You Searched For: STEMCELL Technologies

Catalog Number: (MSPP-100-0456)

Supplier: STEMCELL Technologies

Description: Rat monoclonal IgG2b antibody against mouse TER119, biotin-conjugated.

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Catalog Number: (MSPP-07516)

Supplier: STEMCELL Technologies

Description: For probe-based assays and arrays.

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Catalog Number: (MSPP-100-0209)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal antibody against human, rhesus, cynomolgus CD81, unconjugated.

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Catalog Number: (MSPP-100-1611)

Supplier: STEMCELL Technologies

Description: Hamster (Armenian) monoclonal antibody against mouse T cell receptor beta, APC-conjugated.

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Supplier: STEMCELL Technologies

Description: Animal component-free collagenase for the digestion of native collagen fibrils.

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Supplier: STEMCELL Technologies

Description: Interleukin 10 (IL-10) is the founding member of the IL-10 family of class II cytokines. All of the IL-10 cytokine family members have a four-helix bundle consisting of α-helical folds. Upon binding to its receptor, IL-10 activates signaling through JAK1 and STAT3. It is produced by dendritic cells, macrophages, and CD4+ T cells, as well as mast cells, NK cells, neutrophils, and B cells, under specific stimulating conditions (Saraiva and O'Garra). IL-10 can inhibit the expression of pro-inflammatory cytokines and promote healing processes, and is important for the function of regulatory T cells. IL-10 also enhances B cell proliferation, immunoglobulin secretion, and class II MHC expression, while IL-10 produced by macrophages inhibits activation of neighboring macrophages, thus allowing a level of self-regulation (Ouyang <i>et al.</i>).

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Catalog Number: (MSPP-17972)

Supplier: STEMCELL Technologies

Description: Immunomagnetic enrichment of untouched human ILC2 cells.

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Catalog Number: (MSPP-02008)

Supplier: STEMCELL Technologies

Description: For detection and measurement of human interleukin 4.

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Catalog Number: (MSPP-100-0243)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human, mouse CD105 (endoglin).

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Catalog Number: (MSPP-781941006)

Supplier: STEMCELL Technologies

Description: Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Yang <i>et al.</i>; Dorssers <i>et al.</i>; Broughton <i>et al.</i>). IL-3 is produced by activated T cells and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by basophils and eosinophils (Broughton <i>et al.</i>). The IL-3 receptor consists of a unique alpha subunit (CD123) and a beta common subunit (βc or CD131) that is shared with the receptors for IL-5 and GM-CSF, and is the principal signal transduction subunit for these cytokines. IL-3 binding to the heterodimeric receptor activates JAK/STAT, MAPK, and PI3K signaling pathways (Woodcock <i>et al.</i>).

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Catalog Number: (MSPP-781461006)

Supplier: STEMCELL Technologies

Description: Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Yang <i>et al.</i>; Dorssers <i>et al.</i>; Broughton <i>et al.</i>). IL-3 is produced by activated T cells and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by basophils and eosinophils (Broughton <i>et al.</i>). The IL-3 receptor consists of a unique alpha subunit (CD123) and a beta common subunit (βc or CD131) that is shared with the receptors for IL-5 and GM-CSF, and is the principal signal transduction subunit for these cytokines. IL-3 binding to the heterodimeric receptor activates JAK/STAT, MAPK, and PI3K signaling pathways (Woodcock <i>et al.</i>). This product is animal component-free.

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Catalog Number: (MSPP-100-1620)

Supplier: STEMCELL Technologies

Description: Rat monoclonal antibody against mouse IL-4, APC-conjugated.

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Catalog Number: (MSPP-100-0463)

Supplier: STEMCELL Technologies

Description: (C3H x BALB/c) F1 hybrid monoclonal IgG2a antibody against mouse NK1.1 (CD161).

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Catalog Number: (MSPP-780431006)

Supplier: STEMCELL Technologies

Description: Interleukin 33 (IL-33) is a pro-inflammatory cytokine from the IL-1 family. It binds to ST2 receptor and activates NF-κB and MAPK pathways. IL-33 is expressed by epithelial cells, smooth muscle cells, and fibroblasts in various tissues and organs, as well as resting basophils, mast cells, eosinophils, natural helper cells, group 2 innate lymphoid cells, dendritic cells, and activated macrophages (Schmitz <i>et al.</i>; Yasuda <i>et al.</i>). It contributes to allergic inflammation by stimulating production of the cytokines IL-4, IL-5, and IL-13, and stimulates host defense against microbial and viral infections (Liew; Yasuda <i>et al.</i>). In the central nervous system, IL-33 is produced by endothelial cells and astrocytes. It induces proliferation of microglia and mediates production of pro-inflammatory cytokines (Yasuoka <i>et al.</i>).

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Catalog Number: (MSPP-100-0513)

Supplier: STEMCELL Technologies

Description: For culture and expansion of human hematopoietic cells.

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Catalog Number: (MSPP-60007)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD2, unconjugated.

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