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Anti-CD57 HNK-1 Mouse Monoclonal Antibody [clone: NK-1]

Catalog Number: (CA76634-382)
Supplier: Diagnostic Biosystems
Description: This antibody is specific to a 110 kDa human CD57 myeloid associated glycoprotein. It stains mononuclear cells with natural killer activity, neuroendocrine cells and their tumors.
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Anti-E-Cadherin Mouse Monoclonal Antibody [clone: SPM471]

Supplier: Diagnostic Biosystems
Description: E-cadherin (uvomorulin, cell-CAM120/80) is a calcium dependent cell adhesion molecule expressed predominately in epithelial tissues. It plays an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Numerous studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.

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Anti-MART-1/Melan-A Mouse Monoclonal Antibody [clone: A103]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to a protein of 20 kDa known as MART-1 (melanoma antigen recognized by T cells-1) or Melan-A. This antibody does not cross-react with MAGE-1or tyrosinase. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. This antibody stains melanomas and other tumors showing melanocytic differentiation.

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Anti-Cytokeratin (45 46 56.4 kD) Mouse Monoclonal Antibody [clone: MNF116]

Supplier: Diagnostic Biosystems
Description: This antibody recognizes cytokeratin polypeptides ranging from 40 to 58 kDa, corresponding to cytokeratins 5, 6, 8,17 and 19. It shows a broad pattern of reactivity with human epithelial tissues from simple glandular epithelia to stratified squamous epithelia, like epidermis, mammary gland ducts and tracheal epithelium.

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Anti-CA 15-3 Mouse Monoclonal Antibody [clone: DBMM1]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to epithelial membrane antigen (EMA), CA 15-3, or polymorphic epithelial mucin. This antibody stains an underglycosylated MUC1 often present on carcinoma cells.

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Anti-Amyloid precursor protein (APP) Rabbit Polyclonal Antibody

Catalog Number: (CA76634-684)
Supplier: Diagnostic Biosystems
Description: This antibody reacts with a 95 to 100 kDa protein. This antibody recognizes amyloid precursor proteins APP695, APP751 and APP770. Amyloid precursor protein and APP-like proteins are transmembrane glycoproteins with a similar modular domain structure.
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Anti-Vascular Endothelial Growth Factor (VEGF) Mouse Monoclonal Antibody [clone: VG1]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to a cluster of proteins between 19-22 kDa (reduced). VEGF is a homodimeric disulfide-linked glycoprotein involved in angiogenesis, which promotes tumor progression and metastasis. It exhibits potent mitogenic and permeability-inducing properties specific for the vascular endothelium.

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Anti-EMA Mouse Monoclonal Antibody [clone: E29]

Supplier: Diagnostic Biosystems
Description: This antibody reacts with an antigen of 265 to 400 kDa belonging to a heterogeneous group of heavily glycosylated proteins called human milk fat globule proteins. It stains both normal and neoplastic cells. Among normal epithelia, it reacts strongly with mammary epithelium and glandular epithelia but shows a patchy staining with squamous epithelium.

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Anti-Melanoma Mouse Monoclonal Antibody [clone: PNL2]

Supplier: Diagnostic Biosystems
Description: This antibody reacts with a neuraminidase sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. It reacts with junctional and blue nevus cells. Non-melanocytic cells are negative.

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Anti-HLA-DR β chain of DP DQ and DR Mouse Monoclonal Antibody [clone: CR3/43]

Catalog Number: (CA76633-218)
Supplier: Diagnostic Biosystems
Description: This antibody reacts with the β chain of all products of the gene sub regions DP, DQ, and DR. It stains B cells, interdigitating reticulum cells, Langerhans cells and many macrophages. This antibody does not react with normal T cell and polymorphs, but stains activated T cells.
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Anti-CD74 B cell Mouse Monoclonal Antibody [clone: LN2]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to CD74. This antibody can be used for the identification of B cell lymphomas and leukemias. It also stains activated neoplastic cells in T cell lymphomas and Sternberg-Reed cells.

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Anti-XRCC1 Mouse Monoclonal Antibody [clone: 33-2-5]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to an 85 kDa protein known as XRCC1. X-ray repair cross complementing 1 (XRCC1) protein plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels.

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Anti-CD68 Macrophage Mouse Monoclonal Antibody [clone: PG-M1]

Supplier: Diagnostic Biosystems
Description: This antibody reacts with a glycoprotein of 110 kDa, expressed as intracytoplasmic molecule. It stains macrophages in a wide variety of tissues. Myeloid precursor cells and peripheral granulocytes are negative. The PG-M1 differs from EMB11 (CD68) because of its non-reactivity with granulocytes and their precursor cells.

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Anti-Myeloperoxidase Mouse Monoclonal Antibody [clone: 59A5]

Catalog Number: (CA76634-528)
Supplier: Diagnostic Biosystems
Description: Myeloperoxidase metabolizes most of the hydrogen peroxide generated by activated phagocytes. This antibody stains strongly with the cytoplasm of myeloid cells. The antibody detects myeloperoxidase found in myeloid cells of acute myeloid leukemia. The myeloperoxidase gene has been localized to chromosome 17.
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Anti-Microphthalmia Mouse Monoclonal Antibody [clone: D5]

Catalog Number: (CA76634-438)
Supplier: Diagnostic Biosystems
Description: This antibody reacts with a 52 to 56 kDa protein known as microphthalmia (Mi). This antibody reacts with both melanocytic and non-melanocytic isoforms of Mi. Mi is a basic helix-loop-helix-leucine zipper (b-HLH-ZIP) transcription factor implicated in pigmentation, mast cells and bone development. There are two known isoforms of Mi differing by 66 amino acids at the amino terminus.
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Anti-HER2/neu (c-erb-2) Rabbit Monoclonal Antibody [clone: SP3]

Supplier: Diagnostic Biosystems
Description: This antibody recognizes a c-erbB-2 protein, which is a receptor tyrosine kinase of the c-erbB family. It is closely related in structure to the epidermal growth factor receptor. c-erbB-2 oncoprotein is detectable in a subset of breast and other adenocarcinomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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