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Catalog Number: (76619-448)
Supplier: AFG Bioscience
Description: 2-Azidoethyl β-lactopyranoside 95%


Catalog Number: (AAJ66684-MD)
Supplier: Thermo Scientific Chemicals
Description: Thought to inhibit protein synthesis by inhibiting normal ribosomal functions

Catalog Number: (CA10746-470)
Supplier: Cytiva
Description: Chemiluminescence detection reagent for detection of high to medium abundant proteins.

Supplier: TCI America
Description: N-Succinimidyl Maleimidoacetate, Cas number: 55750-61-3, Molecular Formula: C10H8N2O6, MW: 252.18, Synonyms: AMAS, Maleimidoacetic Acid N-Succinimidyl Ester, N-(A-Maleimidoacetoxy)succinimide, Appearance: White - Almost white solid crystal powder, Size: 100MG

SDS

Catalog Number: (CAAAH60945-MD)
Supplier: Thermo Scientific Chemicals

Catalog Number: (CAAAJ62312-MC)
Supplier: Thermo Scientific Chemicals
Description: Potassium-selective ionophoric cyclodepsipeptide; inhibitor of mitochondrial action

Catalog Number: (CA95046-162)
Supplier: Enzo Life Sciences
Description: The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.


Catalog Number: (CA200062-860)
Supplier: Enzo Life Sciences
Description: Synaptotagmins (Syt) are membrane-trafficking proteins characterized by an N-terminal transmembrane region, a variable linker, and two C-terminal C2-domains, C2A and C2B. At least twelve Synaptotagamins are expressed in vertebrates and can be found in both vesicular and plasma membranes.


Supplier: AFG Bioscience
Description: 4-Aminophenyl α-D-mannopyranoside ≥95%

Catalog Number: (CAAAAL19229-MD)
Supplier: Thermo Scientific Chemicals
Description: Tetrathiafulvalene 97%

Catalog Number: (CAAAAL19074-MD)
Supplier: Thermo Scientific Chemicals
Description: 6-Methoxyindole 98+%

Catalog Number: (76250-260)
Supplier: WIHA TOOLS TE
Description: These drivers has chamfered tip for easy insertion.


Catalog Number: (CA200062-648)
Supplier: Enzo Life Sciences
Description: Hsp27 is one of the most common members of the highly conserved and ubiquitously expressed family of small heat shock proteins (sHsp), which also includes alphaB-crystallin. It is characterized by a conserved C-terminal alpha-crystallin domain consisting of two anti-parallel beta-sheets that promote oligomer formation required for its primary chaperone function as inhibitor of irreversible protein aggregation. Hsp27 oligomerization is modulated by post-translational phosphorylation of Hsp27 at three serine residues, Ser15, Ser78, and Ser82, by a variety of protein kinases including MAPKAPK-3, PKAc-alpha, p70 S6K, PKD I, and PKC-delta. Hsp27 has been shown to inhibit actin polymerization by binding of unphosphorylated Hsp27 monomers to actin intermediate filaments. Anti-apoptotic functions of Hsp27 have also been identified through interactions with DAXX7, activation of Akt, and inhibition of apoptosome formation. Evidence suggests altered expression of Hsp27 is implicated in the pathogenesis of breast, ovarian, and prostate cancer.


Catalog Number: (CA95046-448)
Supplier: Enzo Life Sciences
Description: Golgi SNARE of 28 kDa (GS28), also known as p28 or GOS28, is a 28 kDa integral membrane protein on the surface of the Golgi apparatus that serves as a t-SNARE in ER to Golgi transport. The amino-terminal of GS28 is exposed to the cytosol and is anchored to the cis Golgi via a 20 amino acid carboxyl-terminal hydrophobic tail. GS28 co-immunoprecipitates complexes consisting of Syntaxin 5, Rbet1, Membrin, Rsec22, and Rsly1, and is therefore implicated in ER to-Golgi or intra-Golgi vesicle transport.


Catalog Number: (CAAAAL10401-MD)
Supplier: Thermo Scientific Chemicals
Description: (S)-(+)-2-Hexanol 98%

Catalog Number: (CA95046-004)
Supplier: Enzo Life Sciences
Description: PKA (Protein Kinase A), also known as cAMP-dependent protein kinase, phosphorylates serine or threonine residues in target protein in response to elevated levels of cAMP. Inactive PKA exists as a tetrameric protein composed of two regulatory (R) subunits and two catalytic (C) subunits. Activation occurs when two cAMP molecules bind to each R subunit which causes a conformational change that releases the active C subunits.


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