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Product Image-10751-442

Anti-TMPRSS11A Chicken Polyclonal Antibody

Catalog Number: (10751-442)
Supplier: Prosci
Description: ECRG1 Antibody: Epidermal type-II transmembrane serine protease (ECRG1), also known as TMPRSS11A, is a member of a novel esophageal cancer-related gene family. It is a type-II transmembrane serine protease which may play a role in cellular senescence. It is expressed in esophagus, liver, colon and lung. Overexpression of ECRG1 inhibits cell growth and induces G1 cell cycle arrest. It is down-regulated in esophagus cancers (EC) and might play important roles in the initiation and progression of EC.
Product Image-470225-674

Sodium Acetate Anhydrous

Supplier: Ward's Science
Description: CAS Number: 127-09-3
Formula: NaC2H3O2
Density: 1.53 g/mL
Freezing Point: 324°C
Solubility: Water and Alcohol
Synonyms: Acetic Acid Sodium Salt
Shelf Life: 12 Months

SDS

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(3-Phenoxyphenyl)acetic acid 98%

Supplier: Thermo Scientific Chemicals
Description: (3-Phenoxyphenyl)acetic acid 98%

Certificates

Image Unavailable-75963-758

Anti-MUC1 Mouse Monoclonal Antibody (CF568) [clone: MUC1/967]

Supplier: Biotium
Description: This MAb recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this MAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200 kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the MAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This MAb reacts with both normal and malignant epithelia of various tissues including breast and colon.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Image Unavailable-CAAAAA13858-14

(4-Hydroxy-3-nitrophenyl)acetic acid 99%

Supplier: Thermo Scientific Chemicals
Description: (4-Hydroxy-3-nitrophenyl)acetic acid 99%

Certificates

Image Unavailable-CAAAB22872-06

(2-Chloro-4-fluorophenyl)acetic acid 97%

Supplier: Thermo Scientific Chemicals
Description: (2-Chloro-4-fluorophenyl)acetic acid 97%

Certificates

Image Unavailable-CAAAAB25434-06

2-Formylphenylboronic acid 97%

Supplier: Thermo Scientific Chemicals
Description: 2-Formylphenylboronic acid 97%

Certificates

Image Unavailable-75962-878

Anti-MUC6 Mouse Monoclonal Antibody (CF640R) [clone: CLH5]

Supplier: Biotium
Description: The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Image Unavailable-TCE1187-5G

3-(Ethoxycarbonyl)-4-fluorophenylboronic acid (contains varying amounts of Anhydride)

Supplier: TCI America
Description: 3-(Ethoxycarbonyl)-4-fluorophenylboronic Acid, CAS Number: 874219-36-0, Molecular Formula: C9H10BFO4, Molecular Weight: 211.98, Synonyms: 3-(Ethoxycarbonyl)-4-fluorobenzeneboronic Acid, Size: 1G

Image Unavailable-75789-376

Human Recombinant CD87 (from Cells)

Catalog Number: (75789-376)
Supplier: Prosci
Description: The Urokinase Type Plasminogen Activator (uPA) receptor (uPAR) is a widely expressed receptor for urokinase plasminogen activator (uPA) and pro-uPA. uPAR / CD87 is a highly glycosylated, 55-60kDa integral membrane protein linked to the plasma membrane by a glycosylphosphatidylinositol (GPI) anchor. uPAR is expressed by T-cells, NK cells, monocytes, and neutrophils as well as non-hematopoietic cells that include vascular endothelial cells, fibroblasts, smooth muscle cells, keratinocytes, placental trophoblasts, hepatocytes, and a wide variety of tumor cells (including breast, colon, and prostate carcinoma, melanoma). It plays a critical role in the regulation of cell-surface plasminogen activation in physiological and pathological conditions, and it is also involved in cellular adhesion, the transmission of extracellular signals across the plasma membrane and the subsequent regulation of gene expression. uPAR has been implicated in several biological processes including angiogenesis, monocyte migration, cancer metastasis, trophoblast implantation, and wound healing. Human uPAR is encoded as a 313 amino acid residue polypeptide, excluding a 22 residue signal peptide and shows 60-70% similarity with the murine uPAR amino acid sequence although binding of uPA to uPAR shows strong species specificity.
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1-Pyreneboronic acid (contains varying amounts of Anhydride)

Supplier: TCI America
Description: CAS Number: 164461-18-1
Molecular Formula: C16H11BO2
Molecular Weight: 246.07
Form: Crystal
Color: White
Melting point (°C): 251

SDS Certificates

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4-Butoxyphenylboronic acid (contains varying amounts of Anhydride)

Supplier: TCI America
Description: 4-Butoxyphenylboronic Acid, Cas no. 105365-51-3, Molecular formula: C10H15BO3, Form: Crystal- Powder, Colour: White - Almost white, Synonyms: 4-Butoxybenzeneboronic Acid (contains varying amounts of Anhydride), Size: 1G

SDS

Image Unavailable-76120-624

Anti-BIN2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76120-624)
Supplier: Bioss
Description: BAR proteins are characterized by a common N-terminal BAR (bin, amphiphysin and Rvs161/167) domain and are recognized as adaptor proteins that are involved in many cellular processes. BIN1 and BIN2 are BAR proteins that share 61% sequence similarity. BIN1 (Bridging integrator 1) is a ubiquitously expressed regulatory protein for synaptic vesicle endocytosis. BIN1 also interacts with the transcription factors c-Myc and MyoD, potentially functioning as a tumor suppressor. BIN2, also known as Breast cancer-associated protein 1, is a 565 amino acid protein that interacts with BIN1. In contrast to BIN1, BIN2 lacks tumor suppressor features as well as a c-Myc interacting region. BIN2 shows preferred expression in tissues of hematopoietic origin, with high levels found in spleen, thymus, colon, placenta, lymphoid and granulocytic cells. There are two isoforms of BIN2 that are produced as a result of alternative splicing events.
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(3-Fluorophenyl)acetic acid ≥98.0% (by GC, titration analysis)

Supplier: TCI America
Description: CAS Number: 331-25-9
MDL Number: MFCD00004331
Molecular Formula: C8H7FO2
Molecular Weight: 154.14
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Boiling point (°C): 125
Melting point (°C): 47
Flash Point (°C): 110

SDS Certificates

Image Unavailable-TCD4690-1G

2,6-Dimethoxy-3-pyridineboronic acid (contains varying amounts of Anhydride)

Supplier: TCI America
Description: CAS Number: 221006-70-8
MDL Number: MFCD03788239
Molecular Formula: C7H10BNO4
Molecular Weight: 182.97
Form: Crystal
Color: White
Melting point (°C): 109

SDS

Image Unavailable-10072-894

Human Recombinant Rank Receptor (soluble) (from E. coli)

Catalog Number: (10072-894)
Supplier: Prosci
Description: RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate naïve T cell proliferation and to promote the survival of RANK + T cells. RANK is also expressed in a variety of tissues including skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. The RANK/RANKL interaction is important in the regulation of osteoclastogenesis and in dendritic-cell-mediated T cell immune responses. Impairments in RANK signaling have been implicated in the induction of expansile osteolysis and Paget disease of bone (PDB2). Recombinant human sRANK receptor is a 19.3 kDa polypeptide containing the TNFR homologous cysteine rich portion of the extracellular domain of RANK receptor (175 amino acid residues).
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