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Catalog Number: (10432-534)
Supplier: Bioss
Description: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Also able to demethylated 'Lys-372' of p53/TP53 in vitro.


Catalog Number: (700001-140)
Supplier: Spectrum Chemicals
Description: Cupric Chloride, Dihydrate, Crystal, Reagent, ACS is also known as copper chloride. It is a chemical compound with a blue green color. Copper (II) chloride is used as a synthetic catalyst, a pyrotechnic coloring agent and in humidity indicator cards. The Reagent grade denotes that this chemical is the highest quality commercially available and that the American Chemical Society has not officially set any specifications for this material. Spectrum Chemical manufactured Reagent grade products meet the toughest regulatory standards for quality and purity.

Catalog Number: (76109-008)
Supplier: Bioss
Description: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).


Catalog Number: (10432-542)
Supplier: Bioss
Description: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Also able to demethylated 'Lys-372' of p53/TP53 in vitro.


Supplier: MilliporeSigma
Description: Cobalt(ii) chloride hexahydrate 100g, for analysis emsure*acs, reag. ph eur, plastic bottle, 100 g, 7791-13-1, cocl2 * 6 h2o
Supplier: MilliporeSigma
Description: Tin(II) chloride dihydrate, Grade:ACS,ISO,Reag. Ph Eur, CAS number:10025-69-1, Synonyms:Tin dichloride, dihydrate, Stannous chloride, Application:for analysis EMSUR
Supplier: MilliporeSigma
Description: Manganese(II) chloride tetrahydrate, Grade:ACS, CAS number:13446-34-9, synonyms:Manganese dichloride, Application:for analysis EMSURE
Catalog Number: (76099-978)
Supplier: Bioss
Description: Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II).


Catalog Number: (CA1.04417.0100)
Supplier: MilliporeSigma
Description: Mercury(II) chloride extra pure fine cryst, CAS number:7487-94-7, synonyms:Mercury dichloride

Supplier: MilliporeSigma
Description: Nickel(II) chloride hexahydrate, Grade:ACS, CAS number:7791-20-0, Synonyms:Nickel dichloride, Application:for analysis EMSURE
Supplier: Ward's Science
Description: CAS Number: 10025-69-1
Formula Weight: 225.63
Formula: SnCl2·2H2O
Density (g/mL): 2.71
Freezing Point (°C): 38
Solubility: Water, Alkalies, Tartaric Acid and Alcohol
Synonyms: Stannous Chloride, Dihydrate
Shelf Life (months): 12
Storage: White

SDS

Supplier: Thermo Scientific Chemicals
Description: Cobalt(II) chloride hexahydrate 98%
Catalog Number: (76099-980)
Supplier: Bioss
Description: Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II).


Supplier: Thermo Scientific Chemicals
Description: Mercury(II) chloride 98+%
Supplier: Thermo Scientific Chemicals
Description: Tin(II) chloride dihydrate 98.0-103.0% ACS
Supplier: MilliporeSigma
Description: Mercury(II) chloride, Grade:Reag. Ph Eur,ACS, CAS number:7487-94-7, synonyms:Mercury dichloride, Application:for analysis EMSURE
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