You Searched For: trans-4-Fluoro-L-proline

Supplier: Enzo Life Sciences

Description: Plant hormone.

Catalog Number: (102971-638)

Supplier: Adipogen

Description: VASP (vasodilator-stimulated phosphoprotein) is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. VASP is an actin-associated protein involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping proteins. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments and it plays a role in actin-based mobility of Listeria monocytogenes in host cells. It regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. VASP phosphorylation is used to monitor the effect of so-called antiplatelet drugs that reduce platelet reactivity and are used to prevent stent thrombosis, strokes and heart attacks in patients. Phosphorylation of VASP at Ser157 causes a mobility shift in SDS gel electrophoresis from 46 to 50kDa, which has been used as a convenient marker to monitor cyclic nucleotide-dependent protein kinase activity.

Catalog Number: (75834-224)

Supplier: Restek

Description: Consists of 11 components, those are chlorobenzilate, cis-chlordane, trans-chlordane, chloroneb, dcpa methyl ester , etridiazole, hexachlorobenzene, cis-permethrin*, trans-permethrin*, propachlor and trifluralin.

Catalog Number: (TCE0798-25G)

Supplier: TCI America

Description: CAS Number: 121-39-1
MDL Number: MFCD00005123
Molecular Formula: C11H12O3
Molecular Weight: 192.21
Purity/Analysis Method: >90.0% (GC)
Form: Clear Liquid
Boiling point (°C): 152
Flash Point (°C): 113
Specific Gravity (20/20): 1.13
Specific rotation [a]20/D: 0 deg (neat)
Storage Temperature: 0-10°C

SDS

Catalog Number: (10488-738)

Supplier: Bioss

Description: This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq, Jul 2008].

Supplier: Enzo Life Sciences

Description: Antitumor agent.

Catalog Number: (TCC2200-5G)

Supplier: TCI America

Description: CAS Number: 202982-65-8
MDL Number: MFCD00143287
Molecular Formula: C9H6ClFO2
Molecular Weight: 200.59
Purity/Analysis Method: >97.0% (GC,T)
Form: Crystal
Melting point (°C): 215

SDS

Catalog Number: (76700-786)

Supplier: AFG Bioscience

Description: Human Peptidyl Prolyl cis Trans Isomerase C (PPIC) ELISA Kit

Catalog Number: (TCC0975-025G)

Supplier: TCI America

Description: CAS Number: 1866-38-2
MDL Number: MFCD00004384
Molecular Formula: C9H7ClO2
Molecular Weight: 182.60
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Melting point (°C): 164

SDS Certificates

Supplier: Thermo Scientific Chemicals

Description: 3,4-Dichlorocinnamic acid 97%

Certificates

Catalog Number: (CA80055-978)

Supplier: MilliporeSigma

Description: A natural dietary compound reported to have anticarcinogenic and anti-inflammatory properties. A selective, non-competitive inhibitor of 5-lipoxygenase (ID50=3.7µM). Inhibits Ca2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.

SDS Certificates

Supplier: Biotium

Description: This MAb recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this MAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200 kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the MAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This MAb reacts with both normal and malignant epithelia of various tissues including breast and colon.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Supplier: Thermo Scientific Chemicals

Description: 2-Octene cis- and trans-mixture 98%

Certificates

Supplier: TCI America

Description: CAS Number: 1776-53-0
MDL Number: MFCD00191601
Molecular Formula: C7H13NO2
Molecular Weight: 143.19
Purity/Analysis Method: >95.0% (GC,T)
Form: Crystal

SDS

Catalog Number: (75793-504)

Supplier: Prosci

Description: Profilin (PFN1) is a ubiquitous small (12-15kDa) phosphoinositide and poly-L-proline binding protein that plays a role in signal transduction pathways and actin filament dynamics. There are two mammalian profilins with similar biochemical properties. Whereas profilin I appears to be highly expressed in most tissues except for skeletal muscle, profilin II is predominantly expressed in brain and at lower levels also in skeletal muscle, uterus and kidney. Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes. Profilin binding to PIP2 interferes with PIP2 hydrolysis by soluble phospholipase C-gamma, an inhibition that can be overcome by tyrosine phosphorylation of PLC-gamma. Besides actin monomer sequestration and stimulation of actin nucleotide exchange, profilin can also promote cellular actin filament growth. Profilin is involved in the actin dependent intracellular motility of cytopathogenic bacteria, the regulation of cell adhesion and possibly also in linking the actin cytoskeleton and endocytosis. Profilin has been found to associate with defined complexes containing proteins such as Arp2/3 or the Rho/Rac pathways constituents ROCK-II and HEM2/NAP1. Defects in PFN1 are the cause of amyotrophic lateral sclerosis 18 (ALS18).

Supplier: Thermo Scientific Chemicals

Description: Crotonic acid 98%

Certificates