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Image Unavailable-89285-532

Anti-CD20 Mouse Monoclonal Antibody (Biotin) [clone: LT20]

Catalog Number: (89285-532)
Supplier: Genetex
Description: Monoclonal Antibody to CD20 (Human) Biotin
Product Image-10101-196

Anti-CATSPER2 Rabbit Polyclonal Antibody

Catalog Number: (10101-196)
Supplier: Prosci
Description: Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. This gene is part of a tandem repeat on chromosome 15q14; the second copy of this gene is thought to be a pseudogene. Additional splice variants have been described but their full-length nature has not been determined.
Image Unavailable-89284-240

Anti-SRC Mouse Monoclonal Antibody [clone: 5D10C4]

Catalog Number: (89284-240)
Supplier: Genetex
Description: Mouse Monoclonal antibody [5D10C4] to Src
Image Unavailable-10465-732

Anti-DUSP2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10465-732)
Supplier: Bioss
Description: DUSP2 is a dual-specific thr/tyr phosphatase that is a physiologically relevant MAP kinase phosphatase. The gene is located on 2q11.2-q11 and contains 4 exons that span approximately 2.3kb. Under specific stress conditions, p53 regulates transcription of PAC1 through a new p53-binding site, and that PAC1 is necessary and sufficient for p53-mediated apoptosis.
Product Image-75846-490

Temperature Controller with Process and Limit Control, Ace Glass

Supplier: Ace Glass
Description: Temperature controller combines a Process control and a Limit control in one box.

Image Unavailable-10430-472

Anti-RNF139 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10430-472)
Supplier: Bioss
Description: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
Image Unavailable-89359-890

Anti-5HT3 Rabbit Polyclonal Antibody

Catalog Number: (89359-890)
Supplier: Genetex
Description: Serotonin (5-hydroxytryptamine, 5HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems. The 5HT3 receptors are distinguished from other 5HT receptors by their structure and function. 5HT3 receptors span the membrane only four times and are ligand-gated, cation-selective ion channels that mediate neuronal excitation and exocytotic release of neurotransmitters within the peripheral and central nervous systems.
Image Unavailable-77440-768

Anti-EMR3 Rabbit Polyclonal Antibody

Catalog Number: (77440-768)
Supplier: Bioss
Description: This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. (provided by RefSeq, Jul 2008).
Image Unavailable-10390-578

Anti-COX1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10390-578)
Supplier: Bioss
Description: Cytochrome c oxidase subunit I (COI or MTCO1) is one of three mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV. Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation. Complex IV is composed of 13 polypeptides. Subunits I, II, and III (MTCO1, MTCO2, MTCO3) are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc, and VIII are nuclear encoded. Mammalian MTCO1 has 12 membrane-spanning alpha-helices (I to XII).
Image Unavailable-89361-300

Anti-IL1R1 Rabbit Polyclonal Antibody

Catalog Number: (89361-300)
Supplier: Genetex
Description: Interleukin 1 (IL-1), which has a role as a mediator in inflammation, actually consists of 2 separate but related proteins, IL-1 alpha and IL-1 beta. Cell surface receptors for the 2 forms of IL-1 are identical. IL-1R Type I contains a single membrane-spanning segment, a large cytoplasmic region, and an extracellular, IL-1 binding portion composed of 3 immunoglobulin-like domains.
Image Unavailable-89367-408

Anti-EFEMP1 Rabbit Polyclonal Antibody

Catalog Number: (89367-408)
Supplier: Genetex
Description: This gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Two transcripts with distinct 5' UTR have been described; the resulting proteins have distinct N-terminal amino acid sequences. Translation initiation from internal methionine residues was observed with in vitro translation. A signal peptide sequence is predicted for translation initiation sites 1, 2, and 4. The protein isoforms contain 5 or 6 calcium-binding EGF2 domains and 5 or 6 EGF2 domains. Mutations in this gene cause the retinal disease Malattia Leventinese.
Image Unavailable-10663-536

Anti-GIPC-2 Rabbit Polyclonal Antibody

Catalog Number: (10663-536)
Supplier: Bioss
Description: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Product Image-10103-564

Anti-JPH3 Rabbit Polyclonal Antibody

Catalog Number: (10103-564)
Supplier: Prosci
Description: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. JPH3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in the gene that encodes JPH3 protein. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Image Unavailable-102980-208

Toxoplasma gondii Recombinant Profilin (from Escherichia coli)

Supplier: Adipogen
Description: TLR11, an innate sensor for profilin (Toxoplasma gondii), is an intracellular receptor that resides in the endoplasmic reticulum. The 12 membrane-spanning endoplasmic reticulum-resident protein UNC93B1 interacts directly with TLR11 and regulates the activation of dendritic cells in response to profilin (Toxoplasma gondii) and parasitic infection in vivo. TLR12, a previously uncharacterized TLR, also recognizes profilin from Toxoplasma gondii. TLR12 is sufficient for recognition of profilin by plasmacytoid dendritic cells (pDCs), whereas TLR11 and TLR12 are both required in macrophages and conventional DCs. In contrast to TLR11, TLR12-deficient mice succumb rapidly to T. gondii infection.

Image Unavailable-76117-730

Anti-RNF139 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76117-730)
Supplier: Bioss
Description: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
Product Image-10748-666

Anti-ORAI2 Rabbit Polyclonal Antibody

Catalog Number: (10748-666)
Supplier: Prosci
Description: ORAI2 Antibody: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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