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Image Unavailable-76080-334

Anti-G3BP1Ser232 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76080-334)
Supplier: Bioss
Description: May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
Product Image-10751-998

Anti-LPIN1 Rabbit Polyclonal Antibody

Catalog Number: (10751-998)
Supplier: Prosci
Description: LPIN1 Antibody: LPIN1, also known as PAP1, is a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. LPIN1 is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in LPIN1 are associated with metabolic diseases such as type 2 diabetes and recurrent acute myoglobinuria and it is also a candidate for several human lipodystrophy syndromes.
Product Image-10749-022

Anti-PPM1D Rabbit Polyclonal Antibody

Catalog Number: (10749-022)
Supplier: Prosci
Description: Wild-type p53 induced phosphatase 1 (WIP1) / protein phosphatase magnesium-dependent 1 delta (PPM1D), a protein identified in the p53 DNA response pathway, is a member of the PP2C family of serine/threonine protein phosphatases which selectively inactivates p38 MAPK and dephosphorylates the ATM/ATR targets, Chk1 and p53. Studies have shown that it is overexpressed in human cancers and is involved in the regulation of multiple DNA damage signaling pathways. PPM1D deletion results in a reduction of T and B cell function and compromised cell division, rendering cells resistant to becoming cancerous and slowing tumor development.
Product Image-CA200064-480

BtsCI

Catalog Number: (CA200064-480)
Supplier: New England Biolabs (NEB)
Description: An E.coli strain that carries the BtsCI gene from Bacillus thermosphaericus (X. Pan).
Image Unavailable-CAPIPA5-18787

Anti-BPNT1 Goat Polyclonal Antibody

Catalog Number: (CAPIPA5-18787)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with mouse and rat based on sequence homology. BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Image Unavailable-76118-594

Anti-GIRK3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76118-594)
Supplier: Bioss
Description: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Image Unavailable-10089-908

Anti-MAGT1 Rabbit Polyclonal Antibody

Catalog Number: (10089-908)
Supplier: Proteintech
Description: MAGT1 is a mammalian Mg2+-selective transporter being required for cellular magnesium uptake and vertebrate embryonic development. It possesses five putative transmembrane (TM) regions with a cleavage site, a N-glycosylation site, and a number of phosphorylation sites. Western blot analysis revealed a 38-kD Magt1 protein in all mouse tissues as well as a 35-kD protein in some tissues.Recently mutations in MAGT1 has been found to be asscociated with a novel X-linked human immunodeficiency. The MAGT1 protein was undetectable in the patients’ cells by western blot or immunofluorescent cell surface staining(Nature 475, 471-6 ).
Product Image-470335-416

LaMotte® Total Hardness, Calcium, and Magnesium Water Test Kit

Catalog Number: (470335-416)
Supplier: LaMotte
Description: Precalibrated test tubes and labware give fast, accurate results on-site, in the classroom, or in the lab.
Image Unavailable-76099-860

Anti-HEAB Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Catalog Number: (76099-860)
Supplier: Bioss
Description: HEAB is a 425 amino acid nuclear protein that belongs to the Clp1 family. Utilizing magnesium, manganese or nickel as cofactors, HEAB participates in the phosphorylation of the 5'-hydroxyl groups of double- and single- stranded RNA and DNA. HEAB is a member of the tRNA splicing endonuclease complex, in conjunction with TSEN2, TSEN15, TSEN34 and TSEN54, and is also a member of the pre-mRNA cleavage complex II. The gene encoding HEAB maps to human chromosome 11q12.1 and mouse chromosome 2 D; mutations to this gene may lead to a reduced pre-mRNA cleavage activity. HEAB exists as two isoforms due to alternative splicing events.
Image Unavailable-10452-312

Anti-KCNJ3 Rabbit Polyclonal Antibody

Catalog Number: (10452-312)
Supplier: Bioss
Description: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Product Image-CA102969-122

SrfI

Supplier: New England Biolabs (NEB)
Description: An E. coli strain that carries the cloned SrfI gene from Streptomyces sp. (T.G. Simcox)

Image Unavailable-76118-592

Anti-GIRK3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76118-592)
Supplier: Bioss
Description: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Image Unavailable-75977-324

Anti-TOP1MT Mouse Monoclonal Antibody [clone: TOP1MT/488]

Supplier: Biotium
Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Product Image-55407-224

Photometry Reagents for 9000 Series Photometers, YSI

Catalog Number: (55407-224)
Supplier: YSI
Description: These photometry reagent starter kits for the 9000 Series Photometers include reagent tablets, instructions, and accessories for 50 tests

SDS


Image Unavailable-75977-332

Anti-TOP1MT Mouse Monoclonal Antibody (Biotin) [clone: TOP1MT/488]

Supplier: Biotium
Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Product Image-89417-840

Anti-SIK1 Rabbit Polyclonal Antibody

Catalog Number: (89417-840)
Supplier: Prosci
Description: SIK1 Antibody: Salt-inducible kinase 1 (SIK1), also known as SNF1LK or MSK, plays a role in histone modification and G2/M cell cycle regulation. It is a 783 amino acid protein that contains one UBA domain and belongs to the Ser/Thr protein kinase family (AMPK subfamily). Localized to both the nucleus and the cytoplasm, SIK1 is a class II HDAC kinase that uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation.
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