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Product Image-76262-724

Anti-TP53 Rabbit Polyclonal Antibody

Catalog Number: (76262-724)
Supplier: Rockland Immunochemical
Description: TP53 (tumor suppressor gene p53) is one of the most well-studied genes that suppresses tumor formation and renders protection against DNA damage by inducing cell cycle arrest, DNA repair, or apoptosis. TP53 signaling is triggered through numerous cellular events ranging from DNA damage to hypoxia, stress and a plethora of other causes. Upon activation, p53 acts as zinc-containing transcriptional regulator and initiates a cascade of events that determines the cellular outcome including cell cycle arrest, apoptosis, senescence, DNA repair, development, differentiation and tissue homeostasis. Cell cycle arrest is induced by p53 via trans-activating genes such as p21 (CDK-inhibitor 1, cyclin dependent kinase) and others. Interestingly, p53 itself is capable of triggering cellular responses (survival or induced cell death) as well. Mutations or deletions in the TP53 gene are present in nearly 50% of human cancers, and primarily results in impaired tumor suppressor function. Anti-p53 (ac Lys292) antibody is ideal for researchers interested in developmental biology, cell growth and cancer research.
Image Unavailable-10750-120

Anti-RVFV_sM_gp1 Rabbit Polyclonal Antibody

Catalog Number: (10750-120)
Supplier: Prosci
Description: Rift Valley Fever Virus Antibody: Rift Valley Fever (RFV) virus is an arthropod-borne virus endemic to Africa that infects humans and animals that is transmitted predominantly by mosquitoes. During human infections, symptoms can range from benign fever to severe encephalitis and fatal hepatitis with hemorrhagic fever. The Bunyaviridae family of viruses to which the RVF virus belongs are spherical enveloped viruses with a tripartite RNA genome of negative or ambisense polarity. The three segments are referred to as the L, M, and S segments. The L and M segments are negative polarity and code fore the L-dependent RNA polymerase and glycoprotein precursor respectively. The S segment is of ambisense polarity and encodes the nucleoprotein and non-structural proteins. This RVF virus antibody was derived from a peptide sequence near the center of the polyprotein precursor translated from the M segment. It will therefore detect both the precursor and the Glycoprotein G1.
Product Image-14225-926

SGE BP10 GC Capillary Columns

Supplier: Trajan Scientific and Medical
Description: The SGE BP10 GC Capillary Column provides a great mid-polarity option for analyses. Recommended for: Environmental analysis (EPA methods 608, 8081), pesticides/herbicides, drugs of abuse, pharmaceuticals.

Product Image-10106-340

Anti-ZFP91 Rabbit Polyclonal Antibody

Catalog Number: (10106-340)
Supplier: Prosci
Description: The protein encoded by ZFP91 is a member of the zinc finger family of proteins. This protein contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins.The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. In addition to the monocistronic transcript originating from this locus, a co-transcribed variant composed of ZFP91 and CNTF sequence has been identified. The monocistronic and co-transcribed variants encode distinct isoforms. The co-transcription of ZFP91 and CNTF has also been observed in mouse.
Product Image-CA62409-300

Nunc-Immuno™ and Fluoronunc™/Luminunc™ 96-Well Modules and Frames, Thermo Scientific

Supplier: Thermo Fisher Scientific
Description: Composed of individual modules consisting of either 8, 12, or 16 wells, these plates are designed specifically for quantitative immunoassays and solid phase assays

Image Unavailable-75779-264

Uniliner® Inlet Liner with Top Taper for Agilent GCs equipped with split/splitless inlets, Restek

Catalog Number: (75779-264)
Supplier: Restek
Description: Use of these liners helps ensure an inert GC flow path for higher sensitivity, accuracy, and reproducibility.
Image Unavailable-10339-624

Anti-ATP4B Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10339-624)
Supplier: Bioss
Description: Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity.
Image Unavailable-CA10037-368

Anti-CDKN1B Rabbit Polyclonal Antibody

Catalog Number: (CA10037-368)
Supplier: Rockland Immunochemical
Description: Anti-p27kip1 pS140 antibody is suitable for use in ELISA, immunoprecipitation, co-immunoprecipitation and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band at ~27 kDa in size corresponding to p27.
Product Image-10215-474

BRANDplates® Insert System for Cell Culture, BrandTech®

Supplier: Brandtech
Description: BRANDplates® Insert System includes a choice of two types of cell culture plates and two types of cell culture inserts for co-culture, migration/invasion assays, chemotaxis assays, and 3D tissue preparation.

Product Image-89150-970

Zinc protoporphyrin ≥95% (by TLC)

Supplier: Enzo Life Sciences
Description: Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter.

Image Unavailable-75967-580

Anti-TP53 Mouse Monoclonal Antibody (CF640R) [clone: BP53-12 DO-7]

Supplier: Biotium
Description: This antibody recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 under denaturing and non-denaturing conditions. Its epitope maps within the N-terminus (aa 20-25) of p53 oncoprotein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Image Unavailable-77564-450

Human Recombinant Tau-441, PKA-phosphorylated (from E. coli)

Supplier: Sino Biological
Description: Recombinant human tag-free Tau-441 was co-expressed with PKAc alpha in <i>E. coli</i> cells. The Tau-441 protein was phosphorylated by PKAc alpha <i>in vivo </i>and<i> in vitro</i> prior to the final chromatography purification.

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Product Image-CA100-401-A04

Anti-CUL4A Rabbit Monoclonal Antibody [clone: 8A3]

Catalog Number: (CA100-401-A04)
Supplier: Rockland Immunochemical
Description: This antibody reacts with human Cul4A by western blot and immunoprecipitation.  The antibody immunoprecipitates Protein from cell lysates (using HeLa, U2OS and others).  This antibody also co-immunoprecipitates at least 8 subunits of COP9, DDB1 and CAND1.
Image Unavailable-10671-620

Anti-DVL2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10671-620)
Supplier: Bioss
Description: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity).
Image Unavailable-10671-616

Anti-DVL2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10671-616)
Supplier: Bioss
Description: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity).
Image Unavailable-77439-072

Anti-Tau Rabbit Polyclonal Antibody

Catalog Number: (77439-072)
Supplier: Bioss
Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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  • issued document with your organization's Federal Tax ID Number
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