You Searched For: Z-Gly-Gly-Phe-Chloromethylketone


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Catalog Number: (10069-082)
Supplier: Prosci
Description: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.


Supplier: Bachem Americas
Description: Hepcidin-25 (hepatic bactericidal protein), also referred to as LEAP-1 (liver-expressed antimicrobial peptide) has been independently discovered by two groups in human blood ultrafiltrate and urine. The peptide which is predominantly expressed in the liver, belongs to a new vertebrate family of small antimicrobial peptides that contain 8 cysteine residues and show significant antibacterial and antifungal activity. Further investigations revealed that hepicidin is the principal iron-regulatory hormone in humans. It acts by binding to the iron exporter ferroportin, inducing its internalization and degradation, thereby blocking cellular iron efflux. Nemeth et al. demonstrated that the N-terminal part of the peptide hormone is essential for its activity.
Synonym: Hepc25 (human), LEAP-1 (human), Liver-Expressed Antimicrobial Peptide (human), PLTR (human), Putative Liver Tumor Regressor (human)
Sequence: H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH
Salt: Trifluoroacetate
Bonds: (Disulfide bonds between Cys7 and Cys23/Cys10 and Cys13/Cys11 and Cys19/Cys14 and Cys22)

Supplier: Bachem Americas
Description: See also H-1765, H-6560, and N-1000.

Catalog Number: (N-1220.0025BA)
Supplier: Bachem Americas
Description: See also Leupeptin (N-1000) and MG-132 (Calpain Inhibitor IV, N-1635).


Supplier: Bachem Americas
Description: Sequence: Z-Phe-chloromethylketone

Catalog Number: (N-1565.0005BA)
Supplier: Bachem Americas
Description: Peptide and amino acid chloromethyl ketones (CMK's) are irreversible inhibitors of cysteine proteases, but they also react with serine proteases. For our amino acid CMK's (e.g. TPCK, TLCK) see the corresponding product family in the 'Amino acid' section.


Supplier: Bachem Americas
Description: Peptide and amino acid chloromethyl ketones (CMK's) are irreversible inhibitors of cysteine proteases, but they also react with serine proteases. For our amino acid CMK's (e.g. TPCK, TLCK) see the corresponding product family in the 'Amino acid' section.

Supplier: Bachem Americas
Description: Sequence: Tos-Phe-chloromethylketone

Supplier: TCI America
Description: Product Categories: Bioscience, Oligopeptides
Other Product Names / Synonyms: H-Gly-Phe-OH

SDS

Catalog Number: (C-1745.0001BA)
Supplier: Bachem Americas
Description: Sequence: Z-Gly-Gly-Gly-Gly-OH


Supplier: Bachem Americas
Description: Sequence: Z-Gly-Gly-Gly-Gly-Gly-OH

Supplier: Bachem Americas
Description: Sequence: Z-Gly-Gly-OSu

Catalog Number: (470105-006)
Supplier: Ward's Science
Description: Tris-Gly-SDS Buffer Solution, Premixed Powder, Makes 6 L


Supplier: Bachem Americas
Description: Sequence: Z-Gly-Pro-Gly-Gly-Pro-Ala-OH

Supplier: Bachem Americas
Description: Sequence: Z-Gly-OSu

Supplier: Bachem Americas
Description: Sequence: Fmoc-Gly-OSu

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