Anti-KRT Mouse Monoclonal Antibody (CF488A) [clone: KRT7/760 / KRT17/ 778 / KRT18/834 / KRTL/828 / KRTH/829 / KRT/457]

Supplier: Biotium

BNC880999-100 BNC880999-500
75968-028EA 325.12 CAD
75968-028 75968-030
Anti-KRT Mouse Monoclonal Antibody (CF488A) [clone: KRT7/760 / KRT17/ 778 / KRT18/834 / KRTL/828 / KRTH/829 / KRT/457]
Antibodies
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67 kDa (CK1); 64 kDa (CK3); 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 55 kDa (CK7); 52 kDa (CK8); 56.5 kDa (CK10); 53 kDa (CK13); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 46 kDa (CK17); 45 kDa (CK18) and 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: KRT
Clonality: Monoclonal
Clone: Clone KRT7/760 / KRT17/ 778 / KRT18/834 / KRTL/828 / KRTH/829 / KRT/457
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Chicken, Cow, Dog, Human, Monkey, Mouse, Rabbit, Rat
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