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Anti-KRT77 & KRT76 Mouse Monoclonal Antibody (CF405S) [clone: AE-1 / AE-3]

Supplier: Biotium
Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67 kDa (CK1); 64 kDa (CK3); 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56.5 kDa (CK10); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE-1/AE-3 is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Image-CA77591-840

Monarch® Spin DNA Gel Extraction Kits

Catalog Number: (CA77591-840)
Supplier: New England Biolabs (NEB)
Description: The Monarch® spin DNA gel extraction kit, a newer version of our original gel extraction kit, offers an efficient method for DNA gel extraction and purification, enabling up to 5 μg of high-quality DNA.

New Product


Image Unavailable-CA82021-384

Accessories for InGel™ Silver for Protein Digestion, G-Biosciences

Supplier: G-Biosciences
Description: Suitable for 100 protein spots. provides optimal buffered conditions for in gel trypsin digestion of proteins.

Product Image-470230-570

Accuris SmartDoc™ 2.0 Imaging System

Supplier: Ward's
Description: An imaging system for your smart phone… Now That's Smart!

Product Image-77001-122

Zymoclean™ Gel DNA Recovery Kits, Zymo Research

Supplier: Zymo Research
Description: The Zymoclean Gel DNA Recovery Kits provide for the rapid purification of high quality DNA from TAE/TBE-bufffered agarose gels.

Product Image-CA95040-080L

Amersham ECL Plex Fluorescent Rainbow Markers, Cytiva

Supplier: Cytiva
Description: Amersham™ ECL™ Plex™ fluorescent Rainbow™ markers are protein molecular weight markers optimised for use with the ECL™ Plex™ Western blotting detection system. They are designed to provide visible marker bands on gels and membranes, as well as fluorescent images using Cy3 and Cy5 channels.

SDS Certificates

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RP Modified TLC Silica Gel 60 Sheets and Plates, MilliporeSigma

Supplier: MilliporeSigma
Description: RP-modified plates serve two purposes: Act as a pilot method for HPLC and allow to choose various solvent system for special separations

Certificates

Image Unavailable-89350-012

Anti-Thymine Dimer Mouse Monoclonal Antibody

Catalog Number: (89350-012)
Supplier: Genetex
Description: Non-radioactive labeling of DNA is typically based on the enzymatic incorporation of modified nucleotides, carrying a small chemical moiety such as biotin, digoxigenin or fluorescein. These tags are subsequently detected by specific reagents such as streptavidin or a specific antibody coupled to a signal-producing enzyme. Although very efficient and reliable, labeling by in vitro polymerization is time-consuming, expensive, and may require various post-label purification steps to remove an excess of unincorporated precursors. An alternative strategy for DNA labeling, is based on the UV-induced formation of cyclobutane thymine dimers. Several methods have been described for the detection of thymine dimers, which are based on chromato-graphic analysis, and on biochemical analysis with endonucleases specific for UV-irradiated DNA. In addition, methods utilizing antibodies specific for pyrimidine dimers and other UV-induced DNA lesions have evolved, which permit the study of the induction and repair of these lesions without the requirement of in vivo radiolabeling of DNA. Photoimmunodetection, is a rapid, reliable and low-cost supplement to existing methods for nonradioactive DNA labeling. It enables a sensitive and non-radioactive method for labeling, detection, and quantification of high molecular weight (HMW) DNA fragments. The method is based on the introduction of thymine dimers into DNA after separa-tion by pulse field gel electrophoresis (PFGE), followed by detection with thymine dimer specific antibodies. The method does not require any enzymatic or chemical manipulation of the DNA sample. Monoclonal anti-bodies reacting specifically with thymine dimer, facilitate investigations on the apoptotic process and the role of UV-induced pyrimidine dimers in the process of photocarcinogenesis.
Product Image-CA90001-062

BD BBL™ Microbiological Specimen Collection and Transport Systems, BD Diagnostics

Supplier: BD
Description: Keep samples viable during transport with convenient, self-contained BD CultureSwab™ and BD CultureSwab Plus™ systems

Certificates

Product Image-CA82021-586

InGel™ Silver for Protein Digestion, G-Biosciences

Catalog Number: (CA82021-586)
Supplier: G-Biosciences
Description: G-Biosciences' InGel™ Silver provides a complete set of reagents for the in gel tryptic digestion and extraction of peptides for mass spectrometry (MALDI and LC MS/MS)
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Anti-KRT Mouse Monoclonal Antibody (CF488A) [clone: KRT7/760 / KRT17/ 778 / KRT18/834 / KRTL/828 / KRTH/829 / KRT/457]

Supplier: Biotium
Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67 kDa (CK1); 64 kDa (CK3); 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 55 kDa (CK7); 52 kDa (CK8); 56.5 kDa (CK10); 53 kDa (CK13); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 46 kDa (CK17); 45 kDa (CK18) and 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Product Image-IC08823051

Human Albumin, MP Biomedicals

Catalog Number: (IC08823051)
Supplier: MP Biomedicals
Description: Albumin may be used to eliminate background interference in ELISA's or other enzyme assay systems. It is also used in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells. Human and bovine albumins contain 16% nitrogen and are often used as standards in protein calibration studies. Due to their free hydrophobic region fatty acid free albumins are used to solubilize lipids in tissue culture, and are also used as blocking agents in Western blots or ELISA applications. Globulin free albumins are suitable for use in applications where no other proteins should be present (e.g., electrophoresis).
Product Image-95026-902

UVP PhotoDoc-It™ Imaging Systems, Analytik Jena

Supplier: Analytik Jena US
Description: The UVP PhotoDoc-It™ systems are designed for fluorescence imaging. The stand-alone systems include a transilluminator, filter, camera, printer and darkroom; no computer is required.

Small Business Enterprise Product available on GSA Advantage®

Image Unavailable-CA89167-892

InGel™ Blue for Protein Digestion, G-Biosciences

Catalog Number: (CA89167-892)
Supplier: G-Biosciences
Description: G-Biosciences' InGel™ Blue kit provides a complete set of reagents for the in gel tryptic digestion and extraction of peptides for mass spectrometry (MALDI and LC MS/MS)

SDS


Product Image-76020-590

Zymoclean™, Gel RNA Recovery Kit, Zymo Research

Catalog Number: (76020-590)
Supplier: Zymo Research
Description: The Zymoclean™ Gel RNA Recovery Kit provides a quick purification method for recovery of RNA fragments from agarose gels.
Product Image-10014-520

PCR and Gel Clean-up Kit, Enzo Life Sciences

Supplier: Enzo Life Sciences
Description: Quick, easy kit for purifying DNA from PCR, gels and labeling reactions for a variety of downstream applications.

SDS

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