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Image Unavailable-75789-624

Human Recombinant LOX-1 (from Cells)

Catalog Number: (75789-624)
Supplier: Prosci
Description: Oxidized Low-Density Lipoprotein Receptor 1 (Ox-LDL Receptor 1) is a secreted, single-pass type II membrane protein which belongs to the C-type lectin superfamily. Ox-LDL Receptor 1 is expressed at high levels in endothelial cells and vascular-rich organs such as placenta, lung, liver, brain, aortic intima, bone marrow, spinal cord and substantia nigra. The expression of Ox-LDL Receptor 1 is induced by inflammatory cytokines such as TNF, IFNG and IL6 by pathological conditions, such as hyperlipidemia, hypertension and diabetes mellitus. Ox-LDL Receptor 1 mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (OxLDL) by vascular endothelial cells. Ox-LDL Receptor 1 association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. Ox-LDL Receptor 1 also binds to oxLDL, which acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. It also participates in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation.
Product Image-470163-070

Activity Series Kit

Catalog Number: (470163-070)
Supplier: Ward's Science
Description: Oxidation and Reduction of Metals

SDS


Image Unavailable-76101-546

Anti-LOX 1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76101-546)
Supplier: Bioss
Description: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).
Image Unavailable-CAAA12887-30

Cesium carbonate ≥99% (metals basis)

Supplier: Thermo Scientific Chemicals
Description: Catalyst in ethylene oxide polymerization, in coating spatter-free welding of steel in CO2, and in oxide cathodes

Certificates

Image Unavailable-TCI0141-025G

Methyl isonicotinate ≥99.0% (by titrimetric analysis)

Supplier: TCI America
Description: CAS Number: 2459-09-8
MDL Number: MFCD00006427
Molecular Formula: C7H7NO2
Molecular Weight: 137.14
Purity/Analysis Method: >99.0% (T)
Form: Clear Liquid
Boiling point (°C): 209
Flash Point (°C): 82
Freezing point (°C): 15
Specific Gravity (20/20): 1.16
Storage Temperature: 0-10°C

SDS Certificates

Product Image-470010-830

Ward's® Chemistry Acetylene-Chlorine Reaction Demonstration

Catalog Number: (470010-830)
Supplier: Avantor
Description: Study exothermic and oxidation-reduction reactions with ease.
Image Unavailable-CAAA33342-A4

D-(-)-Mannitol ≥99.0% ACS

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00064287 Beilstein Registry No.: 1721898 Soluble in water, alcohol, pyridine, aniline. Insoluble in ether

Certificates

Image Unavailable-89160-072

20-Hydroxyleukotriene B4 ≥99% (by HPLC)

Catalog Number: (89160-072)
Supplier: Enzo Life Sciences
Description: Primary LTB4 metabolite produced by ω oxidation in PMNL retaining some chemotactic activity. ω oxidation is blocked by 17-ODYA.
Image Unavailable-89138-192

Colorimetric and Fluorogenic Enzyme Substrates, Biotium

Supplier: Biotium
Description: Popular chromogenic and fluorogenic substrates for phosphatases, peroxidases, and other enzymes.

Image Unavailable-CAAA40013-36

Potassium bromate ≥99.8% ACS

Supplier: Thermo Scientific Chemicals
Description: As an analytical reagent, oxidizing agent

Certificates

Product Image-470310-420

American Chemical Society: Glow It Up Lab Activity

Catalog Number: (470310-420)
Supplier: Ward's Science
Description: How does a glow stick work?
Image Unavailable-CAAA12628-06

Ruthenium(III) bromide hydrate (≥25% Ru)

Supplier: Thermo Scientific Chemicals
Description: Uses: Oxidation Soluble in alcohol

Certificates

Image Unavailable-76084-808

Anti-eNOS Thr495 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76084-808)
Supplier: Bioss
Description: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
Image Unavailable-76471-664

Cutters, Standard, Excelta

Supplier: Excelta
Description: These high-quality cutters are designed for cutting small soft wire up to 250,000 times without resharpening.

Image Unavailable-CAAAJ60890-MF

Nω-Methyl-L-arginine monoacetate ≥99%

Catalog Number: (CAAAJ60890-MF)
Supplier: Thermo Scientific Chemicals
Description: Nitric oxide synthase inhibitor

Certificates


Image Unavailable-76101-548

Anti-LOX 1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76101-548)
Supplier: Bioss
Description: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).
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