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Supplier: Bachem Americas
Description: For atosiban see H-6722.

Catalog Number: (10781-870)
Supplier: Peprotech
Description: GDNF is a disulfide-linked, homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFRα (α1-α4) receptors. GDNF specifically promotes dopamine uptake and survival, and morphological differentiation of midbrain neurons. Using a Parkinson’s disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional murine GDNF ligand is a disulfide-linked homodimer consisting of two 15.1 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, including Cys-101, which is used for inter-chain disulfide bridging, and others that are involved in the intramolecular ring formation known as the cysteine knot configuration. The calculated molecular weight of Recombinant Murine GDNF is 30.2 kDa.


Catalog Number: (10109-170)
Supplier: Prosci
Description: MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.


Catalog Number: (103391-806)
Supplier: New England Biolabs (NEB)
Description: Chemically competent <i>E. coli</i> cells suitable for T7 protein expression with enhanced capacity to correctly fold proteins with multiple disulfide bonds in the cytoplasm.


Catalog Number: (CAAA14005-06)
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00064735

Catalog Number: (103391-808)
Supplier: New England Biolabs (NEB)
Description: Chemically competent <i>E. coli</i> cells suitable for T7 protein expression with enhanced capacity to correctly fold proteins with multiple disulfide bonds in the cytoplasm and with enhanced reduction of basal expression.


Supplier: Bachem Americas
Description: For atosiban see H-6722.

Catalog Number: (10072-596)
Supplier: Prosci
Description: Neurturin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, Artemin, and Persephin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Neurturin signals through a multicomponent receptor system, composed of RET and one of four GFR alpha (alpha1-alpha4) receptors. Neurturin promotes the development and survival of sympathetic and sensory neurons by signaling through a receptor system composed of RET and GFRalpha2. The functional form of human Neurturin is a disulfide-linked homodimer, of two 11.8 kDa polypeptide monomers (206 total amino acid residues). Each monomer contains seven conserved cysteine residues, one of which (Cys 69) is used for inter-chain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine knot configuration.


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00011227
Catalog Number: (89360-012)
Supplier: Genetex
Description: PRG2 is a cytotoxin and helminthotoxin. Also induces noncytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA. In pregnancy serum, the proform exists as a disulfide-linked 2:2 heterotetramer with PAPPA, as a disulfide-linked 2:2 heterotetramer with AGT, and as a complex (probably a 2:2:2 heterohexamer) with AGT and C3dg.


Catalog Number: (89270-462)
Supplier: Genetex
Description: Rabbit polyclonal antibody to ENOX1 (Middle)


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00049766 Decomposes in water. Soluble in carbon disulfide, chloroform, ethyl bromide
Catalog Number: (103008-468)
Supplier: Anaspec Inc
Description: This is a fluorescent (HiLyte™ Fluor 488)-labeled Endothelin 1 (ET-1) peptide, Abs/Em=503/528 nm.
Sequence:HiLyte™ Fluor 488-CSCSSLMDKECVYFCHLDIIW (Disulfide Bridge: 1-15 and 3-11)
MW:2848.4 Da
%Peak area by HPLC:≥95%
Storage condition: -20°C


Supplier: Thermo Scientific Chemicals
Description: For cleavage of disulfide bonds, as a polymerization crosslinking catalyst, as an organic intermediate, and in fuels
Supplier: Bachem Americas
Description: Induces elevation of cAMP and cGMP in rat aorta.

Catalog Number: (10339-142)
Supplier: Bioss
Description: This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. [provided by RefSeq].


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