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Supplier: AFG BIOSCIENCE LLC
Description: 2,4,7,8,9-Penta-O-acetyl-N-acetylneuraminic acid methyl ester 95%

Catalog Number: (TCA1821-1G)
Supplier: TCI America
Description: CAS Number: 22900-11-4
Molecular Formula: C12H21NO9
Molecular Weight: 323.30
Purity/Analysis Method: >95.0% (HPLC)
Form: Crystal
Flash Point (°C): 113
Specific rotation [a]20/D: -27.5 deg (C=1, H2O)
Storage Temperature: <0°C

Catalog Number: (TCA1822-1G)
Supplier: TCI America
Description: CAS Number: 84380-10-9
Molecular Formula: C20H29NO13
Molecular Weight: 491.45
Purity/Analysis Method: >90.0% (HPLC)
Form: Crystal
Storage Temperature: <0°C

SDS


Supplier: AFG BIOSCIENCE LLC
Description: 4,7,8,9-Tetra-O-acetyl-N-acetylneuraminic acid methyl ester ≥95%

Supplier: AFG BIOSCIENCE LLC
Description: 2-​O-​Methyl-​β-​D-​N-​acetylneuraminic Acid ≥95%

Supplier: AFG BIOSCIENCE LLC
Description: 2-O-Methyl-α-D-N-acetylneuraminic acid ≥95%

Catalog Number: (CAAAAL13950-MC)
Supplier: Thermo Scientific Chemicals
Description: N-Acetylneuraminic acid 97%

Catalog Number: (CA80055-610)
Supplier: MilliporeSigma
Description: A component of mucoproteins, mucopolysaccharides and mucolipids.

Catalog Number: (77517-026)
Supplier: AFG BIOSCIENCE LLC
Description: Human NANS (N-Acetylneuraminic Acid Synthase) ELISA Kit

New Product


Supplier: TCI America
Description: CAS Number: 131-48-6
MDL Number: MFCD00006620
Molecular Formula: C11H19NO9
Molecular Weight: 309.27
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Melting point (°C): 186
Specific rotation [a]20/D: -32 deg (C=1, H2O)
Storage Temperature: <0°C
Catalog Number: (89319-380)
Supplier: Genetex
Description: Rabbit polyclonal antibody to NANS (N-acetylneuraminic acid synthase)


Supplier: AFG BIOSCIENCE LLC
Description: N-Acetyl-2,3-didehydro-2-deoxyneuraminic acid ≥95%

Catalog Number: (10099-948)
Supplier: Prosci
Description: Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins.Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).


Catalog Number: (10099-986)
Supplier: Prosci
Description: CMAS is an enzyme that catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.


Catalog Number: (10091-256)
Supplier: Proteintech
Description: The N-acetylneuraminate lyase(NPL) from human (hNAL) which consists of 320 amino acids, has a molecular mass of 35.2 kDa and it catalyses the reversible aldol reaction of sialic acid, and has been extensively used in the synthesis of sialic acids and its analogues. The enzyme is widely distributed and are present in numerous pro- and eukaryotic cells, in which they are localized only in the cytosol. It belongs to the DHDPS family and has 5 isoforms produced by alternative splicing.


Catalog Number: (89417-012)
Supplier: Prosci
Description: ST3gal6 Antibody: Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.


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