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Supplier: Enzo Life Sciences
Description: Antibiotic

Catalog Number: (89158-178)
Supplier: Enzo Life Sciences
Description: A novel geldanamycin fluorescent probe that may be used in a fluorescence polarization assay for HSP90 inhibitors. May also be used for detection of cell surface HSP90.


Catalog Number: (89158-860)
Supplier: Enzo Life Sciences
Description: Chromomycin A3 is a GC-specific DNA ligand which inhibits transcription


Catalog Number: (89141-658)
Supplier: Enzo Life Sciences
Description: Species Independent


Catalog Number: (89141-668)
Supplier: Enzo Life Sciences
Description: For the quantitative determination of hydrogen peroxide in culture supernatants and cell lysates from any species.


Supplier: Enzo Life Sciences
Description: Potent and highly selective calcium ionophore

Catalog Number: (89141-230)
Supplier: Enzo Life Sciences
Description: For the measurement of glutathione peroxidase in cell lysates, plasma, and tissue from any species.


Catalog Number: (89150-236)
Supplier: Enzo Life Sciences
Description: Co-metabolite of nemadectin


Catalog Number: (89141-776)
Supplier: Enzo Life Sciences


Supplier: Enzo Life Sciences
Description: Competitively inhibits the generation of NO from arginine and is a useful tool for inhibition of NO mediated effects. In vitro, L-NMMA inhibits relaxation of rat aorta rings induced by acetylcholine (IC50=9.5µM). In vivo, it causes a dose dependent increase in mean arterial blood pressure in anesthetized rats (EC50=16.7mg/kg).

Catalog Number: (89141-754)
Supplier: Enzo Life Sciences
Description: For the quantitative determination of total Nitric Oxide in culture supernatants, plasma, serum, saliva, and urine from any species


Supplier: Enzo Life Sciences
Description: White to off-white powder

Catalog Number: (89154-072)
Supplier: Enzo Life Sciences
Description: Host: Rat, Isotype: IgG1


Catalog Number: (89161-022)
Supplier: Enzo Life Sciences
Description: This peptide sequence, ARRKRKGSFFYGG, was selected from a peptide library for optimal phosphorylation by protein kinase C delta (PKCdelta).


Catalog Number: (89141-478)
Supplier: Enzo Life Sciences
Description: The octapeptide circulatory hormone Angiotensin II is a critical regulator of cardiovascular homeostasis formed in blood, with dual function in tissues of the brain, kidney, heart, and vasculature as an autocrine/paracrine growth hormone. The actions of angiotensin II are mediated by type one (AT1) and type two (AT2) angiotensin II receptors, members of the seven-transmembrane Gprotein coupled receptor (GPCR) family. AT1 receptors couple predominantly with Gq/11 alpha subunits, and signal through phospholipases C, D, and A2, inositol phosphates, and calcium channels, as well as a variety of serine/threonine and tyrosine kinases. AT1 expression is greatest in vascular smooth muscle, liver, kidney, adrenal cortex, brain, and lung, and is primarily responsible for the physiological effects of angiotensin II, including regulation of arterial blood pressure, electrolyte and water balance, thirst, hormone secretion, and renal function. The AT2 receptor displays approximately 30% identity to the AT1 receptor, and is highly expressed during embryonic development. AT2 expression in adult tissue is limited to the adrenal medulla, brain, and reproductive tissues, but is upregulated in injured tissue following myocardial infarction, vascular injury, and wound healing. AT2 receptor signaling is not dependent on G-protein coupling or receptor phosphorylation, although coupling to Gia2 and Gia3 alpha subunits occurs in some tissues. AT2 activation can stimulate tyrosine and serine/threonine phosphatases through activation of nitric oxide and cGMP, and appears to counteract the stimulatory effects of AT1 receptor and growth factor receptor signaling.


Catalog Number: (89145-536)
Supplier: Enzo Life Sciences
Description: Pentraxin 3 (PTX3), a member of the pentraxin family, is referred to as a long pentraxin and contains a unique PTX3 domain not found in C-reactive protein (CRP) or (Serum Amyloid P component) SAP. In contrast to CRP, PTX3 is produced from the major cell types involved in atherosclerotic lesions, namely vascular endothelial cells, vascular smooth muscle cells, macrophages, and nutrophils in response to inflammatory stimuli. Moreover, CRP is produced by the liver and represents a systemic response to local inflammation, whereas PTX3 is rapidly produced directly from damaged tissues and directly reflects the inflammatory state of the vasculature. PTX3 levels have been reported to be significantly elevated in acute myocardial infarction, and accordingly, statin treatment significantly decreases PTX3 levels. Due to the fact that PTX3 is able to reflect acute coronary syndrome (ACS) condition better than CRP, it is highly possible that PTX3 is a superior biomarker to predict future cardiovascular events.


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