You Searched For: trans-4-Fluoro-L-proline

Catalog Number: (10371-896)

Supplier: Bioss

Description: Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. Target proteins are preferencially recognized via a LXXLAP motif.

Supplier: Thermo Scientific Chemicals

Description: trans-Cinnamaldehyde 98+%

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Supplier: TCI America

Description: CAS Number: 37951-12-5
MDL Number: MFCD00014901
Molecular Formula: C19H18O3
Molecular Weight: 294.35
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 129
Lambda max.: 357 nm (THF)

SDS

Catalog Number: (10423-786)

Supplier: Bioss

Description: Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.

Catalog Number: (CAPIPA5-18548)

Supplier: Thermo Scientific

Description: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.

Catalog Number: (10423-328)

Supplier: Bioss

Description: Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.

Catalog Number: (10423-326)

Supplier: Bioss

Description: Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.

Catalog Number: (10423-330)

Supplier: Bioss

Description: Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.

Supplier: Thermo Scientific Chemicals

Description: trans-4-Aminocyclohexanol hydrochloride 97%

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Supplier: TCI America

Description: 4-(trans-4-Propylcyclohexyl)cyclohexanone, Purity: >98.0%(GC), CAS Number: 82832-73-3, Molecular Formula: C15H26O, Molecular Weight: 222.37, Size: 1G

Supplier: TCI America

Description: Trans-Crotononitrile, CAS Number: 627-26-9, Purity: 75.0%, Molecular Formula: C4H5N, Molecular Weight: 67.09 g/mol, Synonyms: trans-2-Butenenitrile (contains ca. 20% cis- isomer), Physical Form: Liquid, Size: 100ML

SDS

Catalog Number: (TCP2363-5G)

Supplier: TCI America

Description: 4-(trans-4-Pentylcyclohexyl)phenylboronic Acid, CAS Number: 143651-26-7, Molecular Formula: C17H27BO2, Molecular Weight: 274.21, Synonyms: 4-(trans-4-Pentylcyclohexyl)benzeneboronic Acid, Size: 5G

Supplier: Thermo Scientific Chemicals

Description: trans-2-Hexenoic acid 96%

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Catalog Number: (AAH62938-03)

Supplier: Thermo Scientific Chemicals

Description: trans-3-Cyanocyclohexylamine hydrochloride, 97%

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Catalog Number: (76078-522)

Supplier: Bioss

Description: Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.

Supplier: Thermo Scientific Chemicals

Description: trans,trans-Muconic acid (trans,trans-1,3-butadiene-1,4-dicarboxylic acid) 98+%

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