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Product Image-10460-456

Anti-INPPL1 Rabbit Polyclonal Antibody

Catalog Number: (10460-456)
Supplier: Bioss
Description: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
Image Unavailable-10460-472

Anti-INPPL1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10460-472)
Supplier: Bioss
Description: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
Image Unavailable-10460-478

Anti-INPPL1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10460-478)
Supplier: Bioss
Description: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
Image Unavailable-10460-470

Anti-INPPL1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10460-470)
Supplier: Bioss
Description: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
Image Unavailable-TCB3470-100MG

5-Bromo-3-indolyl-β-D-galactopyranoside ≥98.0% (by HPLC) for biochemical research

Supplier: TCI America
Description: [for Biochemical Research]
CAS Number: 97753-82-7
MDL Number: MFCD00063691
Molecular Formula: C14H16BrNO6
Molecular Weight: 374.19
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Specific rotation [a]20/D: -34.5 deg (C=1, DMF:H2O=1:1)
Storage Temperature: <0°C

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Product Image-RC8385-32

Tetraethylammonium bromide 40% (w/w) in glacial acetic acid

Catalog Number: (RC8385-32)
Supplier: Ricca Chemical
Description: Tetraethylammonium bromide 40% (w/w) in glacial acetic acid

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Image Unavailable-AAH58247-AD

Cyclobutylzinc bromide 0.5 M in THF

Catalog Number: (AAH58247-AD)
Supplier: Thermo Scientific Chemicals
Description: Cyclobutylzinc bromide, 0.5M in THF, Molecular Formula: C4H7BrZn, Color: yellow to brown to black, Form: liquid, packaged under Argon in resealable ChemSeal bottles, Size: 50ML

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Image Unavailable-CAAA11113-59

Aluminium bromide ≥98%

Supplier: Thermo Scientific Chemicals
Description: Alkylation, bromination and isomerization catalyst in organic synthesis

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Image Unavailable-CAAAAL04311-14

(1-Tetradecyl)triphenylphosphonium bromide 97%

Supplier: Thermo Scientific Chemicals
Description: (1-Tetradecyl)triphenylphosphonium bromide 97%

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Image Unavailable-76220-334

1-Methyl-3-pentylimidazolium bromide ≥98.0% (by HPLC)

Supplier: TCI America
Description: 1-Methyl-3-pentylimidazolium Bromide, Purity: >98.0%(HPLC), CAS number: 343851-31-0, Molecular Formula: C9H17BrN2, Molecular Weight: 233.15, Synonyms: 1-Methyl-3-pentyl-1H-imidazol-3-ium Bromide, Form: Clear, Colorless - Yellow red, Size: 5G

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Image Unavailable-AAH54134-AE

2,4-Dimethylphenylmagnesium bromide 0.5 M in 2-MeTHF (2-methyltetrahydrofuran)

Catalog Number: (AAH54134-AE)
Supplier: Thermo Scientific Chemicals
Description: 2, 4-Dimethylphenylmagnesium bromide, 0.5M in 2-MeThf, Cas no. 34589-46-3, Molecular formula: C8H9BrMg, Form: Liquid, Color: Yellow to gold to grey, size: 100ml

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Product Image-76620-092

Decyl-β-D-glucopyranoside ≥97%

Supplier: AFG Bioscience
Description: Decyl-β-D-glucopyranoside ≥97%

Image Unavailable-CAAAA15878-0B

(Methyl)triphenylphosphonium bromide 98+%

Supplier: Thermo Scientific Chemicals
Description: (Methyl)triphenylphosphonium bromide 98+%

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Product Image-76509-146

α-Hydroxy-o-tolyl-β-D-glucopyranoside

Catalog Number: (76509-146)
Supplier: RPI
Description: D-(-)Salicin, Purity: >/=99.0%, Hplc, Appearance: White to off white powder, CAS Number: 138-52-3, Molecular Weight: 286.3, Chemical Formula: C13H18O7, Solubility: Water, Size: 500G
Image Unavailable-TCM2237-250G

Methylmagnesium bromide ∼30% ∼3 mol/L in MeTHF (2-methyltetrahydrofuran)

Catalog Number: (TCM2237-250G)
Supplier: TCI America
Description: Methylmagnesium Bromide, CAS Number: 75-16-1, Molecular Formula: CH3BrMg, Molecular Weight: 119.24, (ca. 30% in 2-Methyltetrahydrofuran, ca. 3mol/L), Form: Liquid, Size: 250G

SDS


Image Unavailable-CAAAAB22510-22

Zinc bromide, anhydrous 98%

Supplier: Thermo Scientific Chemicals
Description: Zinc bromide, anhydrous 98%

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