You Searched For: Gly-Arg-AMC

Catalog Number: (10490-492)

Supplier: Bioss

Description: Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor X (Stuart Prower factor, FX, F10) is a vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. The mature form of Factor X (Factor X A) is generated by Factor IX A- or Factor VII A-mediated cleavage at the tripeptide sequence, Arg-Lys-Arg, to yield a disulfide linked dimer. Together with the cofactor Factor V A and Ca2+ on the surface of platelets or endothelial cells, Factor X A coordinates as part of the prothrombinase complex, which mediates proteolysis of Prothrombin into active Thrombin. Mutations at the Factor X locus resulting in Factor X deficiencies can contribute to hemorrhagic diathesis.

Catalog Number: (10488-696)

Supplier: Bioss

Description: Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor X (Stuart Prower factor, FX, F10) is a vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. The mature form of Factor X (Factor X A) is generated by Factor IX A- or Factor VII A-mediated cleavage at the tripeptide sequence, Arg-Lys-Arg, to yield a disulfide linked dimer. Together with the cofactor Factor V A and Ca2+ on the surface of platelets or endothelial cells, Factor X A coordinates as part of the prothrombinase complex, which mediates proteolysis of Prothrombin into active Thrombin. Mutations at the Factor X locus resulting in Factor X deficiencies can contribute to hemorrhagic diathesis.

Supplier: Thermo Scientific Chemicals

Description: Hippuric acid 98%

Certificates

Supplier: Bachem Americas

Description: Sequence: Boc-Sar-OH

Supplier: TCI America

Description: CAS Number: 1234-35-1
MDL Number: MFCD00001762
Molecular Formula: C14H20N4O4
Molecular Weight: 308.34
Purity/Analysis Method: >97.0% (T)
Form: Crystal
Melting point (°C): 173
Specific rotation [a]20/D: -10 deg (C=5.5, 0.2mol/L HCl)

SDS

Supplier: Bachem Americas

Description: The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication. Irreversible inhibitor of streptopain.

Supplier: Thermo Scientific Chemicals

Description: Powder

Certificates

Supplier: TCI America

Description: CAS Number: 513-29-1
MDL Number: MFCD00036426
Molecular Formula: C2H5NO2
Molecular Weight: 107.76
Purity/Analysis Method: >98.0% (N,T)
Form: Crystal

SDS

Supplier: Bachem Americas

Description: Please see also 5-(Pentafluorobenzoylamino)fluorescein (M-2375), a sensitive fluorogenic substrate for the determination of glutathione S-transferase (GST) activity and glutathione (GSH) concentration, and the carba-analog of GSH, ophthalmic acid, H-3145.

Catalog Number: (TCF0421-5G)

Supplier: TCI America

Description: CAS Number: 3154-51-6
MDL Number: MFCD00014125
Molecular Formula: C5H9NO3
Molecular Weight: 131.13
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Specific Gravity (20/20): 1.15

Certificates

Catalog Number: (CA80053-414)

Supplier: MilliporeSigma

Description: Nω-Nitro-L-arginine methyl ester hydrochloride, Calbiochem®

Certificates

Catalog Number: (10671-382)

Supplier: Bioss

Description: DPP6 is a Type-II serine proteinase of the clan SC. The clan SC proteinases have a catalytic triad of Ser-Asp-His, and like other Serine proteinases, the active site serine is in a Gly-Xaa-Ser-Xaa -Gly orientation. DPP6 has an Asp instead of Ser in the catalytic site. DPP6 is a member of a broader family of dipeptidyl peptidases including DPP4, FAP/Seprase, DPP2, DPP8, DPP9, DPP10, which have differing substrate specificity and tissue localizations. The surface-bound DPP6 is a homodimer, and cleavage of in the stalk region releases a shed form of DPP6. The shed is the form found in serum. DPP6 has been found in highest abundance in the brain, but also in the kidney, liver and lung.

Catalog Number: (10665-512)

Supplier: Bioss

Description: DPP6 is a Type-II serine proteinase of the clan SC. The clan SC proteinases have a catalytic triad of Ser-Asp-His, and like other Serine proteinases, the active site serine is in a Gly-Xaa-Ser-Xaa -Gly orientation. DPP6 has an Asp instead of Ser in the catalytic site. DPP6 is a member of a broader family of dipeptidyl peptidases including DPP4, FAP/Seprase, DPP2, DPP8, DPP9, DPP10, which have differing substrate specificity and tissue localizations. The surface-bound DPP6 is a homodimer, and cleavage of in the stalk region releases a shed form of DPP6. The shed is the form found in serum. DPP6 has been found in highest abundance in the brain, but also in the kidney, liver and lung.

Supplier: TCI America

Description: CAS Number: 1504-41-2
MDL Number: MFCD00038187
Molecular Formula: C8H16N2O3
Molecular Weight: 188.23
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Melting point (°C): 227

SDS

Supplier: TCI America

Description: CAS Number: 31954-27-5
MDL Number: MFCD00038267
Molecular Formula: C8H15NO4
Molecular Weight: 189.21
Purity/Analysis Method: >98.0% (N)
Form: Clear Liquid
Flash Point (°C): 109
Specific Gravity (20/20): 1.08

SDS

Supplier: Bachem Americas

Description: Fluorescent substrate for carboxypeptidase M. Because the substrate and the cleavage product Dansyl-Ala-OH are equally fluorescent (λex = 340 nm; λem = 495 nm), the product has to be extracted with chloroform. The uncleaved substrate remains in the aqueous phase (at acidic pH).