You Searched For: (\u00B1)-Aspartic+acid


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Catalog Number: (75794-376)
Supplier: Prosci
Description: Interleukin-18 (IL-18) is a costimulatory factor for production of interferon-gamma (IFN-gamma) in response to toxic shock and shares functional similarities with IL-12. IL-18 is synthesized as a precursor 24kDa molecule without a signal peptide and must be cleaved to produce an active molecule. IL-1 converting enzyme (ICE; Caspase-1) cleaves pro-IL-18 at aspartic acid in the P1 position, producing the mature, bioactive peptide that is readily released from the cells. It is reported that IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IFN-gamma is produced by activated T or NK cells and plays critical roles in the defense against microbiral pathogens. IFN-gamma activates macrophages and enhances NK activity and B cell maturation, proliferation and Ig secretion. IFN-gamma also induces expression of MHC class I and II antigens and inhibits osteoclast activation. IL-18 acts on T helper type-1 (Th1) T cells and in combination with IL-12 strongly induces them to produce IFN-gamma. Pleiotropic effects of IL-18 have also been reported, such as enhancement production of IFN-gamma and GM-CSF in peripheral blood mononuclear cells, production of Th1 cytokines, IL-2, GM-CSF, IFN-gamma in T cells and enhancement of Fas ligand expression by Th1 cells.


Supplier: Thermo Scientific Chemicals
Description: L(+)-Asparagine monohydrate 98+%
Catalog Number: (76576-160)
Supplier: AFG Bioscience
Description: Bovine Aspartate Aminotransferase (AST) ELISA Kit, AFG Bioscience


Catalog Number: (ABCA_AB9439-500UL)
Supplier: Abcam
Description: Rabbit polyclonal to L-Aspartate.

New Product


Catalog Number: (75794-374)
Supplier: Prosci
Description: Interleukin-18 (IL-18) is a costimulatory factor for production of interferon-gamma (IFN-gamma) in response to toxic shock and shares functional similarities with IL-12. IL-18 is synthesized as a precursor 24kDa molecule without a signal peptide and must be cleaved to produce an active molecule. IL-1 converting enzyme (ICE; Caspase-1) cleaves pro-IL-18 at aspartic acid in the P1 position, producing the mature, bioactive peptide that is readily released from the cells. It is reported that IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IFN-gamma is produced by activated T or NK cells and plays critical roles in the defense against microbiral pathogens. IFN-gamma activates macrophages and enhances NK activity and B cell maturation, proliferation and Ig secretion. IFN-gamma also induces expression of MHC class I and II antigens and inhibits osteoclast activation. IL-18 acts on T helper type-1 (Th1) T cells and in combination with IL-12 strongly induces them to produce IFN-gamma. Pleiotropic effects of IL-18 have also been reported, such as enhancement production of IFN-gamma and GM-CSF in peripheral blood mononuclear cells, production of Th1 cytokines, IL-2, GM-CSF, IFN-gamma in T cells and enhancement of Fas ligand expression by Th1 cells.


Catalog Number: (76705-414)
Supplier: AFG Bioscience
Description: Rat Aspartate Aminotransferase (AST) ELISA Kit


Catalog Number: (89415-778)
Supplier: Prosci
Description: Caspase-3 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-3 is synthesized as an inactive proenzyme that undergoes proteolytic cleavage by caspases 8, 9 and 10 to produce 2 subunits, termed p20 and p11. These subunits dimerize to form the active enzyme. Caspase-3 proteolytically cleaves and activates other proteins such as caspases 6, 7 and 9.


Catalog Number: (ABCA_AB189863-100U)
Supplier: Abcam
Description: Rabbit polyclonal to Aspartate Aminotransferase - C-terminal.

New Product


Catalog Number: (76710-918)
Supplier: AFG Bioscience
Description: Human Aspartate Aminotransferase(GOT/GPT) ELISA Kit


Catalog Number: (76707-328)
Supplier: AFG Bioscience
Description: Mouse Aspartate Aminotransferase, Cytoplasmic(GOT1) ELISA Kit


Supplier: Abcam
Description: Rabbit monoclonal [EPR10351] to Aspartate beta hydroxylase.

New Product

Catalog Number: (76744-272)
Supplier: ANTIBODIES.COM LLC
Description: Porcine aspartate aminotransferase, cytoplasmic ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of porcine aspartate aminotransferase, cytoplasmic in serum, plasma, tissue homogenates, and other biological fluids.


Supplier: Thermo Scientific Chemicals
Description: White to off-white
Catalog Number: (76715-662)
Supplier: AFG Bioscience
Description: Human D-Aspartate Oxidase(DDO) ELISA Kit


Supplier: Abcam
Description: Rabbit monoclonal [EPR22206-177] to Aspartate Aminotransferase - BSA and Azide free (Detector).

New Product

Catalog Number: (10084-092)
Supplier: Proteintech
Description: Caspase-6 belongs to caspase family of cysteinyl-aspartate specific proteases.Precursor of CASP6 produces two subunits, large (18kDa) and small (16kDa) that dimerize. It cleaves poly(ADP-ribose) polymerase, as well as lamins and is involved in the activation cascade of caspases responsible for apoptosis execution. Researches showed that CASP6 could be an early instigator of neuronal dysfunction and regulates B cell activation and differentiation into plasma cells by modifying cell cycle entry. IRAK3 is an important target for CASP6. It can reveal five bands of 28, 32, 36, 49, and 64 kDa in human neurons and fetal brain in western blot, the 32 and 28 kDa bands represent procaspase-6 and pro-arm caspase-6. Procaspase-6 is more abundant than pro-arm caspase-6 in adult tissue, whereas pro-arm caspase-6 is more abundant than pro-caspase-6 in fetal brain and cultured neurons. The higher molecular mass bands at 49 and 64 kDa likely represent dimers of p28 and p32.. In rat testis, it can be detected two bands of 34 kDa and 12 kDa or 14 kDa.


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