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Product Image-10075-672

Anti-GRIN2B Rabbit Polyclonal Antibody

Catalog Number: (10075-672)
Supplier: Prosci
Description: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression. Tyr1472 on NR2B is phosphorylated and this may lead to the increased expression of the NMDAR at the synapse that plays a role in synaptic plasticity.
Image Unavailable-TCB0853-005G

Nɑ-Benzoyl-L-arginine ethyl ester hydrochloride ≥98.0% (by titrimetric analysis)

Supplier: TCI America
Description: CAS Number: 2645-08-1
MDL Number: MFCD00012579
Molecular Formula: C15H22N4O3
Molecular Weight: 342.82
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Melting point (°C): 130
Specific rotation [a]20/D: -17 deg (C=2, H2O)

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Image Unavailable-TCC1283-100G

4-(Chloromethyl)benzoyl chloride ≥98.0% (by GC, titration analysis)

Catalog Number: (TCC1283-100G)
Supplier: TCI America
Description: CAS Number: 876-08-4
MDL Number: MFCD00053224
Molecular Formula: C8H6Cl2O
Molecular Weight: 189.04
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Flash Point (°C): 93
Freezing point (°C): 27

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Product Image-10109-730

Anti-EBP Rabbit Polyclonal Antibody

Catalog Number: (10109-730)
Supplier: Prosci
Description: EBP is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in EBP gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).Emopamil-binding protein (EBP) is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. EBP shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of EBP is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).
Image Unavailable-CA8.14167.0001

(2R)-(-)-1-Benzoyl-2-tert-butyl-3-methyl-4-imidazolidinone for synthesis, Sigma-Aldrich®

Catalog Number: (CA8.14167.0001)
Supplier: MilliporeSigma
Description: (2R)-(-)-1-Benzoyl-2-tert-butyl- 3-methyl-4-imidazolidinon, CAS Number: 101055-57-6, for synthesis.

SDS


Image Unavailable-TCT2020-250MG

2,3,4,6-Tetra-O-benzoyl-D-glucopyranose ≥90.0% (by HPLC)

Supplier: TCI America
Description: CAS Number: 64768-20-3
MDL Number: MFCD00066004
Molecular Formula: C34H28O10
Molecular Weight: 596.59
Purity/Analysis Method: >90.0% (HPLC)
Form: Crystal
Color: White
Melting point (°C): 122
Specific rotation [a]20/D: 73 deg (C=1, Dioxane)

SDS Certificates

Image Unavailable-77987-674

TRC rac Ketorolac 6-Benzoyl Isomer

Catalog Number: (77987-674)
Supplier: LGC Standards
Description: TRC rac Ketorolac 6-Benzoyl Isomer

New Product


Image Unavailable-TCB1911-005G

N-Benzoyl-L-tyrosine ≥98.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: CAS Number: 2566-23-6
MDL Number: MFCD01321140
Molecular Formula: C16H15NO4
Molecular Weight: 285.30
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Specific rotation [a]20/D: -77.5 deg (C=1, DMF)

SDS

Image Unavailable-M-1130.0025BA

Nɑ-Benzoyl-L-arginine ethyl ester hydrochloride

Supplier: Bachem Americas
Description: Sequence: Bz-Arg-OEt · HCl

Image Unavailable-10772-778

Human Recombinant PEDF (from E. coli)

Supplier: Peprotech
Description: PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties. It is a 50 kDa glycoprotein produced and secreted in many tissues throughout the body. A major component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells. In addition, PEDF is able to inhibit the activity of angiogenic factors, such as VEGF and FGF-2. The neuroprotective effects of PEDF are achieved through suppression of neuronal apoptosis induced by peroxide, glutamate, or other neurotoxins. The recent identification of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity ( Notari, I. et al. J Biol Chem., Vol. 281, 38022-38037 ) should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin. To date, PEDF-R is the only signaling receptor known to be used by a serpin family member. The unique range of PEDF activities implicate it as a potential therapeutic agent for the treatment of vasculature-related neurodegenerative diseases, such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR). PEDF also has the potential to be useful in the treatment of various angiogenesis-related diseases including a number of cancers. Recombinant Human PEDF is a 44.5 kDa non-glycosylated protein containing 400 amino acid residues.

Image Unavailable-TCB3239-5G

O-Benzoyl-N-methylhydroxylamine hydrochloride ≥98.0% (by HPLC, total nitrogen)

Supplier: TCI America
Description: CAS Number: 27130-46-7
Molecular Formula: C8H9NO2
Molecular Weight: 187.62
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Melting point (°C): 136

SDS Certificates

Image Unavailable-CAAAA18181-06

Nɑ-Benzoyl-L-arginine ethyl ester hydrochloride ≥98%

Supplier: Thermo Scientific Chemicals
Description: Nɑ-Benzoyl-L-arginine ethyl ester hydrochloride ≥98%

Certificates

Product Image-89417-788

Anti-MYOZAP Rabbit Polyclonal Antibody

Catalog Number: (89417-788)
Supplier: Prosci
Description: MYOZAP Antibody: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
Image Unavailable-TCT2641-25G

1,3,5-Tri-O-benzoyl-ɑ-D-ribofuranose ≥97.0% (by HPLC)

Supplier: TCI America
Description: CAS Number: 22224-41-5
MDL Number: MFCD00080818
Molecular Formula: C26H22O8
Molecular Weight: 462.45
Purity/Analysis Method: >97.0% (HPLC)
Form: Crystal
Color: White
Melting point (°C): 140
Specific rotation [a]20/D: 85 deg (C=1, CHCl3)
Lambda max.: 273 nm (MeOH)

SDS Certificates

Image Unavailable-TCB0102-001G

α-N-Benzoyl-L-argininamide hydrochloride monohydrate ≥98.0% (by titrimetric analysis)

Catalog Number: (TCB0102-001G)
Supplier: TCI America
Description: CAS Number: 4299-03-0 MDL Number: MFCD00035003 Molecular Formula: C13H19N5O2 Molecular Weight: 313.79 Purity/Analysis Method: <gt/>98.0% (T) Form: Crystal Specific rotation [a]20/D: 6.5 deg (C=4, H2O)

SDS


Image Unavailable-77978-310

TRC 3-Benzoyl-alpha-methylbenzeneacetonitrile

Catalog Number: (77978-310)
Supplier: LGC Standards
Description: TRC 3-Benzoyl-alpha-methylbenzeneacetonitrile

New Product


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