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Catalog Number: (TCC2645-5G)
Supplier: TCI America
Description: CAS Number: 352535-83-2
MDL Number: MFCD05664225
Molecular Formula: C6H5BClFO2
Molecular Weight: 174.36
Form: Crystal
Color: White

SDS


Catalog Number: (10496-214)
Supplier: Bioss
Description: CHPT1, also known as AAPT1-like protein and Diacylglycerol cholinephosphotransferase 1, is a 406 amino acid multi-pass membrane protein that is localized to the golgi apparatus. By catalyzing the phosphatidylcholine biosynthesis from CDP-choline, it plays an essential role in the formation and maintenance of vesicular membranes. CHPT1 is most abundant in testis, as well as small intestine, heart, colon, spleen and prostate. Expression of CHPT1 is increased in cancerous breast cells as compared to normal breast cell lines and it has been determined that the CHPT1 gene exhibits mutations within the cancerous cells. Interestingly, exposure to mustard gas significantly decreases CHPT1 gene expression and activity, an event that may play an important role in the development of acute respiratory distress syndrome (ARDS). There are two isoforms of CHPT1 that are produced as a result of alternative splicing events.


Catalog Number: (CAMB-041)
Supplier: Rockland Immunochemical


Supplier: Peprotech
Description: VEGF-D, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-D is highly expressed in the lung, heart, small intestine and fetal lung, and at lower levels in the skeletal muscle, colon, and pancreas. It forms cell surface-associated, non-covalent, disulfide-linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-D may play a role in the formation of the venous and lymphatic vascular systems. It also participates in the growth and maintenance of differentiated lymphatic endothelium in adults. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant Human VEGF-D is a 26.2 kDa, non-disulfide linked, homodimeric protein consisting of two 117 amino acid polypeptide chains. Due to glycosylation, the protein migrates as a 20.0-22.0 kDa band by SDS-PAGE analysis under non-reducing conditions.

Supplier: TCI America
Description: CAS Number: 533-18-6
MDL Number: MFCD00053704
Molecular Formula: C9H10O2
Molecular Weight: 150.18
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 208
Specific Gravity (20/20): 1.05
Supplier: MilliporeSigma
Description: Biosynthesis
Catalog Number: (10492-924)
Supplier: Bioss
Description: BAR proteins are characterized by a common N-terminal BAR (bin, amphiphysin and Rvs161/167) domain and are recognized as adaptor proteins that are involved in many cellular processes. BIN1 and BIN2 are BAR proteins that share 61% sequence similarity. BIN1 (Bridging integrator 1) is a ubiquitously expressed regulatory protein for synaptic vesicle endocytosis. BIN1 also interacts with the transcription factors c-Myc and MyoD, potentially functioning as a tumor suppressor. BIN2, also known as Breast cancer-associated protein 1, is a 565 amino acid protein that interacts with BIN1. In contrast to BIN1, BIN2 lacks tumor suppressor features as well as a c-Myc interacting region. BIN2 shows preferred expression in tissues of hematopoietic origin, with high levels found in spleen, thymus, colon, placenta, lymphoid and granulocytic cells. There are two isoforms of BIN2 that are produced as a result of alternative splicing events.


Supplier: TCI America
Description: CAS Number: 329214-79-1
MDL Number: MFCD03084758
Molecular Formula: C11H16BNO2
Molecular Weight: 205.06
Purity/Analysis Method: >97.0% (GC,T)
Form: Crystal
Color: White
Melting point (°C): 104
Catalog Number: (10072-898)
Supplier: Prosci
Description: APRIL, a member of the TNF superfamily, is expressed in monocytes, macrophages, certain transformed cell lines, certain cancers of colon, and lymphoid tissues. APRIL, along with another TNF family member, BAFF, compete for two receptors, TACI and BCMA. ARPIL has the ability to stimulate proliferation of various tumor cell lines including Jurkat T cells and MCF-7 carcinoma cells. Like BAFF, APRIL also stimulates the proliferation of B and T cells. The human APRIL gene codes for at least four alternatively spliced transcriptional variants, which give rise to different isoforms of the APRIL precursor protein. All isoforms can be cleaved by the protease, furin, to release a soluble C-terminal fragment, which comprises the TNF like receptor binding of the APRIL precursor. Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues.


Supplier: MilliporeSigma
Supplier: TCI America
Description: CAS Number: 122-88-3
MDL Number: MFCD00004305
Molecular Formula: C8H7ClO3
Molecular Weight: 186.59
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 158
Supplier: TCI America
Description: CAS Number: 53088-68-9
MDL Number: MFCD00800679
Molecular Formula: C9H9ClO2
Molecular Weight: 184.62
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Specific Gravity (20/20): 1.20

SDS

Catalog Number: (CA80503-238)
Supplier: MilliporeSigma
Description: Potassium acetate, Molecular Biology Grade, Calbiochem®, Millipore®

Supplier: TCI America
Description: CAS Number: 137504-86-0
MDL Number: MFCD01319010
Molecular Formula: C6H5BClFO2
Molecular Weight: 174.36
Form: Crystal
Color: White
Melting point (°C): 144

SDS

Supplier: Bachem Americas
Description: Highly efficient coupling additive, a safer, non-explosive alternative to HOBt.

Supplier: Biotium
Description: This MAb reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40 kDa. Its epitope maps between amino acid 312-335. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

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