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Catalog Number: (I-1420.0250BA)

Supplier: Bachem Americas

Description: Sequence: H-Ile-AMC
Synonym(s): H-Ile-MCA (free base)

Supplier: Bachem Americas

Description: Endothelins are peptides with exceptional vasoconstrictor potency. They play an important role in intercellular communications.

Supplier: Bachem Americas

Description: Please see also α-MSH (corresponds to acetyl-ACTH (1-13) amide, H-1075), α-MSH (free acid) (acetyl-ACTH (1-13), H-1070), and (Des-acetyl)-α-MSH (H-4390). Wied: Pituitary Adrenal System Hormones and Behaviour. Symposium on Developments in Endocrinology (1976) / Anon.: ACTH and Related Peptides: Structure, Regulation, and Action. Ann. N.Y. Acad. Sci. 297, 1 (1977) / A.V.Schally: Aspects of Hypothalamic Regulation of the Pituitary Gland. Science 202, 18 (1978) / R.Schwyzer: Studies on Polypeptide Receptors. A Critical View on the Mechanism of ACTH Action. Bull. Schweiz. Acad. Med. Wiss. 34, 263 (1978).

Supplier: Bachem Americas

Description: Reaction of the dipeptide KY with diethylenetriaminepentaacetic (DTPA) cyclic anhydride yielded monovalent and bivalent haptens. In vitro, the antibody conjugate (which was prepared by coupling F(ab’)2 or Fab’ fragments of an antibody specific for the human high molecular weight melanoma associated antigen to Fab’ fragments of an antibody specific for In-DTPA complexes) mediated binding of the ¹¹¹In-labeled haptens to melanoma cells. In vivo, it allowed specific localization of the haptens in A375 tumors. The bivalent hapten exhibited much higher efficiency at targeting ¹¹¹In onto cells, both in vitro and in vivo.

Supplier: Bachem Americas

Description: Triglycine to hexaglycine.

Supplier: Bachem Americas

Description: Sequence: MEGA-9
Synonym(s): Nonanoyl-N-methylglucamide

Supplier: Bachem Americas

Description: Sequence: Z-OSu
Synonym(s): N-(Benzyloxycarbonyloxy)succinimide

Catalog Number: (G-4145.0250BA)

Supplier: Bachem Americas

Description: A good substrate for carboxypeptidases B and N.

Supplier: Bachem Americas

Description: Potent and long-acting CRF antagonist.

Supplier: Bachem Americas

Description: These short peptides act as angiotensin I-converting enzyme (ACE) inhibitors. See also Phe-Tyr (G-2955) and the subfamilies 'Bradykinin-Potentiating Peptide (BPP)' and 'Angiotensin I-Converting Enzyme (ACE, ACE2) Inhibitors'.

Supplier: Bachem Americas

Description: Cell-permeable, irreversible inhibitor of paracaspase MALT1. The inhibitor was based on the sequence of a published optimal tetrapeptide substrate for the A. thaliana metacaspase AtMC9.

SDS

Supplier: Bachem Americas

Description: F2L is an acetylated peptide corresponding to an N-terminal fragment of the human heme-binding protein. Ac-MLGMIKNSLFGSVETWPWQVL acts specifically through the FPR-like receptor (FPRL) 2 promoting calcium mobilization and chemotaxis in dendritic cells and monocytes. In neutrophils, F2L inhibited FPR and FPRL1-mediated signaling.

SDS

Supplier: Bachem Americas

Description: High affinity ligand for all five somatostatin receptors (sst1-sst5). In AtT-20 mouse anterior pituitary tumor cells which mainly express sst2 and sst5 receptors the binding affinity of this somatostatin analog was found to be higher than that of somatostatin-14 (H-1490) and octreotide (H-5972). In a model of epileptogenesis, however, KE 108 did not exhibit antiepileptic activity suggesting that the high potency and efficacy of a synthetic ligand to all known somatostatin receptors may not reproduce entirely the effects of the natural ligand.

Catalog Number: (H-9985.0005BA)

Supplier: Bachem Americas

Description: The octapeptide ALILTLVS is produced by Streptococcus faecalis donor strains harboring bacteriocin plasmid pPD1. It inhibits the activity of sex pheromone cPD1. The non-polar peptide iPD1 is also used for calibration in mass spectrometry.

Catalog Number: (H-9940.1000BA)

Supplier: Bachem Americas

Description: Iberiotoxin (IbTx), from the venom of the scorpion Buthus tamulus, shows 68% sequence homology with charybdotoxin, another scorpion-derived peptidyl toxin. Although these two toxins both inhibit the high conductance Ca²⁺ activated K⁺ channel, they appear to bind at different sites on the channel and modulate channel activity by different mechanisms. Thus, iberiotoxin can be used to selectively study the function of the high conductance Ca²⁺ activated K⁺ channel.

Catalog Number: (H-3580.0250BA)

Supplier: Bachem Americas

Description: Lipolytic peptide, corresponds to pTH (12-14).