You Searched For: 3,6-Dioxa-1,8-octanedithiol


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Supplier: Thermo Scientific Chemicals
Description: Amphotericin B, antifungal activity has been used against leishmaniasis caused by protozoan parasites of the Leishmania genus.
Catalog Number: (CA80055-790)
Supplier: MilliporeSigma
Description: A polyene antifungal antibiotic that nonspecifically induces loss of low molecular weight substances from cells

Catalog Number: (CA82026-728)
Supplier: Cytiva
Description: An antifungal, anti-yeast and anti-mold reagent.


Catalog Number: (BDH83628.400)
Supplier: VWR International
Description: 1,4-Dioxane ≥99.9%, HiPerSolv CHROMANORM® for HPLC, VWR Chemicals BDH®

Supplier: Peprotech
Description: Thrombomodulin (TM, CD141, THBD) is an endothelial cell-expressed, transmembrane glycoprotein that can form a complex with the coagulation factor, thrombin. The thrombomodulin/thrombin complex converts protein C to its activated form, protein Ca, which in turn proteolytically cleaves and deactivates factor Va and factor VIIIa, two essential components of the coagulation mechanism. This inactivation reduces the generation of additional thrombin, and thereby effectively prevents continued coagulation. Reduced levels of thrombomodulin can correlate with the pathogenesis of certain cardiovascular diseases, such as atherosclerosis and thrombosis. However, the serum levels of the truncated circulating form of thrombomodulin are typically elevated during inflammation and in the presence of various inflammatory-related diseases. The thrombomodulin protein contains 575 amino acids, including an 18 a.a. signal sequence, a 497 a.a. extracellular domain, a 24 a.a. transmembrane sequence, and a 36 a.a. cytoplasmic region. Recombinant Human Thrombomodulin is a 51.4 kDa, 491-amino-acid length glycoprotein containing the extracellular domain of thrombomodulin.
Supplier: Peprotech
Description: Thrombomodulin (TM, CD141, THBD) is an endothelial cell-expressed, transmembrane glycoprotein that can form a complex with the coagulation factor, thrombin. The thrombomodulin/thrombin complex converts protein C to its activated form, protein Ca, which in turn proteolytically cleaves and deactivates factor Va and factor VIIIa, two essential components of the coagulation mechanism. This inactivation reduces the generation of additional thrombin, and thereby effectively prevents continued coagulation. Reduced levels of thrombomodulin can correlate with the pathogenesis of certain cardiovascular diseases, such as atherosclerosis and thrombosis. However, the serum levels of the truncated circulating form of thrombomodulin are typically elevated during inflammation and in the presence of various inflammatory-related diseases. The thrombomodulin protein contains 575 amino acids, including an 18 a.a. signal sequence, a 497 a.a. extracellular domain, a 24 a.a. transmembrane sequence, and a 36 a.a. cytoplasmic region. Recombinant Human Thrombomodulin is a 51.4 kDa, 491-amino-acid length glycoprotein containing the extracellular domain of thrombomodulin.
Supplier: IBI Scientific
Description: Ultra Sieve Agarose is designed for high resolution electrophoresis where resolution of polyacrylamide gels are needed. Ultra Sieve Agarose improves clarity of gels and enhances visualization, even at high concentrations. Ultra Sieve Agarose has low viscosity, therefore high concentration gels can be made with high resolving capacity. The high gel strength, low concentration of 1.0-1.5% can also be made. Using TAE buffer, make a 1.8% gel for 400-1200bp, 3.0% gel for 150-800bp, and 4.5% gel for 15-400bp. To achieve the best resolution, store ultra sieve gels at +4-8°C for 30 minutes prior to use.

Catalog Number: (75789-850)
Supplier: Prosci
Description: Mouse Interleukin-36 alpha(Il-36a)is a member of the IL-1 family.IL¬1 alpha,IL¬1 beta and IL-18 are potent inflammatory cytokines whose activities are dependent on heterodimeric receptors of the IL-1R superfamily, and which are regulated by soluble antagonists. Il36a is expressed in many cells, including monocytes, B cells, and T cells, immune system and fetal brains. Il36a is a cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. It is a part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. It seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T cells to drive tissue infiltration, cell maturation and cell proliferation. It Induces the production of proinflammatory cytokines, including IL-12, Il-1 beta, IL-6, TNF-alpha and IL-23 in bone marrow-derived dendritic cells (BMDCs). Moreover, it is involved in dendritic cell maturation by stimulating the surface expression of CD80, CD86 and MHC class II and can induce the production of IFN-gamma, IL-4 and IL-17 by cultured CD4+ T cells and splenocytes. Il36a may play a role in proinflammatory effects in the lung: induces the expression of CXCL1 and CXCL2 in the lung, and the expression of TNF-alpha, IL-36c, IL-1A, IL-1B, CXCL1 and CXCL2 in isolated splenic CD11c+ alveolar macrophages. It may be involved in T cell maturation by stimulating the surface expression of CD40 and modestly CD80 and CD86 in splenic CD11c+ cells and CD4+ T cell proliferation.


Supplier: TCI America
Description: CAS Number: 32449-92-6
MDL Number: MFCD00135622
Molecular Formula: C6H8O6
Molecular Weight: 176.12
Purity/Analysis Method: >99.0% (T)
Form: Crystal
Melting point (°C): 178
Specific rotation [a]20/D: 18.5 deg (C=5, H2O)

SDS

Catalog Number: (CA45000-808)
Supplier: Corning
Description: This antimycotic interferes with fungal membrane permeability by forming channels in cell membranes, causing small molecules to leak from the cell. It is recommended for use in cell culture applications at 10 ml/L and is stable at 37 ºC for 3 days.

Supplier: Ace Glass
Description: Heavy-wall, borosilicate glass tubes are designed for polymerization and analysis of halogens by thermal decomposition in the presence of lime

Small Business Enterprise Product available on GSA Advantage®

Supplier: MP Biomedicals
Description: Dextran sulfate is a polyanionic derivative of dextran produced by esterification of Dextran with chlorosulphonic acid. Dextran sulfate sodium (DSS) is the sodium salt which is a white to off-white powder freely soluble in water and salt solutions to form a stable, clear solution. The sulfur content is approximately 17% which corresponds to an average of 1.9 sulfate groups per glucosyl residue of the dextran molecule.
Supplier: TCI America
Description: CAS Number: 6571-51-3
Molecular Formula: C15H22O2
Molecular Weight: 234.34
Purity/Analysis Method: >97.0% (GC)
Form: Crystal
Melting point (°C): 55

SDS

Supplier: TCI America
Description: (S)-(+)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)dimethylamine, Purity: >98%, CAS: 185449-80-3, MF: C22H18NO2P, MW: 359.36, Form: Crystal- Powder, White - Very pale yellow, Size: 5G

Supplier: TCI America
Description: (R)-(-)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)dimethylamine, Purity: >98%, CAS: 157488-65-8, MF: C22H18NO2P, MW: 359.36, Form: Crystal- Powder, White - Very pale yellow, Size: 1G
Supplier: TCI America
Description: (S,S,S)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)bis(1-phenylethyl)amine, Purity: >98.0%(HPLC), CAS: 209482-27-9, MF: C36H30NO2P, MW: 539.61, Form: Crystal- Powder, Size: 1G

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