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Anti-Vascular Endothelial Growth Factor (VEGF) Mouse Monoclonal Antibody [clone: VG1]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to a cluster of proteins between 19-22 kDa (reduced). VEGF is a homodimeric disulfide-linked glycoprotein involved in angiogenesis, which promotes tumor progression and metastasis. It exhibits potent mitogenic and permeability-inducing properties specific for the vascular endothelium.

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Anti-Cytokeratin (45 46 56.4 kD) Mouse Monoclonal Antibody [clone: MNF116]

Supplier: Diagnostic Biosystems
Description: This antibody recognizes cytokeratin polypeptides ranging from 40 to 58 kDa, corresponding to cytokeratins 5, 6, 8,17 and 19. It shows a broad pattern of reactivity with human epithelial tissues from simple glandular epithelia to stratified squamous epithelia, like epidermis, mammary gland ducts and tracheal epithelium.

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Anti-E-Cadherin Mouse Monoclonal Antibody [clone: SPM471]

Supplier: Diagnostic Biosystems
Description: E-cadherin (uvomorulin, cell-CAM120/80) is a calcium dependent cell adhesion molecule expressed predominately in epithelial tissues. It plays an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Numerous studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.

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Anti-CA 15-3 Mouse Monoclonal Antibody [clone: DBMM1]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to epithelial membrane antigen (EMA), CA 15-3, or polymorphic epithelial mucin. This antibody stains an underglycosylated MUC1 often present on carcinoma cells.

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Anti-Cytokeratin 17 Mouse Monoclonal Antibody [clone: E3]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to 46 kDa cytokeratin protein designated cytokeratin 17. It reacts with basal cells in complex epithelia and reacts strongly with squamous cell carcinomas.

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Anti-Epithelial Antigen Mouse Monoclonal Antibody [clone: VU-1D9]

Supplier: Diagnostic Biosystems
Description: This antibody reacts with two glycoproteins of 34 and 49 kDa present on the epithelial cells. It stains with simple epithelia and basal layers of stratified non-keratinized squamous epithelium.

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Anti-Glial Fibrillary Acidic Protein (GFAP) Mouse Monoclonal Antibody [clone: GA5]

Supplier: Diagnostic Biosystems
Description: This antibody reacts with the 52 kDa intermediate filament protein GFAP in brain and spinal cord. It labels some astrocytes and some CNS ependymal cells but not oligodendrocytes or neurons. This antibody does not react with other intermediate filament proteins.

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Anti-Amyloid precursor protein (APP) Rabbit Polyclonal Antibody

Catalog Number: (CA76634-684)
Supplier: Diagnostic Biosystems
Description: This antibody reacts with a 95 to 100 kDa protein. This antibody recognizes amyloid precursor proteins APP695, APP751 and APP770. Amyloid precursor protein and APP-like proteins are transmembrane glycoproteins with a similar modular domain structure.
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Anti-CD15 Mouse Monoclonal Antibody [clone: MMA]

Catalog Number: (CA76634-378)
Supplier: Diagnostic Biosystems
Description: This antibody reacts with a 220 kDa protein. CD15 plays a role in mediating phagocytosis, bactericidal activity and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. CD15 is also expressed in Reed-Sternberg cells and some epithelial cells. CD15 is very useful in the identification of Hodgkin disease.
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Anti-SALL4 Mouse Monoclonal Antibody [clone: 6E3]

Catalog Number: (CA76634-588)
Supplier: Diagnostic Biosystems
Description: Sal-like protein 4 (SALL4) is a zinc-finger transcription factor that serves as a master regulator of embryonic pluripotency and is involved in processes associated with stem cell activities. SALL4 expression in germ cells makes it a useful marker for germ cell tumors such as seminoma, embryonal carcinoma, yolk sac tumors and teratomas. SALL4 expression is also seen in the spermatogonia of normal testis.
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Anti-CD57 HNK-1 Mouse Monoclonal Antibody [clone: NK-1]

Catalog Number: (CA76634-382)
Supplier: Diagnostic Biosystems
Description: This antibody is specific to a 110 kDa human CD57 myeloid associated glycoprotein. It stains mononuclear cells with natural killer activity, neuroendocrine cells and their tumors.
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Anti-EMA Mouse Monoclonal Antibody [clone: E29]

Supplier: Diagnostic Biosystems
Description: This antibody reacts with an antigen of 265 to 400 kDa belonging to a heterogeneous group of heavily glycosylated proteins called human milk fat globule proteins. It stains both normal and neoplastic cells. Among normal epithelia, it reacts strongly with mammary epithelium and glandular epithelia but shows a patchy staining with squamous epithelium.

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Anti-Melanoma Mouse Monoclonal Antibody [clone: PNL2]

Supplier: Diagnostic Biosystems
Description: This antibody reacts with a neuraminidase sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. It reacts with junctional and blue nevus cells. Non-melanocytic cells are negative.

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Anti-MART-1/Melan-A Mouse Monoclonal Antibody [clone: A103]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to a protein of 20 kDa known as MART-1 (melanoma antigen recognized by T cells-1) or Melan-A. This antibody does not cross-react with MAGE-1or tyrosinase. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. This antibody stains melanomas and other tumors showing melanocytic differentiation.

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Anti-XRCC1 Mouse Monoclonal Antibody [clone: 33-2-5]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to an 85 kDa protein known as XRCC1. X-ray repair cross complementing 1 (XRCC1) protein plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels.

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Anti-Myeloperoxidase Mouse Monoclonal Antibody [clone: 59A5]

Catalog Number: (CA76634-528)
Supplier: Diagnostic Biosystems
Description: Myeloperoxidase metabolizes most of the hydrogen peroxide generated by activated phagocytes. This antibody stains strongly with the cytoplasm of myeloid cells. The antibody detects myeloperoxidase found in myeloid cells of acute myeloid leukemia. The myeloperoxidase gene has been localized to chromosome 17.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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