Amphotericin B
Supplier: Thermo Scientific Chemicals
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Warning
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Synonyms:
(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
Amphotericin B, antifungal activity has been used against leishmaniasis caused by protozoan parasites of the Leishmania genus.
- Moisture and light sensitive
Amphotericin B trihydrate was observed to cause suppression of bone marrow progenitor cells and to induce Actinomycin D(CR001) sensitivity in drug resistant HELA cells in vitro.
Yellow powder
Soluble in aqueous buffers at pH 2.0 or 11.0. Insoluble at pH 6.0-7.0. Also soluble in DMSO or DMF
Formula:
C₄₇H₇₃NO₁₇ MW: 924.08 g/mol Storage Temperature: Refrigerator |
MDL Number:
MFCD00877763 CAS Number: 1397-89-3 EINECS: 215-742-2 Merck Index: 14,585 |
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