Print…

You Searched For: PJ-34+hydrochloride


5,555  results were found

Refine Results Sort by
SearchResultCount:"5555"

Sort Results

List View Easy View

Rate These Search Results

Product Image-89147-574

PJ-34 hydrochloride (synthetic) ≥98% (by HPLC)

Supplier: Enzo Life Sciences
Description: Potent, water soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC50=20nM compared to EC50=200µM of the prototypical PARP inhibitor 3-aminobenzamide). Inhibits peroxynitrite-induced cell necrosis (EC50=20nM). Has significant, dose-dependent, anti-inflammatory effects in a variety of local inflammation models and provides cardioprotection by decreasing myocardial infarct size.

Image Unavailable-CAAAJ64413-MB

PJ-34 hydrochloride

Supplier: Thermo Scientific Chemicals
Description: A cell-permeable, water-soluble phenanthridinone-derivative that acts as a potent inhibitor of poly(ADP-ribose) polymerase

Certificates

Product Image-10089-724

Anti-STK11 Rabbit Polyclonal Antibody

Catalog Number: (10089-724)
Supplier: Proteintech
Description: STK11(serine/threonine-protein kinase 11) is also named as LKB1,PJS,and belongs to the protein kinase superfamily. It controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response.The tumour suppressor protein LKB1 is a serine/threonine kinase that has been causally linked to Peutz-Jeghers syndrome (PJS).Defects in STK11 are a cause of Peutz-Jeghers syndrome (PJS) and defects in STK11 have been associated with testicular germ cell tumor (TGCT) and some sporadic cancers, especially lung cancers.
Image Unavailable-10371-228

Anti-CAB39 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10371-228)
Supplier: Bioss
Description: Mouse protein 25 alpha (MO25 alpha, CAB39) is a 40-kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. The latter is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS). CAB39 binds directly to a conserved Trp-Glu-Phe sequence at the STRAD alpha C terminus, markedly enhancing binding of STRAD alpha to LKB1 and increasing LKB1 catalytic activity. Skeletal muscle contraction results in the phosphorylation and activation of the AMP-activated protein kinase (AMPK) by an upstream kinase (AMPKK). The LKB1-STE-related adaptor (STRAD)-mouse protein 25 (MO25) complex is the major AMPKK in skeletal muscle; however, LKB1-STRAD-MO25 activity is not increased by muscle contraction. This relationship suggests that phosphorylation of AMPK by LKB1-STRAD-MO25 during skeletal muscle contraction may be regulated by allosteric mechanisms.
Image Unavailable-10371-232

Anti-CAB39 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10371-232)
Supplier: Bioss
Description: Mouse protein 25 alpha (MO25 alpha, CAB39) is a 40-kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. The latter is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS). CAB39 binds directly to a conserved Trp-Glu-Phe sequence at the STRAD alpha C terminus, markedly enhancing binding of STRAD alpha to LKB1 and increasing LKB1 catalytic activity. Skeletal muscle contraction results in the phosphorylation and activation of the AMP-activated protein kinase (AMPK) by an upstream kinase (AMPKK). The LKB1-STE-related adaptor (STRAD)-mouse protein 25 (MO25) complex is the major AMPKK in skeletal muscle; however, LKB1-STRAD-MO25 activity is not increased by muscle contraction. This relationship suggests that phosphorylation of AMPK by LKB1-STRAD-MO25 during skeletal muscle contraction may be regulated by allosteric mechanisms.
Product Image-89416-158

Anti-STK11 Rabbit Polyclonal Antibody

Catalog Number: (89416-158)
Supplier: Prosci
Description: LKB1 Antibody: The LKB1 serine/threonine protein kinase was initially identified as a tumor suppressor gene mutated in human Peutz-Jeghers syndrome (PJS), a condition resulting in the growth of numerous intestinal polyps classed as hamartomas. LKB1 exists as a heterotrimeric complex with two other proteins, Ste20-related adaptor protein (STRAD) and MO25. Together, this complex can phsophorylate and activate the AMP-activate protein kinase (AMPK). Following AMPK activation by LKB1, AMPK then phosphorylates TSC1 and TSC2, key components of the metabolism-regulating TOR signaling pathway, which antagonizes the activation for the TOR pathway. LKB1 has also been shown to play a fundamental role in controlling the spatial orientation of structures required to maintain an ordered, polarized epithelium.
Image Unavailable-10371-230

Anti-CAB39 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10371-230)
Supplier: Bioss
Description: Mouse protein 25 alpha (MO25 alpha, CAB39) is a 40-kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. The latter is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS). CAB39 binds directly to a conserved Trp-Glu-Phe sequence at the STRAD alpha C terminus, markedly enhancing binding of STRAD alpha to LKB1 and increasing LKB1 catalytic activity. Skeletal muscle contraction results in the phosphorylation and activation of the AMP-activated protein kinase (AMPK) by an upstream kinase (AMPKK). The LKB1-STE-related adaptor (STRAD)-mouse protein 25 (MO25) complex is the major AMPKK in skeletal muscle; however, LKB1-STRAD-MO25 activity is not increased by muscle contraction. This relationship suggests that phosphorylation of AMPK by LKB1-STRAD-MO25 during skeletal muscle contraction may be regulated by allosteric mechanisms.
Image Unavailable-F-1500.0250BA

H-3,4-DehydroPro-OMe hydrochloride

Supplier: Bachem Americas
Description: Sequence: H-3,4-Dehydro-Pro-OMe · HCl

Image Unavailable-TCD4629-1G

6,7-Dimethoxy-3,4-dihydroisoquinoline hydrochloride ≥98.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: 6,7-Dimethoxy-3,4-dihydroisoquinoline Hydrochloride, Purity: >98.0%(HPLC)(T), CAS Number: 20232-39-7, Molecular Formula: C11H13NO2.HCl, Molecular Weight: 227.69, Form: Crystal-Powder, Solid, Color: Pale yellow - Yellow, Size: 5G

SDS

Image Unavailable-TCC3015-50MG

Carteolol hydrochloride ≥98.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: Carteolol Hydrochloride, CAS Number: 51781-21-6, Purity: 98.0%, Molecular Formula: C16H24N2O3.HCl, Molecular Weight: 328.84, Synonyms: 5-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-2(1H)-quinolinone Hydrochloride, Physical Form: Solid, Size: 250MG

SDS

Image Unavailable-TCI0948-5G

Itopride hydrochloride ≥98.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: Itopride Hydrochloride, Purity: >98.0%(HPLC)(T), CAS number: 122892-31-3, Molecular Formula: C20H26N2O4.HCl, Molecular Weight: 394.9, Synonym: N-[4-[2-(Dimethylamino)ethoxy]benzyl]-3,4-dimethoxybenzamide Hydrochloride, Size: 1G

Image Unavailable-TCB5372-1G

Bevantolol hydrochloride ≥98.0% (by HPLC)

Supplier: TCI America
Description: Bevantolol Hydrochloride, Purity: >98.0%(HPLC), CAS Number: 42864-78-8, Molecular Formula: C20H27NO4·HCl, Molecular Weight: 381.90, Synonyms: 1-[(3,4-Dimethoxyphenethyl)amino]-3-(m-tolyloxy)propan-2-ol Hydrochloride, Size: 250MG

Image Unavailable-CAAAA13027-18

3,4-Dimethylphenylhydrazinium chloride 98%

Supplier: Thermo Scientific Chemicals
Description: 3,4-Dimethylphenylhydrazinium chloride 98%

Certificates

Image Unavailable-CAAAH33697-03

2-Chloro-3,4-dimethoxypyridine hydrochloride 97%

Catalog Number: (CAAAH33697-03)
Supplier: Thermo Scientific Chemicals

Certificates


Image Unavailable-TCM2479-100MG

Moxifloxacin hydrochloride monohydrate ≥98.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: Moxifloxacin Hydrochloride Monohydrate, >98%, 192927-63-2, C21H24FN3O4.HCl.H2O, Synonym: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic Acid Hydrochloride Monohydrate, Size: 1G

Certificates

Image Unavailable-CAAAJ61535-03

Verapamil hydrochloride 99+%

Catalog Number: (CAAAJ61535-03)
Supplier: Thermo Scientific Chemicals
Description: A calcium channel blocker with a chemopreventive character

Certificates


Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
You must log in to order restricted items. We request that you provide the required business documentation to purchase this product for the first time.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
  • Government issued document with your organization's Resale Tax ID Number
  • Any other Government ID that includes the business name and address


VWR will not lift restrictions for residential shipping addresses.

-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is currently unavailable but limited stock may be available in our extended warehouse network. Please call 1-800-932-5000 and a VWR Customer Service Representative will help you.
1 - 16 of 5,555
no targeter for Bottom