Print…

You Searched For: Leica+Biosystems


1,659  results were found

Refine Results Sort by
SearchResultCount:"1659"

Sort Results

List View Easy View

Rate These Search Results

Image Unavailable-CA76633-822

Anti-Epithelial Antigen Mouse Monoclonal Antibody [clone: Ber-EP4]

Supplier: Diagnostic Biosystems
Description: Epithelial antigen is a cell surface glycoprotein and is broadly distributed in epithelial cells and displays a highly conserved expression in carcinomas. Epithelial antigen has been shown to play an important role as a tumor cell marker in lymph nodes from patients with esophageal carcinoma. Epithelial antigen can be used to distinguish between basal cell and basosquamous carcinomas and squamous cell carcinoma of the skin.

Image Unavailable-CA76634-384

Anti-Epithelial antigen Mouse Monoclonal Antibody [clone: Ber-EP4]

Catalog Number: (CA76634-384)
Supplier: Diagnostic Biosystems
Description: Epithelial antigen is a cell surface glycoprotein and is broadly distributed in epithelial cells and displays a highly conserved expression in carcinomas. Epithelial antigen has been shown to play an important role as a tumor cell marker in lymph nodes from patients with esophageal carcinoma. Epithelial antigen can be used to distinguish between basal cell and basosquamous carcinomas and squamous cell carcinoma of the skin.
Image Unavailable-CA76635-204

Anti-Uroplakin II (UPK2) Rabbit Antibody

Supplier: Diagnostic Biosystems
Description: Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific differentiation products of urothelial cells. Uroplakins are markers of terminally differentiated urothelium. Uroplakin II (UPII) is a newly described sensitive marker for urothelial carcinoma (UC). The expression profile of UPII in different types of UC and its utility in the diagnostic setting are needed.

Image Unavailable-CA76634-368

Anti-MYOD1 Mouse Monoclonal Antibody [clone: 5.2F]

Catalog Number: (CA76634-368)
Supplier: Diagnostic Biosystems
Description: This antibody is specific to a 45 kDa protein, which is identified as MyoD1. This antibody is specific to an epitope of amino acid 3-56 in the N-terminus of mouse MyoD1. This antibody does not react with myogenin, Myf5 or Myf6. MyoD1 stains the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue but is expressed strongly in the tumor cell nuclei of rhabdomyosarcomas.
Image Unavailable-CA76635-116

Anti-Caspase 8 Rabbit Polyclonal Antibody

Supplier: Diagnostic Biosystems
Description: This antibody reacts with a 55 kDa protein. Caspase 8 has an N-terminal domain with sequence homology to the death effector domain (DED) of FADD. Caspase 8 binds to DED of FADD. Caspase 8 is activated by association with Fas/FADD death-inducing signaling complex to release two active subunits, P18 and P10 into the cytosol, where they activate other caspases amplifying the apoptotic signal.

Image Unavailable-CA76634-848

Anti-HER2/neu (c-erbB-2) Rabbit Monoclonal Antibody [clone: SP3]

Catalog Number: (CA76634-848)
Supplier: Diagnostic Biosystems
Description: This antibody recognizes a c-erbB-2 protein, which is a receptor tyrosine kinase of the c-erbB family. It is closely related in structure to the epidermal growth factor receptor. c-erbB-2 oncoprotein is detectable in a subset of breast and other adenocarcinomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.
Image Unavailable-CA76634-424

Anti-Mast Cell Tryptase Mouse Monoclonal Antibody [clone: AA1]

Catalog Number: (CA76634-424)
Supplier: Diagnostic Biosystems
Description: This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Mast cells contain a number of preformed chemicals mediators such as histamine, chymase, carboxypeptidase, and proteolytic tryptase. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation.
Image Unavailable-CA76634-230

Anti-SALL4 Mouse Monoclonal Antibody [clone: 6E3]

Supplier: Diagnostic Biosystems
Description: Sal-like protein 4 (SALL4) is a zinc-finger transcription factor that serves as a master regulator of embryonic pluripotency and is involved in processes associated with stem cell activities. SALL4 expression in germ cells makes it a useful marker for germ cell tumors such as seminoma, embryonal carcinoma, yolk sac tumors and teratomas. SALL4 expression is also seen in the spermatogonia of normal testis.

Image Unavailable-CA76635-160

Anti-Claudin 1 Rabbit Polyclonal Antibody

Supplier: Diagnostic Biosystems
Description: Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact, made up of a network of strands to act as a molecular gasket for preventing the leakage of ions, water etc., between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different claudin composition.

Image Unavailable-CA76633-716

Anti-Calponin Mouse Monoclonal Antibody [clone: CALP]

Supplier: Diagnostic Biosystems
Description: This antibody reacts with a 34 kDa protein known as calponin. Calponin, a calmodulin, binds tropomyosin and F-actin and is thought to be involved in the regulation of smooth muscle contraction. Expression of calponin is restricted to smooth muscle cells. Two isoforms of calponin exist whose molecular weights are 34 kDa and 29 kDa. 29 kDa isoform is primarily restricted to the muscle of the urogenital tract.

Image Unavailable-CA76634-738

Anti-CD8 T cell Rabbit Monoclonal Antibody [clone: SP16]

Supplier: Diagnostic Biosystems
Description: This antibody recognizes the CD8. The CD8 molecule consists of two chains, α and β, which are expressed as a disulphide-linked α/β heterodimer or as an α/α homodimer on T cell subset, thymocytes and NK cells. The majority of CD8+ T cells express CD8 as α/β heterodimer. CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 α chain (but not β chain).

Image Unavailable-CA76635-104

Anti-Beta-Catenin Rabbit Polyclonal Antibody

Supplier: Diagnostic Biosystems
Description: The catenins are structurally related cytoplasmic proteins which have been classified as alpha (α), beta (β), and gamma (γ), these proteins can bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. β-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule.

Image Unavailable-CA76634-558

Anti-PTEN Mouse Monoclonal Antibody [clone: 6H2.1]

Catalog Number: (CA76634-558)
Supplier: Diagnostic Biosystems
Description: PTEN gene is a tumor suppressor gene that maps to chromosome 10q23. PTEN, a novel tumor suppressor, functions as a regulator of both cell cycle progression and apoptosis ). Potentially, mutation and deletion of PTEN gene may result in a new signal transduction pathway related to human malignant tumors. Studies have demonstrated a reduction of PTEN expression in advanced breast cancers.
Image Unavailable-CA76634-480

Anti-Calponin Mouse Monoclonal Antibody [clone: CALP]

Catalog Number: (CA76634-480)
Supplier: Diagnostic Biosystems
Description: This antibody reacts with a 34 kDa protein known as calponin. Calponin, a calmodulin, binds tropomyosin and F-actin and is thought to be involved in the regulation of smooth muscle contraction. Expression of calponin is restricted to smooth muscle cells. Two isoforms of calponin exist whose molecular weights are 34 KDa and 29 kDa. 29 kDa isoform is primarily restricted to the muscle of the urogenital tract.
Image Unavailable-CA76634-174

Anti-PTEN Mouse Monoclonal Antibody [clone: 6H2.1]

Supplier: Diagnostic Biosystems
Description: PTEN gene is a tumor suppressor gene that maps to chromosome 10q23. PTEN, a novel tumor suppressor, functions as a regulator of both cell cycle progression and apoptosis ). Potentially, mutation and deletion of PTEN gene may result in a new signal transduction pathway related to human malignant tumors. Studies have demonstrated a reduction of PTEN expression in advanced breast cancers.

Image Unavailable-CA76634-688

Anti-Uroplakin II and III cocktail Multiple Recombinant Antibody

Catalog Number: (CA76634-688)
Supplier: Diagnostic Biosystems
Description: Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific differentiation products of urothelial cells. In non-neoplastic mammalian urothelium, UPs are expressed in the luminal surface plasmalemma of superficial (umbrella) cells, Uroplakin II/III cocktail is specific for tumors of urothelial origin and, when used in combination with other markers, can aid in the diagnosis of primary and metastatic tumors.
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
You must log in to order restricted items. We request that you provide the required business documentation to purchase this product for the first time.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
  • Government issued document with your organization's Resale Tax ID Number
  • Any other Government ID that includes the business name and address


VWR will not lift restrictions for residential shipping addresses.

-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is currently unavailable but limited stock may be available in our extended warehouse network. Please call 1-800-932-5000 and a VWR Customer Service Representative will help you.
465 - 480 of 1,659
no targeter for Bottom