You Searched For: trans-4-Fluoro-L-proline


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Catalog Number: (77436-866)
Supplier: Bioss
Description: Mixed lineage kinases are a family of protein kinases sharing two leucine zipper-like motifs, which are known to mediate protein dimerization, and a kinase domain whose primary structure is similar to both the tyrosine-specific and the serine/threonine-specific kinase classes. Members of the mixed-lineage kinase (MLK) family include MLK1, MLK2, MLK3 and dual leucine zipper kinase, also designated DLK. MLKs are expressed in neuronal cells where they are likely to interact between Rac1/Cdc42, MKK4 and MKK7 in death signaling. The human MLK1 gene maps to chromosome 14q24.3-q31 and is expressed in epithelial tumor cell lines of the colon, breast, and esophagus. The human MLK2 gene maps to chromosome 19 q13.2. and encodes a predicted 954 amino acid, src homology 3 (SH3) domain-containing protein. The human MLK3 gene maps to chromosome 11q13.1-13.3 and encodes a 847 amino acid, SH3 domain- and proline rich region-containing protein. Apoptosis mechanisms rely on MLKs as an upstream intermediate of mitochondrial cytochrome c release and caspase activation.


Catalog Number: (102979-972)
Supplier: Adipogen
Description: Lipoma preferred partner (LPP) is encoded by the preferred fusion partner gene of the high mobility group protein HMGI-C. LPP is frequently affected by chromosomal translocations in a major group of soft tissue lipomas, as well as in a parosteal lipoma and in pulmonary chondroid hamartomas. The resulting fusion proteins comprise three DNA binding domains of HMGI-C fused to two or three C-terminal LIM domains of LPP and a reciprocal product, respectively. Expression of a HMGI-C/LPP fusion protein causes malignant transformation of fibroblasts. Similar to its relatives zyxin and TRIP (thyroid receptor interacting protein 6) / ZRP-1 (zyxin-related protein 1), LPP consists of a N-terminal proline-rich domain followed by three C-terminal LIM domains (double zinc finger structures that are involved in protein-protein interactions). Like the cytoskeletal protein zyxin, LPP localizes to focal adhesions and cell-cell adherens junctions. LPP harbors a nuclear export signal and displays transcriptional activation capacity.


Catalog Number: (TCT1502-010ML)
Supplier: TCI America
Description: CAS Number: 68480-25-1
MDL Number: MFCD00014048
Molecular Formula: C13H26O
Molecular Weight: 198.35
Purity/Analysis Method: >90.0% (GC)
Form: Clear Liquid
Color: Colorless
Flash Point (°C): 110
Specific Gravity (20/20): 0.85

Supplier: TCI America
Description: CAS Number: 3971-31-1
MDL Number: MFCD00134411
Molecular Formula: C8H12O4
Molecular Weight: 172.18
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Melting point (°C): 149
Supplier: TCI America
Description: CAS Number: 78628-80-5
MDL Number: MFCD00145430
Molecular Formula: C21H25N
Molecular Weight: 327.90
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 214
Supplier: TCI America
Description: CAS Number: 459-32-5
MDL Number: MFCD00004395
Molecular Formula: C9H7FO2
Molecular Weight: 166.15
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Melting point (°C): 207

SDS

Catalog Number: (89161-758)
Supplier: Enzo Life Sciences
Description: Synthetic type I pyrethroid. Structurally similar to the protein phosphatase 2B (calcineurin) inhibitors cypermethrin and deltamethrin but weakly active or inactive depending on assay conditions. May be used as a negative control for cypermethrin and deltamethrin (BML-PR101).


Supplier: TCI America
Description: CAS Number: 33130-03-9
MDL Number: MFCD00014376
Molecular Formula: C12H14O5
Molecular Weight: 238.24
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Color: White
Melting point (°C): 173

SDS

Catalog Number: (TCM2363-25G)
Supplier: TCI America
Description: CAS Number: 16409-43-1
MDL Number: MFCD00036607
Molecular Formula: C10H18O
Molecular Weight: 154.25
Purity/Analysis Method: >97.0% (GC)
Form: Clear Liquid
Boiling point (°C): 88
Flash Point (°C): 65
Specific Gravity (20/20): 0.88

Catalog Number: (TCT2706-5G)
Supplier: TCI America
Description: CAS Number: 30129-18-1
MDL Number: MFCD00102144
Molecular Formula: C7H11F3O
Molecular Weight: 168.16
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Color: Colorless
Boiling point (°C): 181
Specific Gravity (20/20): 1.23

SDS


Supplier: TCI America
Description: CAS Number: 90676-25-8
MDL Number: MFCD00019331
Molecular Formula: C9H18O
Molecular Weight: 142.24
Purity/Analysis Method: >90.0% (GC)
Form: Clear Liquid
Specific Gravity (20/20): 0.92

SDS

Supplier: TCI America
Description: CAS Number: 23528-44-1
Molecular Formula: C14H12S2
Molecular Weight: 244.37
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Boiling point (°C): 166
Melting point (°C): 48
Storage Temperature: 0-10°C

SDS

Supplier: Biotium
Description: This MAb recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this MAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200 kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the MAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This MAb reacts with both normal and malignant epithelia of various tissues including breast and colon.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Supplier: Biotium
Description: This MAb recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this MAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200 kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the MAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This MAb reacts with both normal and malignant epithelia of various tissues including breast and colon.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Catalog Number: (TCB0655-025G)
Supplier: TCI America
Description: CAS Number: 103-64-0
MDL Number: MFCD00000185
Molecular Formula: C8H7Br
Molecular Weight: 183.05
Purity/Analysis Method: >95.0% (GC)
Form: Clear Liquid
Flash Point (°C): 120
Specific Gravity (20/20): 1.42
Storage Temperature: 0-10°C

Catalog Number: (10164-626)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to Trans-Hydroxyproline


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