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Supplier: Trajan Scientific and Medical
Description: SGE understands how important your MS results are and how precious your sample is, so we engineered new syringes and needles to bring you the Diamond MS Syringe range. Diamond MS syringes and needles are MS ready and designed to improve the sensitivity of your MS results.

Catalog Number: (CA76518-678)
Supplier: Beckman Coulter
Description: The EMnetik Plasmid Purification Kit is a revolutionary bead-based DNA cleanup kit. Using new SuperSPRI bead technology combined with the microparticle processor EMnetik 24, a user can complete a plasmid prep without having to handle columns.


Catalog Number: (77438-024)
Supplier: Bioss
Description: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.


Catalog Number: (10664-430)
Supplier: Bioss
Description: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.


Supplier: Bachem Americas
Description: Hepcidin-25 (hepatic bactericidal protein), also referred to as LEAP-1 (liver-expressed antimicrobial peptide) has been independently discovered by two groups in human blood ultrafiltrate and urine. The peptide which is predominantly expressed in the liver, belongs to a new vertebrate family of small antimicrobial peptides that contain 8 cysteine residues and show significant antibacterial and antifungal activity. Further investigations revealed that hepicidin is the principal iron-regulatory hormone in humans. It acts by binding to the iron exporter ferroportin, inducing its internalization and degradation, thereby blocking cellular iron efflux. Nemeth et al. demonstrated that the N-terminal part of the peptide hormone is essential for its activity.
Synonym: Hepc25 (human), LEAP-1 (human), Liver-Expressed Antimicrobial Peptide (human), PLTR (human), Putative Liver Tumor Regressor (human)
Sequence: H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH
Salt: Trifluoroacetate
Bonds: (Disulfide bonds between Cys7 and Cys23/Cys10 and Cys13/Cys11 and Cys19/Cys14 and Cys22)

Catalog Number: (10402-796)
Supplier: Bioss
Description: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.


Catalog Number: (10402-808)
Supplier: Bioss
Description: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.


Catalog Number: (10465-728)
Supplier: Bioss
Description: DUSP2 is a dual-specific thr/tyr phosphatase that is a physiologically relevant MAP kinase phosphatase. The gene is located on 2q11.2-q11 and contains 4 exons that span approximately 2.3kb. Under specific stress conditions, p53 regulates transcription of PAC1 through a new p53-binding site, and that PAC1 is necessary and sufficient for p53-mediated apoptosis.


Catalog Number: (10465-736)
Supplier: Bioss
Description: DUSP2 is a dual-specific thr/tyr phosphatase that is a physiologically relevant MAP kinase phosphatase. The gene is located on 2q11.2-q11 and contains 4 exons that span approximately 2.3kb. Under specific stress conditions, p53 regulates transcription of PAC1 through a new p53-binding site, and that PAC1 is necessary and sufficient for p53-mediated apoptosis.


Catalog Number: (10107-932)
Supplier: Prosci
Description: ADARB1 is an enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site.This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.


Catalog Number: (H-4902.0001BA)
Supplier: Bachem Americas
Description: Anticoagulant and antithrombotic peptides. Please see also the product family 'Hirudin Fragments and Analogs', the inhibitors N-1065, N-1215, N-1260, N-1565, and N-1970, and the anticoagulant anisindione, Q-1085.


Catalog Number: (10098-194)
Supplier: Prosci
Description: CTGF (connective tissue growth factor) is a 38kDa, cysteine-rich, secreted peptide. It is a new member of the peptide family that include serum-induced immediate early gene products, a v-src-induced peptide and a putative proto-oncogene. Among the many functions of the CTGF gene family are embryogenesis, wound healing and regulation of extracellular matrix production.


Catalog Number: (CA77147-440)
Supplier: Motic
Description: This new fluorescence bundle includes a Panthera C2 trinocular 50:50 microscope and a FITC filter (fluorescence accessory). If it is about stained sections with cover glass protection, about native smears, fine needle biopsies, blood smears which wanted to be treated with or without cover glass: Panthera C2 is your solution.


Supplier: Diagnostic Biosystems
Description: PTEN gene is a tumor suppressor gene that maps to chromosome 10q23. PTEN, a novel tumor suppressor, functions as a regulator of both cell cycle progression and apoptosis ). Potentially, mutation and deletion of PTEN gene may result in a new signal transduction pathway related to human malignant tumors. Studies have demonstrated a reduction of PTEN expression in advanced breast cancers.

Supplier: Adipogen
Description: Meteorin-like (cometin; subfatin) is a potent new neurotrophic factor promoting neurite outgrowth from dorsal root ganglion cells. Meteorin-like is also a novel adipokine expressed by adipose tissue being downregulated upon caloric restriction. Meteorin-like is secreted by muscles during exercise and converts white adipose cells into brown fat tissue.

Supplier: Lakeland
Description: Lakeland's new high performance FR sweater-knit quarter zip jackets are a soft and comfortable FR pullover ideal for when the weather turns cold. The jacket features modern, flat seam construction with contrasting black threads with the additional benefits of permanent moisture-wicking technology and incredible horizontal stretch will keep wearers comfortable.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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