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Supplier: TCI America
Description: CAS Number: 112-38-9
MDL Number: MFCD00004442
Molecular Formula: C11H20O2
Molecular Weight: 184.28
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Color: White
Boiling point (°C): 275
Flash Point (°C): 146
Freezing point (°C): 24

SDS

Supplier: Biotium
Description: This antibody recognizes a protein of ~55 kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Supplier: Biotium
Description: This antibody recognizes a protein of ~55 kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Supplier: Ward's Science
Description: CAS Number: 7681-11-0
Formula: KI
Density: 3.12 g/mL
Boiling and Freezing Point: 1330°C, 680°C
Solubility: Water, Glycerin, Alcohol, and Acetone
Shelf Life: 36 Months

SDS

Supplier: Biotium
Description: This antibody recognizes a protein of ~55 kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Catalog Number: (TCM1070-001G)
Supplier: TCI America
Description: CAS Number: 71242-58-5
MDL Number: MFCD00151646
Molecular Formula: C10H18OS
Molecular Weight: 186.31
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 72
Specific rotation [a]20/D: -61 deg (C=2, CHCl3)

Supplier: TCI America
Description: CAS Number: 53463-68-6
MDL Number: MFCD00041681
Molecular Formula: C10H21BrO
Molecular Weight: 237.18
Purity/Analysis Method: >85.0% (GC)
Form: Clear Liquid
Boiling point (°C): 169
Flash Point (°C): 109
Specific Gravity (20/20): 1.16
Storage Temperature: <0°C
Supplier: TCI America
Description: [for Biochemical Research]
CAS Number: 15163-36-7
MDL Number: MFCD00036908
Molecular Formula: C15H33NO3S
Molecular Weight: 307.49
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Melting point (°C): 229
Catalog Number: (10149-448)
Supplier: Immunoreagents
Description: The ImmunoReagents' DyLight® 350 conjugates are a derivative of AMCA (Aminomethylcoumarine acetate), which a blue fluorescent dye commonly is used as a contrasting dye for double- and triple-labeling used in a wide array of applications. The UV-excitable DyLight® 350 has spectral properties that are very similar to those displayed by AMCA, including identical excitation wavelengths and a large stokes shift. The emission wavelength of DyLight® 350 has a 10-nm blue shift over AMCA, though, that provides an advantage in multiplexing with green fluorophores. (Excitation/Emission = 353nm / 432nm Emission Color = Blue (Similar Dyes: Alexa Fluor 350, AMCA)


Catalog Number: (TCM1341-100MG)
Supplier: TCI America
Description: CAS Number: 71242-59-6
MDL Number: MFCD02093482
Molecular Formula: C10H18OS
Molecular Weight: 186.31
Purity/Analysis Method: >97.0% (GC)
Form: Crystal
Melting point (°C): 86
Specific rotation [a]20/D: -6 deg (C=2, CHCl3)

Supplier: TCI America
Description: 9,9-Dimethyl-10-phenyl-9,10-dihydroacridine, Purity: >98.0%(GC), CAS Number: 717880-39-2, Molecular Formula: C21H19N, Molecular Weight: 285.39, Size: 1G

Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
Description: Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 binds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. IL-19 induces interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α) expression in monocytes, and promotes type 2 T helper (Th2) cell-mediated immune responses. IL-19 production is upregulated in resting monocytes following granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide (LPS) stimulation.

Supplier: Biotium
Description: This antibody recognizes a protein of ~55 kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Catalog Number: (TCN0929-1G)
Supplier: TCI America
Description: CAS Number: 597554-03-5
MDL Number: MFCD11973625
Molecular Formula: C24H17BO2
Molecular Weight: 348.21
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal

SDS


Supplier: TCI America
Description: CAS Number: 112-43-6
MDL Number: MFCD00004750
Molecular Formula: C11H22O
Molecular Weight: 170.30
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Color: Colorless
Boiling point (°C): 138
Flash Point (°C): 110
Specific Gravity (20/20): 0.85
Supplier: Biotium
Description: This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi's sarcoma, but with a lower specificity.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

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