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Image Unavailable-10081-934

Anti-ANXA2 Mouse Monoclonal Antibody [clone: 3H1B11]

Catalog Number: (10081-934)
Supplier: Proteintech
Description: Annexin A2 (ANXA2), also named Annexin-2 or Lipocortin II, is a Ca2+ binding protein that is up-regulated in virally transformed cell lines and human tumors. This calcium-regulated membrane-binding protein, whose affinity for calcium is greatly enhanced by anionic phospholipids, may cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis. Heat-stress response may also involve Annexin-2.
Image Unavailable-CA76633-554

Anti-Heat Shock Protein 70 Mouse Monoclonal Antibody [clone: W27]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to constitutive (HSP73) and inducible (HSP72) form of HSP70. HSP70 is found to be associated with steroid receptors, actin, P53, polyoma T antigen, nucleotides and other known proteins. HSP70 has been shown to be involved in protective roles against thermal stress, cytotoxic drugs and other damaging conditions.

Product Image-CA200062-514

Anti-CRYAB Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences
Description: Alpha-crystallins, which are part of the small Heat shock family members, are major water-soluble proteins present in the lens of the mammalian eye. Phosphorylation of serine residues which occurs during development and in response to stress, is intimately linked with its function. Chaperone activity requires, and is modulated by, oligomerization and is limited to binding unfolded intermediates to prevent irreversible aggregation.

Product Image-CA200062-508

Anti-CRYAA Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences
Description: Alpha-crystallins, which are part of the small Heat shock family members, are major water-soluble proteins present in the lens of the mammalian eye. Phosphorylation of serine residues which occurs during development and in response to stress, is intimately linked with its function. Chaperone activity requires, and is modulated by, oligomerization and is limited to binding unfolded intermediates to prevent irreversible aggregation.

Product Image-CA76419-510

Rimadyl® MD Tablets for Rodents

Supplier: Bio-Serv
Description: Rimadyl (carprofen) is an effective anti-inflammatory drug used in a variety of species including rodents. Ideal pain-free alternative to stressful and laborious post-op injections.

Product Image-77578-406

Moisture Analyzers, MB32, MB62 and MB92

Supplier: Ohaus
Description: The next generation of MB series moisture analyzers come in a sleek design offering improved durability and stability in performance, with an upgraded loadcell and carbon fiber heating technology.

New Product

Image Unavailable-10449-348

Anti-HSPA6 Rabbit Polyclonal Antibody

Catalog Number: (10449-348)
Supplier: Bioss
Description: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Sequence similarities Belongs to the heat shock protein 70 family.
Product Image-CA200063-288

Anti-FKBP59 Mouse Monoclonal Antibody [clone: KN382/EC1]

Supplier: Enzo Life Sciences
Description: FKBP59, also known as Hsp56/p59 is an immunophilin that is a component of Hsp70/Hsp90/steroid receptor complexes. Expression of FKBP59 is increased in response to heat shock and ischemic stress, and is thought to play a role in the folding and cytoplasmic/nuclear distribution of steroid receptors.

Product Image-470310-234

10–in–1 Environmental Meter

Catalog Number: (470310-234)
Supplier: NEW GENIE GROUP INC SE
Description: Convenient 10-in-1 Environmental Meter measuring Air Velocity, Air Flow, Air Temperature, Type K Temperature, Heat Index, Humidity, Wet Bulb, Dew Point, Windchill, and Light Level.
Image Unavailable-77438-268

Anti-OXR1 Rabbit Polyclonal Antibody

Catalog Number: (77438-268)
Supplier: Bioss
Description: Reactive oxygen species (ROS) are highly reactive molecules that are a normal consequence of aerobic metabolism. Cellular ROS damage can induce apoptosis and spontaneous mutagenesis. Oxr1 (Oxidation resistance protein 1) is a 758 amino acid mitochondrial protein that is most likely involved in protection from oxidative damage. Oxr1 is highly conserved from yeast to humans and is specific to eukaryotes.Induced by heat and oxidative stress, the carboxyl-terminal half of Oxr1 is required for its function. Upregulation of superoxide dismutase and catalase was observed in developing drosophila mutants that lacked the gene encoding Oxr1, suggesting that oxidative stress may trigger compensatory protein expression. There are four isoforms of Oxr1 that are produced as a result of alternative splicing events.
Image Unavailable-10408-928

Anti-PSMC2 Rabbit Polyclonal Antibody

Catalog Number: (10408-928)
Supplier: Bioss
Description: Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes and the endoplasmic reticulum.
Product Image-CA200062-774

Anti-HSP90B1 Rat Monoclonal Antibody [clone: 9G10]

Catalog Number: (CA200062-774)
Supplier: Enzo Life Sciences
Description: Grp94 (Glucose-regulated protein 94) is an abundant resident endoplasmic reticulum (ER) lumenal stress protein, which together with cytosolic Hsp90 belongs to the Hsp90 family of molecular chaperones. Grp94 expression is upregulated by stress conditions such as glucose starvation and heat shock, which promote protein misfolding or unfolding. In addition to a homeostatic role in protein folding and assembly, Grp94 can function in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells.
Image Unavailable-CAPIPA5-12621

Anti-MAPKAPK5 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-12621)
Supplier: Thermo Scientific
Description: The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites.
Image Unavailable-76118-332

Anti-HSPA6 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76118-332)
Supplier: Bioss
Description: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Sequence similarities Belongs to the heat shock protein 70 family.
Image Unavailable-75953-456

Anti-HSPD1 Mouse Monoclonal Antibody (CF405S) [clone: HSPD1/780]

Supplier: Biotium
Description: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (HSPs), more appropriately called as stress response proteins (SRPs). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Image-CA10820-448

HC103 Moisture Analyzer

Catalog Number: (CA10820-448)
Supplier: Mettler Toledo
Description: The HC103 halogen moisture analyzer combines fast halogen heating with proven weighing technology to create a compact and durable instrument ideal for laboratory and production environments. Halogen heating element.
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