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Image Unavailable-10481-412

Anti-PRDX2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10481-412)
Supplier: Bioss
Description: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.
Image Unavailable-10481-402

Anti-PRDX2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (10481-402)
Supplier: Bioss
Description: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.
Image Unavailable-76109-024

Anti-Peroxiredoxin 2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76109-024)
Supplier: Bioss
Description: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.
Image Unavailable-77438-268

Anti-OXR1 Rabbit Polyclonal Antibody

Catalog Number: (77438-268)
Supplier: Bioss
Description: Reactive oxygen species (ROS) are highly reactive molecules that are a normal consequence of aerobic metabolism. Cellular ROS damage can induce apoptosis and spontaneous mutagenesis. Oxr1 (Oxidation resistance protein 1) is a 758 amino acid mitochondrial protein that is most likely involved in protection from oxidative damage. Oxr1 is highly conserved from yeast to humans and is specific to eukaryotes.Induced by heat and oxidative stress, the carboxyl-terminal half of Oxr1 is required for its function. Upregulation of superoxide dismutase and catalase was observed in developing drosophila mutants that lacked the gene encoding Oxr1, suggesting that oxidative stress may trigger compensatory protein expression. There are four isoforms of Oxr1 that are produced as a result of alternative splicing events.
Image Unavailable-CAAAAB24911-06

2-(Tributylstannyl)pyridine tech. 80%, Technical Grade

Supplier: Thermo Scientific Chemicals
Description: 2-(Tributylstannyl)pyridine tech. 80%, Technical Grade

Certificates

Product Image-470302-208

Potassium Nitrite

Supplier: Ward's Science
Description: CAS Number: 7758-09-0
Formula Weight: 85.11
Formula: KNO2
Hazard Info: Oxidizer, Flammable, Irritant
Density (g/mL): 1.915
Boiling Point (°C): Explodes at 538
Solubility: Water
Synonyms: Nitrous Acid, Potassium Salt
Shelf Life (months): 36
Storage: Yellow

SDS

Image Unavailable-CAAAAL17280-06

3-(Trifluoromethyl)pyridine 97%

Supplier: Thermo Scientific Chemicals
Description: 3-(Trifluoromethyl)pyridine 97%

Certificates

Image Unavailable-CAAAA13590-0B

4-(3-Phenylpropyl)pyridine 98%

Supplier: Thermo Scientific Chemicals
Description: 4-(3-Phenylpropyl)pyridine 98%

Certificates

Product Image-76716-110

Human Lectin-like Oxidized low density Lipoprotein Receptor 1(LOX1) ELISA Kit

Catalog Number: (76716-110)
Supplier: AFG Bioscience
Description: Human Lectin-like Oxidized low density Lipoprotein Receptor 1(LOX1) ELISA Kit
Product Image-77663-936

Accessories for Nitric Oxide Macro Sensor

Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: Accessories for Nitric Oxide Macro Sensor

New Product

Image Unavailable-TCH1528-5G

2-(Trifluoromethyl)pyridin-4-ol ≥98.0% (by GC, titration analysis)

Supplier: TCI America
Description: 4-Hydroxy-2-(trifluoromethyl)pyridine, Purity: >98.0%(GC)(T), CAS No: 170886-13-2, Molecular Formula: C6H4F3NO, Molecular Weight: 163.1, Synonym: 2-(Trifluoromethyl)-4-pyridinol, Physical state: Solid, Form: Crystal - Powder, Colour: White - Yellow, Size: 1G

SDS

Image Unavailable-89359-612

Anti-HO-1 Mouse Monoclonal Antibody [clone: HO-1-1]

Catalog Number: (89359-612)
Supplier: Genetex
Description: Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules, biliverdin and carbon monoxide. HO consists of two homologous isozymes, an inducible HO1 and a constitutively expressed HO2. HO1 is induced by a wide variety of stimuli including conditions of oxidative stress, inflammatory agents, transforming growth factor beta and heat shock. The increase in expression of HO1 is thought to be a cellular defense mechanism against oxidative stress since elevated HO could eventually generate more bilirubin, an anti-oxidant.
Image Unavailable-CAAA12290-A9

Diboron trioxide ≥97.5% (typ. 98.5%)

Supplier: Thermo Scientific Chemicals
Description: As a flux, acid catalyst, or chemical intermediate in production of boron halides, esters, carbide, nitride, and metallic borides

Certificates

Image Unavailable-CAAA41673-30

Zinc titanate ≥99.9% (metals basis)

Supplier: Thermo Scientific Chemicals
Description: Zinc titanate ≥99.9% (metals basis)

Certificates

Image Unavailable-CAAAAL17548-14

Fomblin® YR-1800

Supplier: Thermo Scientific Chemicals
Description: Fomblin® YR-1800

Certificates

Product Image-89011-858

AlphaTec® Butyl 38-514 Chemical resistant gloves, Ansell

Supplier: Ansell Canada
Description: These gloves deliver superior resistance to esters, ketones, and oxidizing agents, including concentrated oxidizing mineral acids such as 70% nitric acid and 98% sulfuric acid.

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