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Anti-Epithelial Antigen Mouse Monoclonal Antibody [clone: VU-1D9]

Supplier: Diagnostic Biosystems
Description: This antibody reacts with two glycoproteins of 34 and 49 kDa present on the epithelial cells. It stains with simple epithelia and basal layers of stratified non-keratinized squamous epithelium.

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Anti-ERCC1 Mouse Monoclonal Antibody [clone: 8F1]

Catalog Number: (CA76634-410)
Supplier: Diagnostic Biosystems
Description: This antibody reacts with a 33 to 36 kDa protein known as ERCC1 (excision repair cross complementing) polypeptide. ERCC1 is required for nucleotide excision repair of damaged DNA and is homologous to RAD10. In mammalian cells, XPG cleaves 3’ of the DNA lesion while ERCC1-XPF complex makes the 5’ incision.
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Anti-Mucin 5AC Mouse Monoclonal Antibody [clone: 45M1]

Catalog Number: (CA76634-428)
Supplier: Diagnostic Biosystems
Description: This antibody reacts with a 1000 kDa protein and recognizes the peptide core of gastric mucin M1. Mucins are high molecular weight glycoproteins with 80% carbohydrates and 20% core protein. Gastric mucin M1 antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or changes in the glycosylation pattern of mucin, which expose the hidden M1 antigen.
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Anti-PAX-8 Mouse Monoclonal Antibody [clone: 4H7B3]

Catalog Number: (CA76634-456)
Supplier: Diagnostic Biosystems
Description: PAX 8 is expressed in a high percentage of renal cell carcinomas and ovarian cancers. This mouse monoclonal PAX 8 antibody [4H7B3] has been designed to target restricted epitopes, and exhibits higher specificity and provides sharper staining than the PAX 8 rabbit polyclonal antibody. Unlike the polyclonal PAX 8, this mouse monoclonal antibody does not stain B-cells, and does not recognize epitopes of pancreatic origin and neuroendocrine cells in stomach and colon; thus providing superior specificity. The expression of the mouse monoclonal PAX 8 targets antigens found in normal kidney, thyroid and cervix, but not normal ovary. PAX 8 stains nuclei exclusively and performs well in formalin-fixed paraffin-embedded tissues.
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Anti-Melanoma Mouse Monoclonal Antibody [clone: PNL2]

Supplier: Diagnostic Biosystems
Description: This antibody reacts with a neuraminidase sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. It reacts with junctional and blue nevus cells. Non-melanocytic cells are negative.

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Anti-CD68 Macrophage Mouse Monoclonal Antibody [clone: PG-M1]

Supplier: Diagnostic Biosystems
Description: This antibody reacts with a glycoprotein of 110 kDa, expressed as intracytoplasmic molecule. It stains macrophages in a wide variety of tissues. Myeloid precursor cells and peripheral granulocytes are negative. The PG-M1 differs from EMB11 (CD68) because of its non-reactivity with granulocytes and their precursor cells.

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Anti-Ki-67 Rabbit Polyclonal Antibody

Supplier: Diagnostic Biosystems
Description: This antibody reacts with a nuclear antigen present in proliferating human cells. It can be used to evaluate the Ki-67 labeling index in various tumors.

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Anti-Inhibin Mouse Monoclonal Antibody [clone: R1]

Supplier: Diagnostic Biosystems
Description: Inhibin is a dimeric glycoprotein hormone from the TGF-β family made of β and α subunits. This antibody recognizes the 32kDa α subunit of human inhibin. Inhibin α is expressed in a wide variety of human tissues, such as brain, prostate, adrenal, granulose cells of ovary, sertoli cells of testis and in fetoplacental unit.

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Anti-XRCC1 Mouse Monoclonal Antibody [clone: 33-2-5]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to an 85 kDa protein known as XRCC1. X-ray repair cross complementing 1 (XRCC1) protein plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels.

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Anti-Cytokeratin 17 Mouse Monoclonal Antibody [clone: E3]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to 46 kDa cytokeratin protein designated cytokeratin 17. It reacts with basal cells in complex epithelia and reacts strongly with squamous cell carcinomas.

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Anti-CD3 Mouse Monoclonal Antibody [clone: F7.2.38]

Supplier: Diagnostic Biosystems
Description: The clone F7.2.38 is specific for the non-glycosylated epsilon chain of the human CD3 molecule. Clone F7.2.38 recognizes T cells in the thymus, bone marrow, peripheral lymphoid tissue and blood and is a pan T cell marker. The CD3 molecule consists of five different polypeptide chains with molecular weights ranging from 16 to 28 kDa. The CD3 antigen is first detected in early thymocytes, and its appearance probably represents one of the earliest signs of commitment to the T cell lineage.

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Anti-CD74 B cell Mouse Monoclonal Antibody [clone: LN2]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to CD74. This antibody can be used for the identification of B cell lymphomas and leukemias. It also stains activated neoplastic cells in T cell lymphomas and Sternberg-Reed cells.

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Anti-Alpha Actinin Mouse Monoclonal Antibody [clone: EA-53]

Supplier: Diagnostic Biosystems
Description: This antibody is specific for α-skeletal muscle actinin and α-cardiac actinin. It stains Z lines and dots in stress fibers of myotubes in skeletal and cardiac muscle but not in non-sarcomeric muscle elements.

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Anti-NKX3-1 Mouse Monoclonal Antibody [clone: 361]

Supplier: Diagnostic Biosystems
Description: The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.

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Anti-Chromogranin A Rabbit Monoclonal Antibody [clone: SP12]

Supplier: Diagnostic Biosystems
Description: Chromogranin A is a 439 amino acid protein present in secretory granules of a wide variety of endocrine cells and neurons. A positive staining is seen in the secretory granules of parathyroid, adrenal medulla, anterior pituitary gland and Langerhans islets of pancreas. This antibody stains a variety of neuroendocrine tumors.

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Anti-Cytokeratin wide spectrum Rabbit Polyclonal Antibody

Supplier: Diagnostic Biosystems
Description: This antibody reacts with cytokeratins of 58, 56, 52, 60, 51, 48 and 68 kDa MW. This antibody is well suited for the staining of a broad spectrum of human keratins.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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