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Product Image-CA97026-666

EDTA solution 1M

Catalog Number: (CA97026-666)
Supplier: Hach
Description: For determination of calcium and magnesium hardness in water by the Calmagite Colorimetric method
Image Unavailable-10781-078

Human Recombinant TIMP-1 (from E. coli)

Supplier: Peprotech
Description: TIMP-1 is an extracellular inhibitor of MMPs, including MMP-1, -2, -3, -7, -8, -9, -10, -11, -12, -13, and -16. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-1 can also act through an MMP-independent mechanism to promote erythropoiesis by stimulating proliferation and differentiation of erythroid progenitors. Recombinant Human TIMP-1 is a 20.6 kDa protein containing 184 amino acid residues.

Image Unavailable-CA700009-102

Bromothymol blue ACS

Supplier: Spectrum Chemicals
Description: Bromothymol Blue, Reagent, ACS is a pH indicator for weak acids and bases. It is mostly used in applications that require measuring substances that would have a relatively neutral pH (near 7), such as managing the pH of pools and fish tanks.

Product Image-10091-060

Anti-neuromedin B Rabbit Polyclonal Antibody

Catalog Number: (10091-060)
Supplier: Proteintech
Description: Neuromedin B (NMB) is a bombesin-like peptide, which inhibits food intake and modulates stress-related behaviour. It exerts its function via NMB receptor (NMB-R). NMB is encoded in a 76-amino acid precursor. The mature NMB was reported to be a 10-amino-acid peptide, giving two bands of 1.2 kDa and 1.5 kDa in western blotting. NMB is expressed in brain, gastrointestinal tract, pancreas, adrenals, and adipose tissue. It regulates exocrine and endocrine secretions, cell growth, body temperature and blood pressure and glucose level in vivo.
Product Image-10090-964

Anti-NDUFB2 Rabbit Polyclonal Antibody

Catalog Number: (10090-964)
Supplier: Proteintech
Description: The multisubunit NADH:ubiquinone oxidoreductase (complex I) is the first enzyme complex in the electron transport chain of mitochondria. NDUFB2, also named as CI-AGGG, is a nuclear encoded subunit located in the hydrophobic protein fraction of complex I. It may have a role in the regulation of molecular changes during the global cardiac ischemia/reperfusion injury during cardiopulmonary bypass (CPB). The full length 12 kDa protein has a transit peptide with 33 amino acids.
Image Unavailable-76085-368

Anti-SLC27A2/ACSVL1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76085-368)
Supplier: Bioss
Description: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).
Image Unavailable-103001-346

Human Recombinant MMP-12 (from E. coli)

Supplier: Anaspec Inc
Description: Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. MMP-12 (macrophage elastase) is involved in smoke-induced emphysema, tumor and other diseases. MMP-12 is secreted as a 54-kDa zymogen and becomes the mature 45-kDa active form after proteolytic cleavage. MMP-12 has a broad range of substrates, including α-1 proteinase inhibitor, α-2 antiplasmin, plasminogen activator inhibitor-2, collagen IV, laminin, fibronectin, elastin, but not interstitial collagens.

The sequence (Accession # NP_002417) corresponding to the catalytic domain (aa 106-267) of Human MMP-12 was expressed in E. coli. The recombinant human MMP-12 was purified from bacterial lysate and refolded using proprietary technique. The molecular weight of the recombinant Human MMP-12 Catalytic Domain is 18 kDa.

Image Unavailable-TCO0434-1G

3-Oxabicyclo[3.1.0]hexane-2,4-dione ≥98.0% (by GC, titration analysis)

Supplier: TCI America
Description: CAS Number: 5617-74-3
MDL Number: MFCD00126929
Molecular Formula: C5H4O3
Molecular Weight: 112.08
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Boiling point (°C): 114
Melting point (°C): 60

SDS Certificates

Image Unavailable-10406-120

Anti-ADAM12 Rabbit Polyclonal Antibody

Catalog Number: (10406-120)
Supplier: Bioss
Description: ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNF?(tumor necrosis factor ?, and modulation of the neurogenic function of Notch and Delta (1-3). ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (Integrin ligand), a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail (1-3). ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone, and muscle, and catalyze proteolysis, adhesion, fusion, and intracellular signaling (3). ADAM 12 (Meltrin-a) is produced as 2 differentially spliced isoforms, a 718 amino acid secreted form (ADAM12S) and a 881 amino acid membrane-bound form (ADAM12L), and is involved in egg-sperm fusion (4-6).
Image Unavailable-10477-522

Anti-CCDC38 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10477-522)
Supplier: Bioss
Description: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC38 (coiled-coil domain containing 38) is a 563 amino acid protein encoded by a gene that maps to human chromosome 12q23.1. Encoding over 1,100 genes, chromosome 12 comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Image Unavailable-76107-224

Anti-CCDC38 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76107-224)
Supplier: Bioss
Description: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC38 (coiled-coil domain containing 38) is a 563 amino acid protein encoded by a gene that maps to human chromosome 12q23.1. Encoding over 1,100 genes, chromosome 12 comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Image Unavailable-CA10817-762

Anti-NOTCH1 Mouse Monoclonal Antibody [clone: N253/32]

Catalog Number: (CA10817-762)
Supplier: Biolegend
Description: Notch 1, Monoclonal Antibody, Purified, Clone: N253/32, Host: Mouse, Species Reactivity: Mouse, Rat, Immunogen: Raised against a fusion protein to amino acids 20-216 of mouse Notch1, Isotype: IgG1, Synonym: N1, Mis6, lin-12, Application: WB, IHC, Size: 100 ul
Product Image-89415-620

Anti-CASP12 Rabbit Polyclonal Antibody

Catalog Number: (89415-620)
Supplier: Prosci
Description: Caspase-12 Antibody: (Small)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.
Product Image-89150-956

Protoporphyrin IX ≥95% (by HPLC)

Supplier: Enzo Life Sciences
Description: Protoporphyrin IX free acid, as distinct from its zinc salt (which inhibits heme oxygenase), activates soluble guanylyl cyclase (sGC) by binding directly to the enzyme. A useful reagent in cases where the use of nitric oxide (NO) or nitric oxide donors is undesirable.

Certificates

Image Unavailable-RL010-001-B54

Mouse recombinant Il27 (from E. coli)

Catalog Number: (RL010-001-B54)
Supplier: Rockland Immunochemical
Description: Mouse IL-27/p28 Subunit, also known as Interleukin-30, is a member of the IL-12 family of cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), the heterodimer formed is IL-27. Mouse p28 is a proinflammatory cytokine inducing immunomodulatory effects. Current research is underway to delineate specific biological functions. Recombinant mouse p28 is a single-chain 207 amino acid peptide with a mass of approximately 23,697 Daltons.

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L(+)-Tartaric acid ≥99.7%, granulated FCC

Supplier: Spectrum Chemical Mfg. Corp.
Description: Tartaric Acid, Granular, FCC is used as an leavening additive and flavoring agent. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications.

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