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Catalog Number: (10665-618)
Supplier: Bioss
Description: Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP2, also known as NECAB2 (N-terminal EF-hand calcium binding protein 2), neuronal calcium-binding protein 2 or synaptotagmin-interacting protein 2 (Stip-2), is a 386 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and two EF-hand domains. Expressed in brain, EF-CBP2 is suggested to bind metabotropic glutamate receptor 5 (mGluR-5) in a calcium-regulated manner. The gene encoding EF-CBP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.


Catalog Number: (10089-170)
Supplier: Proteintech
Description: GLS, also named as GLS1 and KIAA0838, belongs to the glutaminase family. It catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Glutaminase-, glutamate-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease.The glutaminase band in AA/C1 cells is more intense than in HT29 cells, in accordance with measurements of glutaminase activity, and had the same molecular mass of approx. 63 kDa. Ping Gao et al. (2009) determined that mitochondrial glutaminase expression (GLS, molecular mass of ~58 kDa) is increased ~10-fold in response to Myc. It also reveals a molecular weight of 83-84 kDa as a phosphate-dependent glutaminase. GLS has 3 isoforms produced by alternative splicing and this antibody is specific to the 3 isoforms(KGA,GAM,GAC) of GLS.


Supplier: VWR
Description: Sodium dihydrogen phosphate, anhydrous ≥98.0%, Reagent Grade
Catalog Number: (10665-630)
Supplier: Bioss
Description: Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP2, also known as NECAB2 (N-terminal EF-hand calcium binding protein 2), neuronal calcium-binding protein 2 or synaptotagmin-interacting protein 2 (Stip-2), is a 386 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and two EF-hand domains. Expressed in brain, EF-CBP2 is suggested to bind metabotropic glutamate receptor 5 (mGluR-5) in a calcium-regulated manner. The gene encoding EF-CBP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.


Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Sodium Cyanide, Granular, BAKER ANALYZED® A.C.S. Reagent
Catalog Number: (CA71008-746)
Supplier: VWR
Description: Sodium nitrate ≥99.0%, crystals ACS

Catalog Number: (CAJTV025-05)
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Sodium Hexametaphosphate (Shmp) Gmp 1KG

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Sodium thiosulfate 0.1 N (N/10) in aqueous solution, StandARd® volumetric solution, Macron Fine Chemicals™
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Sodium hydroxide ≥98% (by acidimetry), pellets, BAKER ANALYZED® ACS, J.T.Baker®
Catalog Number: (JT3616-09)
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Sodium carbonate, anhydrous, Multi-Compendial


Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: GMP manufactured.
Catalog Number: (CA71008-568)
Supplier: VWR
Description: Sodium chloride ≥99.0%, crystals ACS

Catalog Number: (71008-686)
Supplier: VWR
Description: Sodium hydroxide 1 N in aqueous solution volumetric solution, traceable to NIST Standard Reference Material (SRM)

Catalog Number: (CA71008-478)
Supplier: VWR
Description: Sodium acetate, anhydrous ≥99.0% ACS

Catalog Number: (89416-252)
Supplier: Prosci
Description: NPAS3 Antibody: Neuronal PAS domain protein 3 (NPAS3) is a brain-enriched basic helix-loop-helix PAS domain transcription factor and is broadly expressed in the developing neuroepithelium and has recently found to be disrupted by genetic translocation in a family affected with schizophrenia. It was recently shown to be involved in the regulation of FGF signaling in the dentate gyrus by controlling the expression of the FGF receptor subtype 1 and in turn neurogenesis emanating from this region. NPAS3-null mice were growth-retarded and displayed brain defects that included reduced size of the anterior hippocampus, hypoplasia of the corpus callosum, and enlargement of the ventricles, as well as several behavioral abnormalities. Furthermore, these NPAS3-null mice also exhibited disruptions in several neurosignaling pathways involving glutamate, dopamine, and serotonin. These results demonstrate the essential role played by NPAS3 during structural and functional brain development. At least three isoforms of NPAS3 are known to exist.


Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Sodium hydroxide 1.0 N in aqueous solution, Biotech Reagent, J.T.Baker®
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