You Searched For: STEMCELL Technologies

Catalog Number: (MSPP-60014)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human, chimpanzee, horse CD38, unconjugated.

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Catalog Number: (MSPP-100-0582)

Supplier: STEMCELL Technologies

Description: Chimeric mouse (V), human (C) monoclonal IgG antibody against SARS-CoV, SARS-CoV-2 (2019-nCoV) S protein (HEK293-expressed recombinant).

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Supplier: STEMCELL Technologies

Description: Interleukin 1 alpha (IL-1α) is a member of the IL-1 family and a dual-function cytokine. Both the unprocessed precursor and a processed IL-1α protein signal through IL-1 receptor type 1 (IL-1R1). Various cells, including keratinocytes, thymic epithelium, hepatocytes, endothelial cells, fibroblasts, and the epithelial cells of mucous membranes, have high levels of intracellular IL-1α precursor. The precursor is also expressed on the surface of monocytes and B lymphocytes (Netea <i>et al.</i>). IL-1α recruits infiltrating cells to a site of injury during necrosis and plays an important role during processes of sterile inflammation (Cohen <i>et al.</i>; Rider <i>et al.</i>). During hypoxia, IL-1α contributes to angiogenesis (Carmi <i>et al.</i>). Studies in mice show that IL-1α is produced by microglia-like cells after ischemic brain injury, which contributes to the inflammation (Luheshi <i>et al.</i>).

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Catalog Number: (MSPP-100-1456)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal antibody against human perforin, PE-conjugated.

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Catalog Number: (MSPP-100-1624)

Supplier: STEMCELL Technologies

Description: Hamster (Armenian) monoclonal antibody against mouse CD80 (B7-1), APC-conjugated.

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Catalog Number: (MSPP-780343)

Supplier: STEMCELL Technologies

Description: Interleukin 1 beta (IL-1β) is synthesized as an inactive precursor protein or pro-IL-1β. This precursor is cleaved intracellularly by caspase 1 (IL-1β convertase) to form the active form of the protein that is later secreted (Allan <i>et al.</i>). IL-1β binds to IL-1 receptor and activates intracellular signaling via the MAPK or NF-κB pathway. IL-1β is released by monocytes, tissue macrophages, and dendritic cells in response to infection or injury and induces expression of acute-phase proteins. It also promotes the infiltration of inflammatory and immunocompetent cells from the circulation into the extravascular space and affected tissues, by stimulating the expression of adhesion molecules on endothelial cells. IL-1β also affects other immune cells; for example, it co-stimulates T cell functions together with an antigen or mitogen. It also stimulates Th17 differentiation and B cell proliferation in an IL-6-dependent manner.

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Catalog Number: (MSPP-02024)

Supplier: STEMCELL Technologies

Description: For detection and measurement of mouse interleukin 5.

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Catalog Number: (MSPP-02004)

Supplier: STEMCELL Technologies

Description: For detection and measurement of human interleukin 1 beta.

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Catalog Number: (MSPP-02006)

Supplier: STEMCELL Technologies

Description: For detection and measurement of human interleukin 2.

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Catalog Number: (MSPP-100-1348)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal antibody against human CD69 (AIM).

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Catalog Number: (MSPP-782071006)

Supplier: STEMCELL Technologies

Description: Interleukin 19 (IL-19) is a member of the IL-10 cytokine family and is produced by keratinocytes, B cells, and monocytes (Romer <i>et al.</i>; Wolk <i>et al.</i>). Expression of IL-19 can be induced by granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide (LPS; Gallagher <i>et al.</i>). IL-19 is considered to be a proinflammatory cytokine, as it upregulates IL-6 and tumor necrosis factor alpha (TNF-α; Liao <i>et al.</i> 2002). IL-19 binds the IL-20 receptor complex (IL-20R) which comprises IL-20R alpha and IL-20R beta to activate the STAT3 pathway (Dumoutier <i>et al.</i>). IL-19 also induces T-helper cell differentiation towards a Th2 response, resulting in the production of IL-10 and additional IL-19 (Liao <i>et al.</i> 2002; Liao <i>et al.</i> 2004). IL-19 has been implicated in aging, vascular disease, Type I diabetes, and rheumatoid arthritis.

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Catalog Number: (MSPP-100-0872)

Supplier: STEMCELL Technologies

Description: Differentiation and maturation kits for generation of motor neurons from human pluripotent stem cells.

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Catalog Number: (MSPP-60072)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG2b, kappa isotype control antibody, unconjugated.

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Catalog Number: (MSPP-60074)

Supplier: STEMCELL Technologies

Description: Rat monoclonal IgM, kappa isotype control antibody, unconjugated.

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Catalog Number: (MSPP-04971)

Supplier: STEMCELL Technologies

Description: Complete kit including collagen, media, staining kit and chamber slides for human CFU-Mk assays.

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Catalog Number: (MSPP-781431006)

Supplier: STEMCELL Technologies

Description: Interleukin 1 beta (IL-1β) is synthesized as an inactive precursor protein or pro-IL-1β. This precursor is cleaved intracellularly by Caspase 1 (IL-1β convertase) to form the active form of the protein that is later secreted (Allan <i>et al.</i>). IL-1β binds to IL-1 receptor and activates intracellular signaling via the MAPK or NF-kB pathway. IL-1β is released by monocytes, tissue macrophages, and dendritic cells in response to infection or injury and induces expression of acute-phase proteins. It also promotes the infiltration of inflammatory and immunocompetent cells from the circulation into the extravascular space and affected tissues, by stimulating the expression of adhesion molecules on endothelial cells. IL-1β also affects other immune cells; for example, it co-stimulates T cell functions together with antigen or mitogen. It also stimulates Th17 differentiation and B cell proliferation in an IL-6-dependent manner. This product is animal component-free.

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