Monarch® Nucleic Acid Purification

Monarch® Nucleic Acid Purification Kits for DNA and RNA are the perfect complement to many molecular biology workflows, including cloning, PCR, enzyme digests,  qPCR, RNA synthesis & analysis, and library preparation for NGS. Recover pure, intact DNA and RNA in minutes with our fast, user-friendly protocols and optimized buffer systems, and focus your time on the experiments that will drive your research forward. 

Monarch DNA and RNA Cleanup columns are designed without a retaining ring, eliminating buffer carryover and allowing for low volume elution.  The Monarch Total RNA Miniprep Kit is optimized for use with a wide variety of sample types, so that one convenient kit can serve your RNA extraction needs. 

Monarch kits are all designed with sustainability in mind; whenever possible, kits and components are made with
significantly less plastic and are packaged with responsibly-sourced, recyclable packaging. Further, plastic recovered
during the manufacture of Monarch columns is used to manufacture other plastic-based NEB products.

Product selection

Monarch Plasmid Miniprep Kit

Rapidly and reliably purify high quality plasmids from bacteria. Benefit from colored buffers, low elution volumes, and enjoy a sustainable design.

Monarch DNA Gel Extraction Kit

Extract and purify high quality DNA from agarose gels with excellent yields. Use elution volumes as low as 6 µl for highly concentrated DNA.

Monarch PCR & DNA Cleanup Kit (5 µg)

Rapidly purify high-quality DNA fragments from PCR and other enzymatic reactions. This kit can also be used for purification of oligonucleotides.

Monarch Total RNA Miniprep Kit

Purify total RNA > 20 nts from cells, tissues, blood and other samples using one convenient kit. Dnase I, Prot K & stabilization reagent included.

Monarch RNA Cleanup Kits

Quickly clean up & concentrate RNA after IVT, enzymatic treatment, and extraction. Available in 3 different binding capacities: 10, 50, and 500 μg.

Monarch HMW DNA Extraction Kits

Extract HMW DNA rapidly < 90 min using a novel glass bead-based method. Achieve DNA in Mb range for long read sequencing.

Monarch Genomic DNA Extraction Kits

Purify genomic DNA using silica-based method. Generate high DNA purity & yields from even challenging tissues for downstream qPCR, NGS, sequencing.