zinc finger transcription factor that is known to function as a potent transcriptional repressor
Catalog Number: 10105-086
Supplier: Prosci


Description: This gene, located on chromosome 17, encodes a protein that is part of the zinc finger family.
Catalog Number: 10105-422
Supplier: Prosci


Description: This gene, ZNF670, which is located on chromosome 1, is predicted to encode a zinc finger protein, currently with unknown fucntion.
Catalog Number: 10106-332
Supplier: Prosci


Description: ZNF545 belongs to the krueppel C2H2-type zinc-finger protein family and may be involved in transcriptional regulation.
Catalog Number: 10104-928
Supplier: Prosci


Description: RNF169 contains 1 RING type zinc finger. The exact functions of RNF169 remain unknown.
Catalog Number: 10670-188
Supplier: Bioss


Description: ZNF521 Antibody: The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
Catalog Number: 10751-636
Supplier: Prosci


Description: ZNF581 contains 4 C2H2-type zinc fingers. ZNF581 may be involved in transcriptional regulation.
Catalog Number: 10111-754
Supplier: Prosci


Description: ZBTB10 contains 1 BTB (POZ) domain and 2 C2H2-type zinc fingers. ZBTB10 may be involved in transcriptional regulation.
Catalog Number: 10111-708
Supplier: Prosci


Description: Purity: Purified by antigen-affinity chromatography. Species Reactivity: Human Tested Applications: IHC-P, WB Pkg Size: 100 ul
Catalog Number: 89335-894
Supplier: Genetex


Description: ZBTB26 contains 4 C2H2-type zinc fingers. It may be involved in transcriptional regulation.
Catalog Number: 10106-272
Supplier: Prosci


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