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Supplier: Thermo Scientific Chemicals
Supplier: Peprotech
Description: Human IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor, to activate NF-κB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Recombinant Human IL-33 is a 17.9 kDa protein containing 159 amino acid residues.

Catalog Number: (CAAA43345-02)
Supplier: Thermo Scientific Chemicals
Description: Applications: laser dye
Soluble in methanol, toluene

Supplier: Bachem Americas
Description: Sequence: (Fmoc-Cys-OH)₂

Supplier: Adipogen
Description: Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.

Supplier: Thermo Scientific Chemicals
Description: Powder, packaged under argon
Supplier: Peprotech
Description: IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor, to activate NF-κB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Recombinant Murine IL-33 is a 17.5 kDa protein containing 158 amino acid residues.

Supplier: TCI America
Description: CAS Number: 620-45-1
MDL Number: MFCD00150015
Molecular Formula: C12H7Cl2NO2
Molecular Weight: 290.07
Purity/Analysis Method: >95.0% (T)
Form: Crystal
Catalog Number: (103003-038)
Supplier: Anaspec Inc
Description: Purified metalloendopeptidase cleaves the Gly33-Leu34 bond of Alzheimer Aß (1-40) peptide producing soluble 1-33 and 34-40 fragments of Aß (1-40) without any neurotoxic effects.
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIG
Molecular Weight: 3674 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C


Supplier: TCI America
Description: CAS Number: 52789-62-5
MDL Number: MFCD00068275
Molecular Formula: C10H9NO7S2
Molecular Weight: 341.28
Purity/Analysis Method: >85.0% (HPLC,T)
Form: Crystal
Supplier: Adipogen
Description: Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL-33 binds to and signals through ST2 (IL-1R1) and its stimulation recruits MYD88, IRAK, IRAK4 and TRAF6, followed by phosphorylation of ERK1 (MAPK3) / ERK2 (MAPK1), p38 (MAPK14) and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases and sepsis. IL-33 facilitates Treg expansion in vitro and in vivo. Recently, IL-33 has been involved in adipocyte differentiation. The biological activity of IL-33 at its receptor ST2 is rapidly terminated in the extracellular environment by its oxidation (formation of two disulfide bridges), resulting in an extensive conformational change that disrupts the ST2 binding site. Mutations at amino acids C208S/C232S protect IL-33 from oxidation and increase its activity.

Supplier: TCI America
Description: [NH2Me2][(RuCl((R)-dm-segphos*))2(u-Cl)3], CAS Number: 935449-46-0, MF: C94H96Cl5NO8P4Ru2, MW: 1871.09, Synonym: Dimethylammonium Dichlorotri(u-chloro)bis[(R)-(+)-5,5-bis[di(3,5-xylyl)phosphino]-4,4-bi-1,3-benzodioxole]diruthenate(II), Size: 200MG

SDS

Supplier: Thermo Scientific Chemicals
Description: Magnesium phosphate pentahydrate (33% P₂O₅)
Supplier: Bachem Americas
Description: CART (Cocaine- and Amphetamine-Regulated Transcript) is a recently discovered peptide, which was initially identified as mRNA produced primarily in the rat hypothalamus after administration of psychomotor stimulants. It is a satiety factor and closely associated with the actions of two important regulators of food intake, leptin and neuropeptide Y. When systemic leptin or receptors for leptin are inhibited, expression of CART mRNA is suppressed. CART (55-102) has been isolated from the hypothalamus of ovine suggesting in vivo processing at the Lys⁵³-Arg⁵⁴ region. When injected intracerebroventricularly into rats, recombinant CART peptides inhibited both normal and starvation-induced feeding, and completely blocked the feeding response induced by neuropeptide Y. Thus far, CART (55-102) appears to be the most potent fragment with a conserved secondary structure consisting of three disulfide bridges. Disruption of this secondary structure by reduction leads to a loss of the appetite induction.

Catalog Number: (103007-408)
Supplier: Anaspec Inc
Description: This is amino acids 25 to 33 fragment of human melanoma antigen gp100. This H-2Db restricted epitope is recognized by T cells. The gp100-specific, H-2Db-restricted, CD8+ T cells are capable of recognizing B16 melanoma but not normal melanocytes. This peptide was used as an immunogen in multiple cancer immunotherapy studies.
Sequence: KVPRNQDWL
MW: 1155.3 Da
% Peak area by HPLC: 95
Storage condition: -20°C


Supplier: TCI America
Description: [NH2Me2][(RuCl((S)-dm-segphos*))2(u-Cl)3], CAS Number: 944451-14-3, MF: C94H96Cl5NO8P4Ru2, MW: 1871.09, Synonym: Dimethylammonium Dichlorotri(u-chloro)bis[(S)-(-)-5,5-bis[di(3,5-xylyl)phosphino]-4,4-bi-1,3-benzodioxole]diruthenate, Size: 200MG

SDS

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