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Catalog Number: (CAPIPA5-18387)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with mouse and rat based on sequence homology. This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Catalog Number: (CAPIPA5-18388)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.

Catalog Number: (CAPIPA5-18396)

Supplier: Thermo Scientific

Description: Current literature indicates that mammaglobin, as measured by the ELISA, holds significant promise for breast cancer screening with the realistic potential to impact management of this disease.

Catalog Number: (CAPIPA5-18386)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with canine, mouse and rat based on sequence homology. Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

Catalog Number: (CAPIPA5-18403)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with canine, mouse and rat based on sequence homology. This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, tstart codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Catalog Number: (CAPI77164)

Supplier: Thermo Scientific

Description: Imject™ maleimide conjugation buffer (30 mL) is sufficient for dissolving up to 60 mg of sulfhydryl-peptide for maleimide conjugation with carrier proteins.

SDS Certificates

Catalog Number: (CAPI77171)

Supplier: Thermo Scientific

Description: Imject™ Bovine Serum Albumin (BSA) in MES Buffer is a carrier protein that enable simple preparation of effective immunogens with amine- or carboxyl-peptide antigens.

SDS Certificates

Catalog Number: (CAPI21123)

Supplier: Thermo Scientific

Description: Pierce™ HRP conjugated avidin is used in biotin-based detection methods, including Western blotting or ELISA detection with appropriate enzyme substrates.

SDS

Catalog Number: (CAPIPA5-13515)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with rabbit based on sequence homology. FUT1 is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway.

Catalog Number: (CAPIPA5-13518)

Supplier: Thermo Scientific

Description: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Catalog Number: (CAPIPA5-13476)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with non-human primate based on sequence homology. Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.

Catalog Number: (CAPIPA526743)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with mouse and rat based on sequence homology. CACNA2D3 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.

Catalog Number: (CAPIPA5-13663)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with rat based on sequence homology. KRT10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in its gene are associated with epidermolytic hyperkeratosis.

Catalog Number: (CAPI36000)

Supplier: Thermo Scientific

Description: The Pierce™ Peroxidase IHC Detection Kit bundles the Pierce™ Metal Enhanced DAB Substrate Kit with all necessary components to stain, counterstain and preserve experimental results with frozen or paraffin tissue sections.

SDS

Catalog Number: (CAPIPA5-18556)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with canine, human and rat based on sequence homology. The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

Catalog Number: (CAPIPA5-18547)

Supplier: Thermo Scientific

Description: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine , a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.