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Tyrphostin B46 ≥98%

Supplier: Thermo Scientific Chemicals
Description: Inhibitor of EGF receptor kinase activity

Certificates

Image Unavailable-CAAAJ65227-MA

Tyrphostin C15

Catalog Number: (CAAAJ65227-MA)
Supplier: Thermo Scientific Chemicals
Description: A selective ErbB2 inhibitor
Product Image-89147-104

Tyrphostin AG 1295 ≥98%

Catalog Number: (89147-104)
Supplier: Enzo Life Sciences
Description: Selective inhibitor of tyrosine kinase in platelet-derived growth factor (PDGF) receptor.
Image Unavailable-TCT3074-200MG

Tyrphostin 1 ≥98.0% (by GC)

Supplier: TCI America
Description: Tyrphostin A1, Purity: >98.0%(GC), Cas number: 2826-26-8, Molecular Formula: C11H8N2O, Molecular Weight: 184.20, Synonyms: (4-Methoxybenzylidene)malononitrile, Tyrphostin 1, Appearance: Slightly pale yellow - Yellow solid crystal powder, Size: 1G

SDS

Image Unavailable-89157-742

Tyrphostin 1 ≥99%

Supplier: Enzo Life Sciences
Description: An inactive tyrphostin, which may be used as a negative control.

Product Image-89147-108

Tyrphostin AG 1478 ≥98% (by HPLC)

Catalog Number: (89147-108)
Supplier: Enzo Life Sciences
Description: EGFR inhibitor
Image Unavailable-89157-734

Tyrphostin AG-213 ≥99% (by TLC)

Catalog Number: (89157-734)
Supplier: Enzo Life Sciences
Description: A potent inhibitor of EGF receptor kinase activity (IC50‘s:EGFR = 2.4 µM, PDGFR = 3.5 µM, p210bcr-abl=5.9 µM, insulin receptor = 640 µM).
Image Unavailable-89157-914

Tyrphostin AG-126 ≥98% (by HPLC)

Supplier: Enzo Life Sciences
Description: AG-126 prevents lipopolysaccharide-induced lethal toxicity (septic shock) in mice. Administered at 1.5 mg/mouse, it reduced LPS-induced lethal toxicity from 95% to 10%. AG-126 greatly reduces LPS-induced tyrosine phosphorylation of p42MAPK in murine peritoneal macrophages at 50 µM. EGFR, Her-2/neu receptor or PDGF-R are not inhibited at 100 µM. Inhibits tyrosine kinase-dependent B cell receptor signaling.

Image Unavailable-89157-746

Tyrphostin A23 ≥99% (by TLC)

Catalog Number: (89157-746)
Supplier: Enzo Life Sciences
Description: A potent inhibitor of EGF receptor kinase activity (IC50=35 µM).
Image Unavailable-89157-822

Tyrphostin B7 ≥99% (by TLC)

Supplier: Enzo Life Sciences
Description: Member of the tyrphostin family of tyrosine kinase inhibitors. Selective inhibitor of the PDGF receptor kinase (IC50=20µM) vs. the EGF receptor kinase (IC50=820µM). Inhibits PDGF-induced mitogenesis in human bone marrow fibroblasts.

Product Image-89147-260

Tyrphostin AG 527 ≥98% (by HPLC)

Catalog Number: (89147-260)
Supplier: Enzo Life Sciences
Image Unavailable-89157-932

Tyrphostin AG 490 ≥98% (by TLC)

Supplier: Enzo Life Sciences
Description: AG-490 is a potent inhibitor of the JAK-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells, which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. At 5 µM, AG-490 almost completely blocked the growth of all pre-B ALL cells but had no significant effect on the growth of mitogen-stimulated normal B or T cells, B-cell lymphoma or T-cell leukemia cells. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. It blocks interleukin-7-induced JAK kinase activity in T-cells (JAK-1, JAK-3) and the consequent phosphorylation of PI-3 kinase. AG-490 is cell permeable and is a valuable tool for studying the cellular role of JAK kinases in signal transduction.

Image Unavailable-89157-794

Tyrphostin A9 ≥99% (by HPLC)

Supplier: Enzo Life Sciences
Description: Tyrphostin 9 is a selective inhibitor of the PDGF receptor tyrosine kinase (IC50=1.2 µM). It is also a potent (10 nM) uncoupler of oxidative phosphorylation.

Image Unavailable-89157-738

Tyrphostin AG 183 ≥99%

Catalog Number: (89157-738)
Supplier: Enzo Life Sciences
Description: A potent inhibitor of EGF receptor kinase activity (IC50=0.8 µM). Inhibition is mixed competitive with ATP and substrate.
Image Unavailable-CAAAJ61715-MC

Tyrphostin B42 ≥99%

Catalog Number: (CAAAJ61715-MC)
Supplier: Thermo Scientific Chemicals
Description: A protein kinase inhibitor

Certificates


Image Unavailable-89157-894

AG-879 ≥99%

Supplier: Enzo Life Sciences
Description: NGF receptor inhibitor

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