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Product Image-10068-526

Anti-ATF2 Rabbit Polyclonal Antibody

Catalog Number: (10068-526)
Supplier: Prosci
Description: Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
Product Image-10068-718

Anti-SRC Rabbit Polyclonal Antibody

Catalog Number: (10068-718)
Supplier: Prosci
Description: proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme; phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme.
Product Image-10068-858

Anti-FOXO4 Rabbit Polyclonal Antibody

Catalog Number: (10068-858)
Supplier: Prosci
Description: Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.
Product Image-10068-942

Anti-EGFR Rabbit Polyclonal Antibody

Catalog Number: (10068-942)
Supplier: Prosci
Description: Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.
Product Image-10071-864

Anti-NFKBIA Rabbit Polyclonal Antibody

Catalog Number: (10071-864)
Supplier: Prosci
Description: Inhibits the activity of dimeric NF-κ-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.
Product Image-10068-762

Anti-IRS1 Rabbit Polyclonal Antibody

Catalog Number: (10068-762)
Supplier: Prosci
Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit
Image Unavailable-CAPI26614

PageRuler™ Unstained Protein Ladder

Catalog Number: (CAPI26614)
Supplier: Thermo Scientific
Description: Thermo Scientific PageRuler Unstained Protein Ladder is a mixture of 14 recombinant, highly purified, unstained proteins (10kDa to 200kDa) for use as size standards in protein electrophoresis (SDS-PAGE) and Western blotting.

SDS


Image Unavailable-77208-604

Mouse Agpat1 ELISA Kit

Catalog Number: (77208-604)
Supplier: ANTIBODIES.COM LLC
Description: Mouse Agpat1 ELISA kit is a 90 minute sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of mouse Agpat1 in serum, plasma, and other biological fluids.
Image Unavailable-CAPI26635

PageRuler™ Prestained NIR Protein Ladder

Catalog Number: (CAPI26635)
Supplier: Thermo Scientific
Description: Thermo Scientific PageRuler Prestained NIR Protein Ladder is a mixture of 10 proteins (11 to 250KDa) that are blue-stained and fluor-labeled for near-IR fluorescent visualization and protein sizing following electrophoresis.

SDS Certificates


Product Image-10070-400

Anti-MAPK3 Rabbit Polyclonal Antibody

Catalog Number: (10070-400)
Supplier: Prosci
Description: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1
Product Image-10071-926

Anti-Cry1 Rabbit Polyclonal Antibody

Catalog Number: (10071-926)
Supplier: Prosci
Description: Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL
Product Image-10071-856

Anti-SRC Rabbit Polyclonal Antibody

Catalog Number: (10071-856)
Supplier: Prosci
Description: proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme; phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme.
Image Unavailable-10407-046

Anti-AGPAT2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10407-046)
Supplier: Bioss
Description: Agpat2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. It is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Product Image-10070-054

Anti-SUFU Rabbit Polyclonal Antibody

Catalog Number: (10070-054)
Supplier: Prosci
Description: SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700)
Product Image-10068-932

Anti-EGFR Rabbit Polyclonal Antibody

Catalog Number: (10068-932)
Supplier: Prosci
Description: Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.
Product Image-10070-892

Anti-MDM2 Rabbit Polyclonal Antibody

Catalog Number: (10070-892)
Supplier: Prosci
Description: MDM2, a ubiquitin ligase for p53, plays a central role in regulation of the stability of p53. Akt-mediated phosphorylation of MDM2 at Ser166 and Ser186 increases its interaction with p300, allowing MDM2-mediated ubiquitination and degradation of p53. Phosphorylation of MDM2 also blocks its binding to p19ARF, increasing the degradation of p53.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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