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Image Unavailable-76117-552

Anti-ASB3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76117-552)
Supplier: Bioss
Description: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
Image Unavailable-A-3440.0025BA

Boc-Glu-OMe

Supplier: Bachem Americas
Description: Sequence: Boc-Glu-OMe

Image Unavailable-A-1920.0025BA

N-(ɑ)-Boc-L-lysine

Supplier: Bachem Americas
Description: Sequence: Boc-Lys-OH

Image Unavailable-TCE1267-50MG

Ethyl (11bR)-4-Amino-2,6-bis(3,5-di-tert-butylphenyl)-4,5-dihydro-3H-cyclohepta[1,2-a:7,6-a']dinaphthalene-4-carboxylate ≥97.0% (by HPLC)

Catalog Number: (TCE1267-50MG)
Supplier: TCI America
Description: Ethyl (11bR)-4-Amino-2,6-bis(3,5-di-tert-butylphenyl)-4,5-dihydro-3H-cyclohepta[1,2-a:7,6-a']dinaphthalene-4-carboxylate, Purity: >97.0%(HPLC), CAS number: 1678540-23-2, MF: C54H63NO2, Molecular Weight: 758.1, Size: 50 MG
Image Unavailable-A-3735.0005BA

Boc-D-allo-Isoleucine

Supplier: Bachem Americas
Description: Sequence: Boc-D-allo-Ile-OH

Product Image-10084-638

Anti-PPIA Rabbit Polyclonal Antibody

Catalog Number: (10084-638)
Supplier: Proteintech
Description: Cyclophilin A, also named as PPIA and Rotamase A, belongs to the cyclophilin-type PPIase family and PPIase A subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. PPIA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.
Product Image-10468-522

Anti-ASB3 Rabbit Polyclonal Antibody

Catalog Number: (10468-522)
Supplier: Bioss
Description: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
Product Image-10091-692

Anti-P53 Rabbit Polyclonal Antibody

Catalog Number: (10091-692)
Supplier: Proteintech
Description: TP53, also named as P53 and NY-CO-13, belongs to the p53 family. It has 9 isoforms. In SDS-Page, the MW is about 53kd. TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. The antibody reacts specifically with 53 kDa protein.
Image Unavailable-E-1420.0005BA

H-Asp(OtBu)-OMe·HCl

Supplier: Bachem Americas
Description: Sequence: H-Asp(OtBu)-OMe · HCl

Image Unavailable-TCM1522-25G

Di-tert-butyl malonate ≥98.0%

Catalog Number: (TCM1522-25G)
Supplier: TCI America
Description: CAS Number: 541-16-2
MDL Number: MFCD00008810
Molecular Formula: C11H20O4
Molecular Weight: 216.28
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 67
Melting point (°C): -6
Flash Point (°C): 88
Specific Gravity (20/20): 0.97

SDS Certificates


Image Unavailable-76078-588

Anti-Prominin 2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76078-588)
Supplier: Bioss
Description: Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
Image Unavailable-76078-586

Anti-Prominin 2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76078-586)
Supplier: Bioss
Description: Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
Image Unavailable-10424-256

Anti-PROM2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10424-256)
Supplier: Bioss
Description: Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
Image Unavailable-10347-794

Anti-ASB2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10347-794)
Supplier: Bioss
Description: The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.
Image Unavailable-A-1440.0001BA

Boc-Thr(tBu)-OH

Supplier: Bachem Americas
Description: Sequence: Boc-Thr(tBu)-OH

Image Unavailable-CA8.14727.1000

Brij® 58 stabilized for synthesis, Sigma-Aldrich®

Supplier: MilliporeSigma
Description: Cas Number 9004-95-9, Stabilised With 2-Tert-Butyl-4-Methoxyphenol And Citric Acid For Synthesis

SDS Certificates

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