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Catalog Number: (76108-788)
Supplier: Bioss
Description: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. Gcom1 (GRINL1A complex locus protein 1), also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor. Gcom1 is expressed in small intestine, lung, liver, heart, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons. There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events.


Catalog Number: (89358-682)
Supplier: Genetex
Description: Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules.


Catalog Number: (ABCA_AB263882-1X96)
Supplier: Abcam
Description: Mouse AST ELISA kit is a single-wash, 90-minute SimpleStep ELISA® assay designed for the quantification of mouse aspartate aminotransferase (AST/cAspAT) with a sensitivity of 39 pg/mL. The assay employs a simple Mix-Wash-Read protocol with just one incubation and wash step. - Colorimetric sandwich ELISA with a 450 nm readout; compatible with any standard plate reader - Available in different formats to meet various throughput needs, including 384-well plates for higher throughput - Design your own immunoassay: we also offer the conjugation-ready, carrier-dree antibody pair. - Cited in over 25 publications.

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Catalog Number: (103010-660)
Supplier: Anaspec Inc
Description: Cathepsin E is a non-lysosomal aspartic proteinase of the pepsin superfamily, playing an important role in host defense against cancer cells in addition to it’s roles in protein degradation, antigen processing etc


Catalog Number: (89278-806)
Supplier: Genetex
Description: Mouse Monoclonal antibody to CAD (carbamoyl-phosphate synthetase 2 aspartate transcarbamylase and dihydroorotase) Clone: 36A349 Purity: Protein G purified Species Reactivity: Human Mouse Rat Tested Applications: WB Pkg Size: 100 ug


Catalog Number: (10110-678)
Supplier: Prosci
Description: This gene (Gcom1) is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts. The GRINL1A gene uses a downstream promoter for transcription and also has multiple alternatively spliced variants.This gene (Gcom1) is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts. The GRINL1A gene uses a downstream promoter for transcription and also has multiple alternatively spliced variants.


Catalog Number: (CAPIPA5-13553)
Supplier: Thermo Scientific
Description: ASPN belongs to a family of leucine-rich repeat (LRR) proteins associated with the cartilage matrix. The name asporin reflects the unique aspartate-rich N terminus and the overall similarity to decorin.


Supplier: MilliporeSigma
Description: A cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine, and serine proteases as well as aminopeptidases
Supplier: MilliporeSigma
Description: A cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine, and serine proteases as well as aminopeptidases.
Catalog Number: (10473-994)
Supplier: Bioss
Description: ATE1, also known as arginyltransferase 1, is an enzyme that is involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. There are two named isoforms.


Catalog Number: (75794-022)
Supplier: Prosci
Description: TRAIL-R1 (DR4; CD261) is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.


Catalog Number: (10391-984)
Supplier: Bioss
Description: SLC25A13 is a member of the mitochondrial carrier family. It contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. It catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in the SLC25A13 gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.


Catalog Number: (76100-776)
Supplier: Bioss
Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).


Catalog Number: (CA71003-268)
Supplier: G-Biosciences
Description: G-Biosciences' Immobilized Pepstatin is for the purification of cathepsins, pepsin, bacterial aspartic proteases, HIV proteases and other molecules that bind pepstatin.

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Catalog Number: (CA10817-982)
Supplier: Biolegend
Description: NMDAR1, Monoclonal Antibody, Purified, Clone: R1JH, Species reactivity: Rat, Mouse, Immunogen: raised against a fusion protein from aa1-564 of rat NMDA NR1. It is sold as lyophilized TCS, Synonyms: N-methyl-D-aspartate receptor channel, subunit zeta-1, Size: 15 ug


Catalog Number: (76100-774)
Supplier: Bioss
Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).


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