You Searched For: H-D-Lys(Z)-OH


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Supplier: Bachem Americas
Description: HCKFWW, potent inhibitor of the HIV-encoded integrase (IN), the enzyme responsible for the integration of HIV DNA into the human genome. HCKFWW inhibits IN-mediated 3'processing and integration with an IC₅₀ of 2 µM. The peptide is also active on IN proteins from other retroviruses such as HIV-2, feline immunodeficiency virus and Moloney murine leukemia virus. It was also found to inhibit the disintegration reaction, suggesting that this hexapeptide acts at or near the catalytic site of IN.

Supplier: TCI America
Description: CAS Number: 10009-20-8
MDL Number: MFCD00037223
Molecular Formula: C8H13F3N2O3
Molecular Weight: 242.20
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Color: White
Melting point (°C): 254
Specific rotation [a]20/D: 19 deg (C=1, 1mol/L HCl)
Storage Temperature: 0-10°C
Supplier: TCI America
Description: CAS Number: 92122-45-7
MDL Number: MFCD00065660
Molecular Formula: C26H32N2O6
Molecular Weight: 468.55
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 130
Specific rotation [a]20/D: 2.2 deg (C=1, MeOH)
Storage Temperature: 0-10°C

SDS

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: L(+)-Lysine monohydrochloride 98.5-101.5% (dried basis), GenAR® USP, Multi-Compendial, Macron Fine Chemicals™
Catalog Number: (B-4295.0005BA)
Supplier: Bachem Americas
Description: These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.


Supplier: Thermo Scientific Chemicals
Description: L(+)-Lysine dihydrochloride 99%
Catalog Number: (103003-356)
Supplier: Anaspec Inc
Description: ACTH (1–17), and aMSH (a-Melanotropin), both derived from POMC (proopiomelanocortin) are involved in melanogenesis. However, ACTH (1-17) has been found to be more potent in malanogenesis in human malanocytes. Both ACTH (1-17) and aMSH also increase dendricity, and proliferation in follicular melanocytes.
Sequence: SYSMEHFRWGKPVGKKR
MW: 2093.4 Da
% Peak Area by HPLC: ≥ 95%
Storage condition: -20°C


Supplier: Thermo Scientific Chemicals
Description: Nε-carbobenzoxy-L-lysine 98%
Supplier: Bachem Americas
Description: Reaction of the dipeptide KY with diethylenetriaminepentaacetic (DTPA) cyclic anhydride yielded monovalent and bivalent haptens. In vitro, the antibody conjugate (which was prepared by coupling F(ab’)2 or Fab’ fragments of an antibody specific for the human high molecular weight melanoma associated antigen to Fab’ fragments of an antibody specific for In-DTPA complexes) mediated binding of the ¹¹¹In-labeled haptens to melanoma cells. In vivo, it allowed specific localization of the haptens in A375 tumors. The bivalent hapten exhibited much higher efficiency at targeting ¹¹¹In onto cells, both in vitro and in vivo.

Supplier: Thermo Scientific Chemicals
Description: Powder
Catalog Number: (M-2115.0001BA)
Supplier: Bachem Americas
Description: This internally quenched fluorogenic peptide substrate contains anthranilic acid as fluorescent donor and m-nitro-tyrosine as acceptor (quencher). The sequence Abz-RVKRGLAY(NO₂)E is based on the sequence of hemagglutinin. The FRET substrate is efficiently cleaved by furin, a subtilisin-like eukaryotic serine endoprotease with Km = 3.8 µM and kcat = 29.3 s⁻¹ (kcat/Km = 7'710'000 M⁻¹s⁻¹). Its kcat/Km value is over 2000-fold higher than that of the commonly used substrate Boc-Arg-Val-Arg-Arg-AMC (I-1645). FRET Substrate for the basic residue-specific yeast aspartyl protease yapsin 1.


Supplier: Bachem Americas
Description: See also E-2410, Suc-Pro-OH, the product familiy 'Antihypertensive Peptides' and the subfamily 'Bradykinin-Potentiating Peptides (BPP)'.

Catalog Number: (CAPI88429)
Supplier: Thermo Scientific
Description: Thermo Scientific Heavy and Light Amino Acids are used to specifically analyze protein expression by mass spectrometry using stable isotope labeling with amino acids in cell culture (SILAC) quantification kits.

Catalog Number: (CAPI89987)
Supplier: Thermo Scientific
Description: Thermo Scientific Heavy and Light Amino Acids are used to specifically analyze protein expression by mass spectrometry using stable isotope labeling with amino acids in cell culture (SILAC) quantification kits. Store at 2 - 8˚C.

Supplier: Bachem Americas
Description: The bioactive tetrapeptide goralatide which corresponds to the N-terminus of Thymosin β₄, is a physiological regulator of hematopoiesis and inhibits the entry into the S-phase of murine and human hematopoietic stem cells. Ac-SDKP has been shown to reduce the damage to specific compartments in the bone marrow resulting from treatment with chemotherapeutic agents, ionizing radiations, hyperthermy, or phototherapy. It protects from doxorubicin-induced toxicity. Ac-SDKP is a physiological substrate of angiotensin I- converting enzyme (ACE).

Catalog Number: (102996-478)
Supplier: Anaspec Inc
Description: Aß (25-35) is the main factor responsible for Aß neurotoxic effects.


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