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Product Image-10091-060

Anti-neuromedin B Rabbit Polyclonal Antibody

Catalog Number: (10091-060)
Supplier: Proteintech
Description: Neuromedin B (NMB) is a bombesin-like peptide, which inhibits food intake and modulates stress-related behaviour. It exerts its function via NMB receptor (NMB-R). NMB is encoded in a 76-amino acid precursor. The mature NMB was reported to be a 10-amino-acid peptide, giving two bands of 1.2 kDa and 1.5 kDa in western blotting. NMB is expressed in brain, gastrointestinal tract, pancreas, adrenals, and adipose tissue. It regulates exocrine and endocrine secretions, cell growth, body temperature and blood pressure and glucose level in vivo.
Image Unavailable-10072-668

Human Recombinant TIMP1 (from E. coli)

Catalog Number: (10072-668)
Supplier: Prosci
Description: TIMP1 is an extracellular inhibitor of MMPs (see above) including MMP1, 2, 3, 7, 8, 9, 10, 11, 12, 13, and 16. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP1 can also act through an MMP-independent mechanism to promote erythropoiesis by stimulating proliferation and differentiation of erythroid progenitors. Recombinant human TIMP-1 is a 20.6 kDa protein containing 184 amino acid residues.
Image Unavailable-TCA2086-1G

2-Allenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ≥95.0% (by GC, titration analysis)

Supplier: TCI America
Description: CAS Number: 865350-17-0
MDL Number: MFCD09265121
Molecular Formula: C9H15BO2
Molecular Weight: 166.03
Purity/Analysis Method: >95.0% (GC,T)
Form: Clear Liquid
Boiling point (°C): 81
Flash Point (°C): 66
Specific Gravity (20/20): 0.94
Storage Temperature: 0-10°C

SDS

Product Image-CA76515-246

CrossLab Peristaltic Pump Tubing for ICP-MS, Agilent Technologies

Supplier: AGILENT TECHNOLOGIES, INC (CSD) CA
Description: Agilent offers a range of ICP-MS peristaltic pump tubing, in suitable materials for your application.

Image Unavailable-95035-694

Sodium L(+)-ascorbate ≥99.0%, powder USP

Supplier: Spectrum Chemicals
Description: Sodium Ascorbate, Powder, USP is used to prevent or treat low levels of vitamin C in people who do not get enough of the vitamin from their diets. All Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities

Certificates

Image Unavailable-10168-284

Anti-ATG12 Mouse Monoclonal Antibody [clone: GT948]

Catalog Number: (10168-284)
Supplier: Genetex
Description: Mouse Monoclonal antibody [GT948] to ATG12 (ATG12 autophagy related 12 homolog (S. cerevisiae))
Image Unavailable-10406-120

Anti-ADAM12 Rabbit Polyclonal Antibody

Catalog Number: (10406-120)
Supplier: Bioss
Description: ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNF?(tumor necrosis factor ?, and modulation of the neurogenic function of Notch and Delta (1-3). ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (Integrin ligand), a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail (1-3). ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone, and muscle, and catalyze proteolysis, adhesion, fusion, and intracellular signaling (3). ADAM 12 (Meltrin-a) is produced as 2 differentially spliced isoforms, a 718 amino acid secreted form (ADAM12S) and a 881 amino acid membrane-bound form (ADAM12L), and is involved in egg-sperm fusion (4-6).
Image Unavailable-CAAAH33334-06

Methyl-2-hydroxynicotinate 97%

Supplier: Thermo Scientific Chemicals

Certificates

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N,N-Dimethylformamide ≥99.9% (by GC), Supelco®

Supplier: MilliporeSigma
Description: Flammable.

SDS Certificates

Product Image-CAAA43997-K2

N,N-Dimethylformamide, anhydrous ≥99.8%, ChemSeal™

Supplier: Thermo Scientific Chemicals
Description: N,N-Dimethylformamide, anhydrous ≥99.8%, ChemSeal™

Certificates

Product Image-89415-436

Anti-CASP12 Rabbit Polyclonal Antibody

Catalog Number: (89415-436)
Supplier: Prosci
Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.
Image Unavailable-10459-158

Anti-TMEM263 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10459-158)
Supplier: Bioss
Description: C12orf23 (chromosome 12 open reading frame 23), also known as FLJ11721, FLJ13959 or MGC17943, is a 116 amino acid multi-pass membrane protein belonging to the UPF0444 family. C12orf23 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a number of skeletal deformities, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.
Image Unavailable-103001-346

Human Recombinant MMP-12 (from E. coli)

Supplier: Anaspec Inc
Description: Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. MMP-12 (macrophage elastase) is involved in smoke-induced emphysema, tumor and other diseases. MMP-12 is secreted as a 54-kDa zymogen and becomes the mature 45-kDa active form after proteolytic cleavage. MMP-12 has a broad range of substrates, including α-1 proteinase inhibitor, α-2 antiplasmin, plasminogen activator inhibitor-2, collagen IV, laminin, fibronectin, elastin, but not interstitial collagens.

The sequence (Accession # NP_002417) corresponding to the catalytic domain (aa 106-267) of Human MMP-12 was expressed in E. coli. The recombinant human MMP-12 was purified from bacterial lysate and refolded using proprietary technique. The molecular weight of the recombinant Human MMP-12 Catalytic Domain is 18 kDa.

Image Unavailable-TCA0659-500G

m-Tolyl acetate ≥99.0%

Supplier: TCI America
Description: CAS Number: 122-46-3
MDL Number: MFCD00041910
Molecular Formula: C9H10O2
Molecular Weight: 150.18
Purity/Analysis Method: >99.0% (GC)
Form: Clear Liquid
Boiling point (°C): 212
Melting point (°C): 12
Flash Point (°C): 95
Specific Gravity (20/20): 1.05

SDS Certificates

Image Unavailable-10477-524

Anti-CCDC38 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10477-524)
Supplier: Bioss
Description: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC38 (coiled-coil domain containing 38) is a 563 amino acid protein encoded by a gene that maps to human chromosome 12q23.1. Encoding over 1,100 genes, chromosome 12 comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Image Unavailable-10779-766

Human Recombinant IL-23 (from (BTI-Tn-5B1-4) Hi-5 Insect Cells)

Supplier: Peprotech
Description: IL-23 is a proinflammatory, heterodimeric protein composed of two subunits: a unique p19 subunit, and a p40 subunit that is shared with IL-12. IL-23 is secreted by activated dendritic cells and macrophages, and signals though a receptor comprised of IL-23R complexed with IL-12Rβ2. IL-23 has been shown to enhance proliferation of memory T cells. It also stimulates the production of IFN-γ in NK cells, induces IL-17 production, and drives Th17-mediated responses. Recombinant Human IL-23 is a 53.5 kDa, heterodimeric protein consisting of the two subunits, p19 (170 amino acids) and p40 (306 amino acids).

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