You Searched For: STEMCELL Technologies

Catalog Number: (MSPP-780301006)

Supplier: STEMCELL Technologies

Description: Interleukin 13 (IL-13) is a type I cytokine, and signals through type I cytokine receptors to activate JAK/STAT and IRS-1/IRS-2 pathways. IL-13 is produced by T cells and innate lymphoid cells (Pulendran and Artis) and it inhibits production of pro-inflammatory cytokines, prostaglandins, and reactive oxygen and nitrogen species by monocytes and macrophages (Hershey). Unlike human B cells, IL-13 has no effect on mouse B cell development and function. IL-13 promotes eosinophil survival, activation, and recruitment, and also activates mast cells (Hershey). IL-13 regulates gastrointestinal parasite expulsion, airway hyperresponsiveness, allergic inflammation, tissue eosinophilia, goblet cell hyperplasia, intracellular parasitism, tissue remodeling, tumor cell growth, and fibrosis. IL-13 induces hypercontractility of smooth muscles by directly acting on the muscle cells as well as the enteric nerves (Wynn).

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Catalog Number: (MSPP-100-1081)

Supplier: STEMCELL Technologies

Description: Goat polyclonal antibody against mouse IgG (H+L).

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Catalog Number: (MSPP-02010)

Supplier: STEMCELL Technologies

Description: For detection and measurement of human interleukin 5.

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Catalog Number: (MSPP-60039)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human, mouse CD105 (endoglin), unconjugated.

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Catalog Number: (MSPP-60066)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human, chimpanzee, gibbon TRA-2-49 (tissue non-specific alkaline phosphatase), unconjugated.

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Catalog Number: (MSPP-100-0020)

Supplier: STEMCELL Technologies

Description: Maturation kit for the generation of microglia from human ES and iPS cell-derived microglia precursors.

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Catalog Number: (MSPP-04900)

Supplier: STEMCELL Technologies

Description: Medium without cytokines.

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Catalog Number: (MSPP-100-1066)

Supplier: STEMCELL Technologies

Description: Rabbit polyclonal antibody against human villin 1.

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Catalog Number: (MSPP-100-1615)

Supplier: STEMCELL Technologies

Description: Hamster (Armenian) monoclonal antibody against mouse CD69, PE-Cy7-conjugated.

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Catalog Number: (MSPP-100-0437)

Supplier: STEMCELL Technologies

Description: Rat monoclonal IgG2b antibody against human, mouse, rhesus CD11b, FITC-conjugated.

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Catalog Number: (MSPP-100-0139)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal antibody against human, rhesus, cynomolgus CD63, unconjugated.

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Catalog Number: (MSPP-60069)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgM, kappa isotype control antibody, unconjugated.

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Catalog Number: (MSPP-07931)

Supplier: STEMCELL Technologies

Description: CryoStor® CS10 is a uniquely formulated, serum-free, animal component-free and defined cryopreservation medium containing 10% dimethyl sulfoxide (DMSO). Designed to preserve cells in low temperature environments (-80 °C to -196 °C).

Catalog Number: (MSPP-05270)

Supplier: STEMCELL Technologies

Description: Defined, animal component-free medium for differentiation of human ES and iPS cells to multiple lineages.

Catalog Number: (MSPP-100-1355)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal antibody against human, monkey CD137 (ILA).

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Catalog Number: (MSPP-780271997)

Supplier: STEMCELL Technologies

Description: Interleukin 12 (IL-12p70) is a heterodimeric cytokine composed of p35 and p40 subunits. IL-12 is produced by monocytes, macrophages, dendritic cells, neutrophils, and B cells in response to bacterial products and cytokines such as IFN-γ. The IL-12 receptor is expressed on T, NK, and dendritic cells. Upon binding, IL-12 initiates signaling via the JAK/STAT signaling pathway and stimulates NK, B, and T cells to produce IFN-γ (Watford <i>et al.</i>). It also regulates cytokine synthesis, proliferation of T and NK cells, and stimulates differentiation of CD4+ and CD8+ T cells (Germann and Rüde). Mice that are deficient in IL-12 are susceptible to many intracellular pathogens and have impaired IFN-γ secretion, Th1 differentiation, and NK cytolytic activity; however, Th2 development and IL-4 production are enhanced (Watford <i>et al.</i>).

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