You Searched For: Linoleic+anhydride

Catalog Number: (RK35012)

Supplier: Restek

Description: Contains: Chain, Compound (CAS#), % by Weight; C8:00 Methyl caprylate (111-11-5), 20%; C10:00 Methyl caprate (110-42-9), 20%; C12:00 Methyl laurate (111-82-0), 20%; C14:00 Methyl myristate (124-10-7), 20%; C16:00 Methyl palmitate (112-39-0), 20%

Catalog Number: (RK35022)

Supplier: Restek

Description: Contains: Chain, Compound (CAS#), % by Weight; C16:00 Methyl palmitate (112-39-0), 6%; C18:00 Methyl stearate (112-61-8), 3%; C18:01 Methyl oleate (112-62-9), 35%; C18:02 Methyl linoleate (112-63-0), 50%; C18:03 Methyl linolenate (301-00-8), 3%; C20:00 Methyl arachidate (1120-28-1), 3%

Catalog Number: (77439-954)

Supplier: Bioss

Description: Peroxisome proliferators are nongenotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family, termed Peroxisome Proliferator Activated Receptors (PPARs). Nuclear hormone receptors are ligand dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids. It has also been shown that PPARs can induce transcription of acyl coenzyme A oxidase and cytochrome P450 A6 (CYP450 A6) through interaction with specific response elements. PPAR alpha is activated by free fatty acids including linoleic, arachidonic, and oleic acids. Induction of peroxisomes by this mechanism leads to a reduction in blood triglyceride levels. PPAR alpha is expressed mainly in skeletal muscle, heart, liver, and kidney and is thought to regulate many genes involved in the beta-oxidation of fatty acids. Activation of rat liver PPAR alpha has been shown to suppress hepatocyte apoptosis. PPAR alpha, like several other nuclear hormone receptors, heterodimerizes with retinoic X receptor (RXR) alpha to form a transcriptionally competent complex.

Catalog Number: (76118-246)

Supplier: Bioss

Description: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.

Catalog Number: (89359-368)

Supplier: Genetex

Description: Peroxisome proliferators are non genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family, termed Peroxisome Proliferator Activated Receptors (PPARs). Nuclear hormone receptors are ligand dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids. It has also been shown that PPARs can induce transcription of acyl coenzyme A oxidase and cytochrome P450 A6 (CYP450 A6) through interaction with specific response elements. PPAR alpha is activated by free fatty acids including linoleic, arachidonic, and oleic acids. Induction of peroxisomes by this mechanism leads to a reduction in blood triglyceride levels. PPAR alpha is expressed mainly in skeletal muscle, heart, liver, and kidney and is thought to regulate many genes involved in the beta-oxidation of fatty acids. Activation of rat liver PPAR alpha has been shown to suppress hepatocyte apoptosis. PPAR alpha, like several other nuclear hormone receptors, heterodimerizes with retinoic X receptor (RXR) alpha to form a transcriptionally competent complex.

Catalog Number: (RK35035)

Supplier: Restek

Description: Contains: Chain, Compound (CAS#), % by Weight; C14:00 Methyl myristate (124-10-7), 0.1%; C16:00 Methyl palmitate (112-39-0), 26.3%; C16:01 Methyl palmitoleate (1120-25-8), 0.4%; C17:00 Methyl heptadecanoate (1731-92-6), 0.3%; C18:00 Methyl stearate (112-61-8), 33.7%; C18:01 Methyl oleate (112-62-9), 34.3%; C18:02 Methyl linoleate (112-63-0), 3.1%; C18:03 Methyl linolenate (301-00-8), 0.2%; C20:00 Methyl arachidate (1120-28-1), 1.3%; C20:01 Methyl eicosenoate (20839-34-3), 0.1%; C22:00 Methyl behenate (929-77-1), 0.2%

Catalog Number: (76118-244)

Supplier: Bioss

Description: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.

Catalog Number: (RK35011)

Supplier: Restek

Description: Contains: Chain, Compound (CAS#), % by Weight; C6:00 Methyl caproate (106-70-7), 20; C8:00 Methyl caprylate (111-11-5), 20; C10:00 Methyl caprate (110-42-9), 20; C12:00 Methyl laurate (111-82-0), 20; C14:00 Methyl myristate (124-10-7), 20

Catalog Number: (CA101106-274)

Supplier: Enzo Life Sciences

Description: HETEs are byproducts generated by the metabolism of arachidonic acid by lipoxygenases. 12(S)-HETE is the stereospecific hydroxy product from the reduction of 12(S)-hydroperoxy tetraenoic eicosatetraenoic acid [12(S)-HpETE], which itself is a 12-lipoxygenase metabolite of arachidonic acid. 12(S)-HETE is chemotactic and chemokinetic for polymorphonuclear leukocytes and vascular smooth muscle cells. It also acts as a second messenger in angiotensin-II induced aldosterone production. 15-hydroxyeicosatetraenoic acid [15(S)-HETE] is the major hydroxy derivative of arachidonic acid when acted upon by 15-lipoxygenase. It is also the primary monohydroxy acid synthesized by the lipoxygenase activity of Cyclooxygenase-1 upon linoleic acid. 15(S)-HETE acts as a paracrine regulator of smooth muscle and lung neutrophil recruitment, and elevated levels of 15(S)-HETE are associated with asthma, rhinitis, chronic paranasal sinusitis and rheumatoid arthritis.

Supplier: TCI America

Description: 3-Acetamidophthalic anhydride 98,0 GC, T

SDS

Supplier: Thermo Scientific Chemicals

Description: Isobutyric anhydride 97%

Certificates

Catalog Number: (CA8.00741.0100)

Supplier: MilliporeSigma

Description: Tetrachlorophthalic anhydride, CAS number:117-08-8, Synonyms:Tetrachloro-1,2-benzenedicarboxylic anhydride, Application:for synthesis

SDS Certificates

Supplier: TCI America

Description: 2-Methylbenzoic Anhydride, Purity: >98.0%(GC)(T), CAS Number: 607-86-3, Molecular Formula: C16H14O3, Molecular Weight: 254.29, Size: 5G

Supplier: Thermo Scientific Chemicals

Description: Trichloroacetic anhydride 95%

Certificates

Supplier: Thermo Scientific Chemicals

Description: MDL: MFCD00000432

Certificates

Supplier: Thermo Scientific Chemicals

Description: 3-Fluorophthalic anhydride 98%

Certificates