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Catalog Number: (89146-694)
Supplier: Enzo Life Sciences
Description: Caspase-1 substrate


Supplier: Enzo Life Sciences
Description: Caspase-2 inhibitor

Supplier: Enzo Life Sciences
Description: Irreversible, cell permeable broad-spectrum caspase inhibitor.

Supplier: Enzo Life Sciences
Description: α-Crystallins composed of αA (~19 kDa) and αB (~19.2 kDa) subunits, are major water-soluble proteins accounting for almost 50% of total protein in the mammalian transparent eye lens and they are also found in a variety of other tissues. Alpha-crystallins are also referred to as small heat shock proteins, since they are induced by increased temperature in a variety of organisms. The α-crystallins have sequence homology as well as structural and functional similarities with the small Hsp’s such as Hsp25/27. Most α-crystallins have four common structural and functional features: (i) molecular weight between 12 and 43kDa; (ii) the formation of large oligomeric complexes composed of αA-crystallin, αB-crystallin and Hsp25/27; (iii) the moderately conserved α-crystallin domain in the central region of the protein; and (iv) molecular chaperone activity. The α-crystallin domain comprises approximately 90 residues, is bounded by variable N-terminal and C-terminal extensions and is involved in oligomer assembly. Oligomers can reach 800 kDa or more and are dynamic, exhibiting subunit exchanges and organizational plasticity, possibly leading to functional diversity. Phosphorylation of serine residues occurs during development and in response to stress, and usually decreases oligomer size. Chaperone activity requires, and is modulated by, oligomerization and is limited to binding unfolded intermediates to prevent irreversible aggregation. Although productive release and refolding of denatured proteins requires close cooperation with other chaperones. Other proposed functions include a role in membrane stabilization and modulation of intermediate filament organization during physiological stress and neurodegenerative disease. Alpha B Crystallin is phosphorylated on serine 45 by ERK1/2 and serine 59 by MAPKAPK-2. When mono-phosphoylated αB-crystallin is isolated it contains only αB-crystallin phosphorylated at serine 19.

Catalog Number: (89142-018)
Supplier: Enzo Life Sciences
Description: Produced in Sf9 cells using an N-terminal GST-tag.


Supplier: Enzo Life Sciences
Description: PKC inhibitor

Catalog Number: (89143-920)
Supplier: Enzo Life Sciences
Description: Serum copper transport protein


Catalog Number: (89143-928)
Supplier: Enzo Life Sciences
Description: Isolated from human rheumatoid synovial fibroblasts. Requires activation.


Supplier: Enzo Life Sciences
Description: ß-Nicotinamide adenine dinucleotide phosphate (NADP-Na<sub>2</sub>, oxidized form)

Catalog Number: (89151-428)
Supplier: Enzo Life Sciences
Description: DL-α-Tocopherol (Vitamin E) ≥97%, high purity


Catalog Number: (89156-458)
Supplier: Enzo Life Sciences
Description: A QuantiZymeTM Assay System


Catalog Number: (89156-434)
Supplier: Enzo Life Sciences
Description: Based on the dye cresyl violet and the caspase 3/7 DEVD peptide recognition sequence, this kit allows the detection of caspases 3 and 7 in living cells by fluorescence microscopy.


Catalog Number: (89156-416)
Supplier: Enzo Life Sciences
Description: A QUANTIZYME® Assay System Complete assay system designed to examine the specificity of inhibitors against a panel of ten matrix metalloproteinase enzymes. The assays are performed in a convenient 96-well microplate format using a chromogenic substrate1,2 detected at 412nm. Included are active MMP enzymes, assay buffer, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet.


Catalog Number: (89156-450)
Supplier: Enzo Life Sciences
Description: A QuantiZymeTM Assay System


Catalog Number: (89156-442)
Supplier: Enzo Life Sciences
Description: Based on the dye cresyl violet and the cathepsin K LeuArg peptide recognition sequence, this kit allows the detection of cathepsin K activity in living cells by fluorescence microscopy.


Catalog Number: (89156-456)
Supplier: Enzo Life Sciences
Description: A QuantiZyme™ Assay System


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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